Click here to switch to the map view.

The map label for this gene is deoC [H]

Identifier: 22127614

GI number: 22127614

Start: 4162486

End: 4163298

Strand: Reverse

Name: deoC [H]

Synonym: y3743

Alternate gene names: 22127614

Gene position: 4163298-4162486 (Counterclockwise)

Preceding gene: 22127615

Following gene: 22127613

Centisome position: 90.49

GC content: 50.06

Gene sequence:

>813_bases
GTGTTGGAGAGTTTTATGACCGATTTAACCGCCTGCGCGCATTTGAACGATTATGCTAAACGCGCACTAAGTTTGATGGA
TTTAACCACCCTGAATGACGACGATACTGATGAAAAAGTGATCGCGCTCTGTCATCAGGCTAAAAGCCCGGCCGGTAATA
CCGCGGCAATTTGTATTTATCCTCGCTTTATCCCGGTTGCCCGTAAGGCGTTACGTGAGCAGGGCACTCCTGAGATCCGT
ATCGCAACGGTGACCAACTTCCCTCATGGCAATGATGATGTTGCGATTGCGTTGGCTGAAACCCGTGCTGCCATTGCTTA
TGGTGCCGATGAAGTGGATGTGGTTTTCCCTTATCGCGCGTTAATGGCCGGTAACGATAAAATTGGCTTCGAACTCGTGA
AAACGTGTAAAGAAGCCTGCGCTGCGGCGAATGTATTACTGAAAGTCATCATTGAAACTGGCGAACTTAAGCAAGCGCAT
TTAATTCGTCAGGCCTCTGAAATTGCAATCAAAGCGGGTGCCGATTTTATTAAAACTTCTACCGGTAAAGTGCCGGTGAA
TGCCACGTTGGAAAGTGCAGACATTATGATCCGCACTATCCGTGAGTTAGGCGTAGGCGAAACGGTGGGCTTCAAACCGG
CTGGTGGTGTCCGTACCGCAGAAGATGCCGCGCAATTTTTGCAATTGGCTGATCAACTGATGGGGGAAGGCTGGGCTGAT
GCACGCCATTTCCGCTTTGGCGCTTCCAGTCTACTCGCCAGTTTGCTGACCACATTGGGTCACCAGAGTAACGCCAACAG
CAGCGGCTACTAA

Upstream 100 bases:

>100_bases
CTCGCCAACGTATTGAGCTTAACCACCGAGAGATACCGCCAAGGATCTTTTCTGCTCATAACTACATGCTCAGTTTTGGC
AAACTGCCGGAGCTGAAACA

Downstream 100 bases:

>100_bases
CGTTATTATCATCATTACACTGAATTGATGCACAGTAGGCTGAAGGCCTGCTGTGTCGCTATTTCCGAAAGCGCCTGTGG
GCGGCTTTCATCCCATATTC

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase 2; DERA 2; Deoxyriboaldolase 2 [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLESFMTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIYPRFIPVARKALREQGTPEIR
IATVTNFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRALMAGNDKIGFELVKTCKEACAAANVLLKVIIETGELKQAH
LIRQASEIAIKAGADFIKTSTGKVPVNATLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWAD
ARHFRFGASSLLASLLTTLGHQSNANSSGY

Sequences:

>Translated_270_residues
MLESFMTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIYPRFIPVARKALREQGTPEIR
IATVTNFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRALMAGNDKIGFELVKTCKEACAAANVLLKVIIETGELKQAH
LIRQASEIAIKAGADFIKTSTGKVPVNATLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWAD
ARHFRFGASSLLASLLTTLGHQSNANSSGY
>Mature_270_residues
MLESFMTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIYPRFIPVARKALREQGTPEIR
IATVTNFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRALMAGNDKIGFELVKTCKEACAAANVLLKVIIETGELKQAH
LIRQASEIAIKAGADFIKTSTGKVPVNATLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWAD
ARHFRFGASSLLASLLTTLGHQSNANSSGY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116063554, Length=267, Percent_Identity=37.4531835205993, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1790841, Length=265, Percent_Identity=78.4905660377359, Blast_Score=384, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17533015, Length=251, Percent_Identity=37.4501992031873, Blast_Score=157, Evalue=6e-39,
Organism=Drosophila melanogaster, GI19922098, Length=255, Percent_Identity=37.6470588235294, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.4 [H]

Molecular weight: Translated: 28882; Mature: 28882

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESFMTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEE
PRFIPVARKALREQGTPEIRIATVTNFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRA
CCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEHHHHHHHCCCCCEEEEECHHH
LMAGNDKIGFELVKTCKEACAAANVLLKVIIETGELKQAHLIRQASEIAIKAGADFIKTS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCC
TGKVPVNATLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWAD
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ARHFRFGASSLLASLLTTLGHQSNANSSGY
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLESFMTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEE
PRFIPVARKALREQGTPEIRIATVTNFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRA
CCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEHHHHHHHCCCCCEEEEECHHH
LMAGNDKIGFELVKTCKEACAAANVLLKVIIETGELKQAHLIRQASEIAIKAGADFIKTS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCC
TGKVPVNATLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWAD
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ARHFRFGASSLLASLLTTLGHQSNANSSGY
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]