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The map label for this gene is yeiJ [C]

Identifier: 22127615

GI number: 22127615

Start: 4163891

End: 4165198

Strand: Reverse

Name: yeiJ [C]

Synonym: y3744

Alternate gene names: 22127615

Gene position: 4165198-4163891 (Counterclockwise)

Preceding gene: 22127616

Following gene: 22127614

Centisome position: 90.53

GC content: 50.46

Gene sequence:

>1308_bases
GTGACTAATAGCCTTATTATTAATAGGAATATCGACATGCTCATGAGTTTGGTCGGGATGGCAGTACTGATATTAATCGC
TGTACTGCTTTCAAGTAATGCCAGGGCGATTAATCTTCGCACTGTCATCGGTGCATTTATTATCCAAGTGGTGATTGGTG
CGCTGGTGCTATATGTACCGGTTGGCCGCCGTATTCTGGGGGGGATGTCGGAAGGAGTCGCTAACGTTATTGCTTATGGT
AATGAAGGGATCTCATTTATTTTTGGCGGATTGGTTTCCGACAAAATGTATGAAGTCTTTGGCGGTGGGGGTTTTGTATT
CGCCTTACGTGTATTACCGGTAATTGTATTCTTCTCGTCATTGATTGCGGTGTTGTATTACCTCGGCGTCATGCAAATCG
TGATTAAAGTATTGGGCGGTGGTTTACAAAAACTGCTGGGCACCTCGCGGACGGAGTCTCTTTCTGCCACAGCCAATATT
TTCGTTGGGCAGACAGAAGCGCCGTTAGTTGTTCGCCCCTATATTGCAACCATGACTCAGTCAGAACTGTTTGCGGTCAT
GTGTGGTGGCCTGGCCTCGGTTGCAGGCTCGGTATTGGCCGGGTATGCGCAAATGGGCGTACCGTTGGAATATTTGATTG
CCGCCTCCTTTATGGCAGCACCGGGCGGGTTACTGTTCGCCAAATTAATGGTGCCTGAAACCGAGCAAACCCACGATAAA
GTTGATGCTATCGCACTGATCGCGGAAGAGGACCGCCCGGCTAACGTTATTGATGCCGCAGCTTCTGGGGCAGCCTCTGG
TATGCAACTGGCGCTGAATGTCGGGGCGATGCTATTGGCTTTTATCGCATTGATTGCATTGCTTAATGGCATTCTGGGGG
GGATTGGCGGCTGGTTCGATTATCCGCAACTCTCGCTGGAATTGATTCTGGGCTGGGTGTTCTCGCCAATCGCTTATCTG
ATCGGCGTGCCATGGAGCGAAGCAATGGTGGCGGGCTCCTTTATCGGCCAAAAGATTATCGTTAACGAGTTCGTGGCCTT
TATGAATTTTGGTCAGTATTTGCAGGCGGACGAACTGGTGAAAGCGGCTGGTTTACAGGTGCTCTCTGAACACACCAAAG
CGATCATCTCTTTTGCCCTGTGTGGGTTCGCTAACTTGTCTTCGGTAGCTATTCTACTGGGTGGGCTGGGTAGCATGGCA
CCAAATCGTCGTCATGATATTGCGCGCTTTGGCCTGAAAGCCGTGGCCGCAGGGACGTTGTCGAATTTGATGAGTGCGAC
GATCGCCGGCTTCTTCCTGGCACTGTGA

Upstream 100 bases:

>100_bases
CACATTTACATCTTTGTAGTTGCTTCCATTTGTGTTTATTTGTGACGGAGATTACTTGATAGCGAGGTGATGACGTTATA
ATTGCCGACATCATTTCAAT

Downstream 100 bases:

>100_bases
TGTATAAGGTGCCGTTTTTGTCAAACGGCACATGCTATCAGGCGTATTCTCACCAATACGCTATTCTTGATACGAATAGC
GTAATCGGGGCCAATAGACC

Product: transport system permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MTNSLIINRNIDMLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVGRRILGGMSEGVANVIAYG
NEGISFIFGGLVSDKMYEVFGGGGFVFALRVLPVIVFFSSLIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANI
FVGQTEAPLVVRPYIATMTQSELFAVMCGGLASVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDK
VDAIALIAEEDRPANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGWVFSPIAYL
IGVPWSEAMVAGSFIGQKIIVNEFVAFMNFGQYLQADELVKAAGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMA
PNRRHDIARFGLKAVAAGTLSNLMSATIAGFFLAL

Sequences:

>Translated_435_residues
MTNSLIINRNIDMLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVGRRILGGMSEGVANVIAYG
NEGISFIFGGLVSDKMYEVFGGGGFVFALRVLPVIVFFSSLIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANI
FVGQTEAPLVVRPYIATMTQSELFAVMCGGLASVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDK
VDAIALIAEEDRPANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGWVFSPIAYL
IGVPWSEAMVAGSFIGQKIIVNEFVAFMNFGQYLQADELVKAAGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMA
PNRRHDIARFGLKAVAAGTLSNLMSATIAGFFLAL
>Mature_434_residues
TNSLIINRNIDMLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVGRRILGGMSEGVANVIAYGN
EGISFIFGGLVSDKMYEVFGGGGFVFALRVLPVIVFFSSLIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANIF
VGQTEAPLVVRPYIATMTQSELFAVMCGGLASVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDKV
DAIALIAEEDRPANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGWVFSPIAYLI
GVPWSEAMVAGSFIGQKIIVNEFVAFMNFGQYLQADELVKAAGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMAP
NRRHDIARFGLKAVAAGTLSNLMSATIAGFFLAL

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI11545853, Length=426, Percent_Identity=38.4976525821596, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI42542381, Length=433, Percent_Identity=38.568129330254, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI227116277, Length=426, Percent_Identity=37.3239436619718, Blast_Score=278, Evalue=1e-74,
Organism=Escherichia coli, GI1788485, Length=425, Percent_Identity=50.1176470588235, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1788488, Length=425, Percent_Identity=49.1764705882353, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1788737, Length=424, Percent_Identity=32.0754716981132, Blast_Score=189, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17560276, Length=402, Percent_Identity=31.8407960199005, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI71991794, Length=424, Percent_Identity=29.7169811320755, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI25146537, Length=221, Percent_Identity=29.8642533936652, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45552517, Length=422, Percent_Identity=38.8625592417062, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI19921868, Length=422, Percent_Identity=38.8625592417062, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI45552519, Length=422, Percent_Identity=38.8625592417062, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI281360430, Length=414, Percent_Identity=37.43961352657, Blast_Score=250, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 45511; Mature: 45379

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSLIINRNIDMLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVP
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
VGRRILGGMSEGVANVIAYGNEGISFIFGGLVSDKMYEVFGGGGFVFALRVLPVIVFFSS
HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANIFVGQTEAPLVVRPYIATMTQ
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHEEEEECCCCCEEEEHHHHHHHH
SELFAVMCGGLASVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHH
VDAIALIAEEDRPANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFD
HHHHEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YPQLSLELILGWVFSPIAYLIGVPWSEAMVAGSFIGQKIIVNEFVAFMNFGQYLQADELV
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAAGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMAPNRRHDIARFGLKAVAAGTL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
SNLMSATIAGFFLAL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNSLIINRNIDMLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVP
CCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
VGRRILGGMSEGVANVIAYGNEGISFIFGGLVSDKMYEVFGGGGFVFALRVLPVIVFFSS
HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANIFVGQTEAPLVVRPYIATMTQ
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHEEEEECCCCCEEEEHHHHHHHH
SELFAVMCGGLASVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHH
VDAIALIAEEDRPANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFD
HHHHEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YPQLSLELILGWVFSPIAYLIGVPWSEAMVAGSFIGQKIIVNEFVAFMNFGQYLQADELV
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAAGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMAPNRRHDIARFGLKAVAAGTL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
SNLMSATIAGFFLAL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]