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The map label for this gene is surA [H]

Identifier: 22127555

GI number: 22127555

Start: 4092544

End: 4093848

Strand: Direct

Name: surA [H]

Synonym: y3681

Alternate gene names: 22127555

Gene position: 4092544-4093848 (Clockwise)

Preceding gene: 161484744

Following gene: 22127556

Centisome position: 88.95

GC content: 48.58

Gene sequence:

>1305_bases
ATGAAGAACTGGAGAACGCTTATTCTCGGATTGGTCATTTGTGCCAATACCGCGTTCGCAGCACCACAAGAAGTTGATAA
AGTTGCCGCGGTGGTTGATAACGGTGTTGTGTTACAAAGTGATATCGACGGCCTGCTACAATCGGTAAAAATGAACGCAC
AACAATCTGGGCAGCAGGTTCCGGATGATTCGACATTACGCCACCAAATTCTTGAACGCCTCATCATGGATAATATCCAA
CTGCAGATGGCCAAGAAAATGGGTATTACCATCACTGACCAGGCGCTGGATAAAGCCATTGCAGATATTGCGGCCCAAAA
CCGCATGACGCTCGCTCAGATGCGTAGCCGTTTAGCCGCTGATGGCCTTAGCTACGATACTTACCGTGAGCAAATCCGCA
AAGAAATGCTGACATCAGAAGTCCGTAACAATGAAGTCCGTCGCCGGATAACCATTTTGCCGCAAGAAGTTGAATCTCTG
GCTAAGCAGATGGGTAATCAAGTCAGTGGTGATACCGAACTGAATCTCAGCCACATCCTGATTCCATTGCCAGAAAATCC
AACTCAGCAGCAAGTTGATCAAGCTGAAGATCTGGCGAACAAATTGGTTGCTGACATTAAAGGCGGTGCGGATTTTGGTA
AATTAGCTATCGCGAATTCAGCTGACTCTCAAGCTCTGAAAGGCGGCCAAATGGGTTGGGGGAAACTGCAGGAGTTACCT
TCACTGTTTGCCGAGAGACTGCAATCGGCGCATAAAGGCGAGATTGTCGGTCCTATCCGTTCAGGTGTCGGGTTCCATAT
TTTGAAAGTGAATGACATGCGTGGGGCGGATCAAACCATTTCCGTTACTGAAGTGAATGCACGACACATCCTGTTGAAAC
CTTCACCAATGATGACCGACGAGCAAGCTCGCGCCAAGTTGGAAGCCGCCGCCGCAGAGATTAAAAGCGGAAAAACGAGC
TTCGCGACTATCGCCAAAGAAATTTCGCAGGATCCCGGCTCAGCGATGCAAGGCGGGGAACTGGGTTGGGCATCACCCGA
TATTTACGATCCAGCCTTCCGTGATGCATTGATGAAACTGAAGAAAGGTGAAATCAGTGCCCCTGTTCACTCTTCCTTCG
GTTGGCACCTCATTCAGCTTGTCGATACCCGTCAGGTAGATAAAACGGATGCCGCACAAAAAGAGCGGGCGTACCGTATG
CTCTTCAACCGTAAATTTGCTGAAGAAGCACAAACCTGGATGCAAGAGCAGCGTGCTGCTGCTTATGTAAAAATTCTTGA
TGGTAGTAATGCACAACCACAATAA

Upstream 100 bases:

>100_bases
TCGGGCATTCTGCCTTATCAAAGTGCATTCTGATACTGTTTAACACACTGAATACAGTGAATCTTAACCCGCGATAGCGG
ATTACATAAATGGAAAAGGT

Downstream 100 bases:

>100_bases
TCGTCTAGTGATCACCCCCGGCGAGCCAGCCGGGGTCGGGCCGGATTTAGCCATCACTCTGGCTCAACAGGATTGGCCTG
TTGAGCTGGTAGTCTGCGCG

Product: peptidyl-prolyl cis-trans isomerase SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKNWRTLILGLVICANTAFAAPQEVDKVAAVVDNGVVLQSDIDGLLQSVKMNAQQSGQQVPDDSTLRHQILERLIMDNIQ
LQMAKKMGITITDQALDKAIADIAAQNRMTLAQMRSRLAADGLSYDTYREQIRKEMLTSEVRNNEVRRRITILPQEVESL
AKQMGNQVSGDTELNLSHILIPLPENPTQQQVDQAEDLANKLVADIKGGADFGKLAIANSADSQALKGGQMGWGKLQELP
SLFAERLQSAHKGEIVGPIRSGVGFHILKVNDMRGADQTISVTEVNARHILLKPSPMMTDEQARAKLEAAAAEIKSGKTS
FATIAKEISQDPGSAMQGGELGWASPDIYDPAFRDALMKLKKGEISAPVHSSFGWHLIQLVDTRQVDKTDAAQKERAYRM
LFNRKFAEEAQTWMQEQRAAAYVKILDGSNAQPQ

Sequences:

>Translated_434_residues
MKNWRTLILGLVICANTAFAAPQEVDKVAAVVDNGVVLQSDIDGLLQSVKMNAQQSGQQVPDDSTLRHQILERLIMDNIQ
LQMAKKMGITITDQALDKAIADIAAQNRMTLAQMRSRLAADGLSYDTYREQIRKEMLTSEVRNNEVRRRITILPQEVESL
AKQMGNQVSGDTELNLSHILIPLPENPTQQQVDQAEDLANKLVADIKGGADFGKLAIANSADSQALKGGQMGWGKLQELP
SLFAERLQSAHKGEIVGPIRSGVGFHILKVNDMRGADQTISVTEVNARHILLKPSPMMTDEQARAKLEAAAAEIKSGKTS
FATIAKEISQDPGSAMQGGELGWASPDIYDPAFRDALMKLKKGEISAPVHSSFGWHLIQLVDTRQVDKTDAAQKERAYRM
LFNRKFAEEAQTWMQEQRAAAYVKILDGSNAQPQ
>Mature_434_residues
MKNWRTLILGLVICANTAFAAPQEVDKVAAVVDNGVVLQSDIDGLLQSVKMNAQQSGQQVPDDSTLRHQILERLIMDNIQ
LQMAKKMGITITDQALDKAIADIAAQNRMTLAQMRSRLAADGLSYDTYREQIRKEMLTSEVRNNEVRRRITILPQEVESL
AKQMGNQVSGDTELNLSHILIPLPENPTQQQVDQAEDLANKLVADIKGGADFGKLAIANSADSQALKGGQMGWGKLQELP
SLFAERLQSAHKGEIVGPIRSGVGFHILKVNDMRGADQTISVTEVNARHILLKPSPMMTDEQARAKLEAAAAEIKSGKTS
FATIAKEISQDPGSAMQGGELGWASPDIYDPAFRDALMKLKKGEISAPVHSSFGWHLIQLVDTRQVDKTDAAQKERAYRM
LFNRKFAEEAQTWMQEQRAAAYVKILDGSNAQPQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=426, Percent_Identity=75.3521126760563, Blast_Score=658, Evalue=0.0,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 47734; Mature: 47734

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWRTLILGLVICANTAFAAPQEVDKVAAVVDNGVVLQSDIDGLLQSVKMNAQQSGQQV
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCC
PDDSTLRHQILERLIMDNIQLQMAKKMGITITDQALDKAIADIAAQNRMTLAQMRSRLAA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DGLSYDTYREQIRKEMLTSEVRNNEVRRRITILPQEVESLAKQMGNQVSGDTELNLSHIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEE
IPLPENPTQQQVDQAEDLANKLVADIKGGADFGKLAIANSADSQALKGGQMGWGKLQELP
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCHHHHHHHH
SLFAERLQSAHKGEIVGPIRSGVGFHILKVNDMRGADQTISVTEVNARHILLKPSPMMTD
HHHHHHHHHHCCCCEECHHHCCCCEEEEEEECCCCCCCEEEEEEECCCEEEECCCCCCCC
EQARAKLEAAAAEIKSGKTSFATIAKEISQDPGSAMQGGELGWASPDIYDPAFRDALMKL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
KKGEISAPVHSSFGWHLIQLVDTRQVDKTDAAQKERAYRMLFNRKFAEEAQTWMQEQRAA
HCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYVKILDGSNAQPQ
HEEEEECCCCCCCC
>Mature Secondary Structure
MKNWRTLILGLVICANTAFAAPQEVDKVAAVVDNGVVLQSDIDGLLQSVKMNAQQSGQQV
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCC
PDDSTLRHQILERLIMDNIQLQMAKKMGITITDQALDKAIADIAAQNRMTLAQMRSRLAA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DGLSYDTYREQIRKEMLTSEVRNNEVRRRITILPQEVESLAKQMGNQVSGDTELNLSHIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEE
IPLPENPTQQQVDQAEDLANKLVADIKGGADFGKLAIANSADSQALKGGQMGWGKLQELP
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCHHHHHHHH
SLFAERLQSAHKGEIVGPIRSGVGFHILKVNDMRGADQTISVTEVNARHILLKPSPMMTD
HHHHHHHHHHCCCCEECHHHCCCCEEEEEEECCCCCCCEEEEEEECCCEEEECCCCCCCC
EQARAKLEAAAAEIKSGKTSFATIAKEISQDPGSAMQGGELGWASPDIYDPAFRDALMKL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
KKGEISAPVHSSFGWHLIQLVDTRQVDKTDAAQKERAYRMLFNRKFAEEAQTWMQEQRAA
HCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYVKILDGSNAQPQ
HEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA