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The map label for this gene is yhdT [H]

Identifier: 21242292

GI number: 21242292

Start: 1782258

End: 1783580

Strand: Reverse

Name: yhdT [H]

Synonym: XAC1541

Alternate gene names: 21242292

Gene position: 1783580-1782258 (Counterclockwise)

Preceding gene: 21242294

Following gene: 21242290

Centisome position: 34.46

GC content: 64.7

Gene sequence:

>1323_bases
ATGTTGGGTAACGTCCTGCTGCTGTTGGTGGCATTGCTGCTGGTGCTGTTGAATGGATTTTTTGTCGCCGCCGAGTTCGC
GCTGGTCAAGCTGCGGCACACGCAAGCGGTGGGCCTGGCGCAAACCAACGGCTGGCGCGGGCGCTTGTTGCTCGGTGTAC
ACGCGCATCTGGATGCGTATCTGTCGGCCTGCCAGCTCGGTATCACGCTGGCTTCGCTCGGATTGGGCTGGGTCGGCGAG
CCGGCTTTCGCACATCTGCTGCAACCGCTGTTCGATACGCTGGGCCTGTCGCCGGAAGCGGCACAATTCACTGCGCTGGC
AATCGCCTTCAGCTTGATTTCGTTCCTGCATATCGTGCTGGGCGAACTGGCGCCCAAGACCATGGCGATCCGCCGCCCGG
AACGCATGTCGTTGTGGACCGCTGCGCCGCTGTACGTTTTCTACTGGCTGATGTACCCGGCCATCTGGGTGCTCAATACC
AGCGCCAACCGCTTTCTGCGCCTGCTCGGCTGGGGCGAGGTGGAACATCACTCGCATCGTTACTCACGCGAGGAACTGAT
GCTGATCGTCGGCCGCCAGGACCCGAACGCCGCTGCGCCCGACCAGGGGCTGGCCTTGATGAGCCACGCGTTGGAATTGC
CGGATCTGGTCGCCGGCGATTTGATGCGCCCGCGCGAGCACATGCGCAGCCTGCGCGAAGGCATGACCCTGGAGACGGTG
CTGGCCGAATTCAGTGAGTCGCGCTACAGCCGCTACCCCTGGTTCGATGCCGATGGCGAACAGGTACTCGGCATCCTGCA
CACCAAGGATTTGCTGGTGGCGATGGCACGCGGCCAGAACCTGGACGATCTGCGCCCGCTGCTGCGCCCTCCCACCGTGC
TGACCCTGGAAACGCCGATTCCCAACGCGCTGGAGCAATTCCGCACCGGCACCACCCATCTGGCGCTGTGCGTGGAAGAA
GAAGGCCGCATCCTGGGCTTTTTCACCCTGGAAGACCTGCTGGAAGTGGTGGTTGGCGACATCGAGGACGAGCACCGACA
CGTGGTGCGCGATGCCCCGATCCGTGGCCAGGACGGCTCGCTGCTGGTCGCCGGCAGCACCTCGATCTTCCGCCTGGAAC
GCCTGCTCGGTCAGGACCTGAGCGCGCCGGACCACGTCAATTCGGTCGGCGGGCTGATCCTGTGTCAGCTGCAGCGCCTG
CCCGAGGAAGGCGAAACGCTGGAGCTGGATGGTCACCTGCTGACCGTGCGGCGCATGGCAGGCCATCGCATCCAGGCAGT
CACGGTGCGCCCGGTGGGCGAAGCCGTCGACGCGGCCAGCTGA

Upstream 100 bases:

>100_bases
AGAAACGCACGTTCCGCATCGGTTGCCGCGACACTGCTCATCGCTACCGCACATGCGGTGGCACGCGGATGGACCGCTCC
TGCAGCGCATGGAGGCGGCC

Downstream 100 bases:

>100_bases
TGCCGTCGATTCAGTCGGCGGACGCGCGAGCCGATTGGCCGATGCGAAACCAATAACGGTAATCGCGCGACTGCCCGCCG
AACCGCACCCCGCGGATGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MLGNVLLLLVALLLVLLNGFFVAAEFALVKLRHTQAVGLAQTNGWRGRLLLGVHAHLDAYLSACQLGITLASLGLGWVGE
PAFAHLLQPLFDTLGLSPEAAQFTALAIAFSLISFLHIVLGELAPKTMAIRRPERMSLWTAAPLYVFYWLMYPAIWVLNT
SANRFLRLLGWGEVEHHSHRYSREELMLIVGRQDPNAAAPDQGLALMSHALELPDLVAGDLMRPREHMRSLREGMTLETV
LAEFSESRYSRYPWFDADGEQVLGILHTKDLLVAMARGQNLDDLRPLLRPPTVLTLETPIPNALEQFRTGTTHLALCVEE
EGRILGFFTLEDLLEVVVGDIEDEHRHVVRDAPIRGQDGSLLVAGSTSIFRLERLLGQDLSAPDHVNSVGGLILCQLQRL
PEEGETLELDGHLLTVRRMAGHRIQAVTVRPVGEAVDAAS

Sequences:

>Translated_440_residues
MLGNVLLLLVALLLVLLNGFFVAAEFALVKLRHTQAVGLAQTNGWRGRLLLGVHAHLDAYLSACQLGITLASLGLGWVGE
PAFAHLLQPLFDTLGLSPEAAQFTALAIAFSLISFLHIVLGELAPKTMAIRRPERMSLWTAAPLYVFYWLMYPAIWVLNT
SANRFLRLLGWGEVEHHSHRYSREELMLIVGRQDPNAAAPDQGLALMSHALELPDLVAGDLMRPREHMRSLREGMTLETV
LAEFSESRYSRYPWFDADGEQVLGILHTKDLLVAMARGQNLDDLRPLLRPPTVLTLETPIPNALEQFRTGTTHLALCVEE
EGRILGFFTLEDLLEVVVGDIEDEHRHVVRDAPIRGQDGSLLVAGSTSIFRLERLLGQDLSAPDHVNSVGGLILCQLQRL
PEEGETLELDGHLLTVRRMAGHRIQAVTVRPVGEAVDAAS
>Mature_440_residues
MLGNVLLLLVALLLVLLNGFFVAAEFALVKLRHTQAVGLAQTNGWRGRLLLGVHAHLDAYLSACQLGITLASLGLGWVGE
PAFAHLLQPLFDTLGLSPEAAQFTALAIAFSLISFLHIVLGELAPKTMAIRRPERMSLWTAAPLYVFYWLMYPAIWVLNT
SANRFLRLLGWGEVEHHSHRYSREELMLIVGRQDPNAAAPDQGLALMSHALELPDLVAGDLMRPREHMRSLREGMTLETV
LAEFSESRYSRYPWFDADGEQVLGILHTKDLLVAMARGQNLDDLRPLLRPPTVLTLETPIPNALEQFRTGTTHLALCVEE
EGRILGFFTLEDLLEVVVGDIEDEHRHVVRDAPIRGQDGSLLVAGSTSIFRLERLLGQDLSAPDHVNSVGGLILCQLQRL
PEEGETLELDGHLLTVRRMAGHRIQAVTVRPVGEAVDAAS

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=412, Percent_Identity=32.5242718446602, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI94681046, Length=253, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40068053, Length=256, Percent_Identity=25.78125, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI40068055, Length=256, Percent_Identity=25.78125, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1790664, Length=442, Percent_Identity=23.0769230769231, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI145693175, Length=337, Percent_Identity=24.6290801186944, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082033, Length=215, Percent_Identity=31.6279069767442, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=28.3464566929134, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48633; Mature: 48633

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGNVLLLLVALLLVLLNGFFVAAEFALVKLRHTQAVGLAQTNGWRGRLLLGVHAHLDAY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEEHHHHHHH
LSACQLGITLASLGLGWVGEPAFAHLLQPLFDTLGLSPEAAQFTALAIAFSLISFLHIVL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GELAPKTMAIRRPERMSLWTAAPLYVFYWLMYPAIWVLNTSANRFLRLLGWGEVEHHSHR
HHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCHHHHHHH
YSREELMLIVGRQDPNAAAPDQGLALMSHALELPDLVAGDLMRPREHMRSLREGMTLETV
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCHHHHH
LAEFSESRYSRYPWFDADGEQVLGILHTKDLLVAMARGQNLDDLRPLLRPPTVLTLETPI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCC
PNALEQFRTGTTHLALCVEEEGRILGFFTLEDLLEVVVGDIEDEHRHVVRDAPIRGQDGS
CHHHHHHCCCCCEEEEEEECCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCC
LLVAGSTSIFRLERLLGQDLSAPDHVNSVGGLILCQLQRLPEEGETLELDGHLLTVRRMA
EEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEHHC
GHRIQAVTVRPVGEAVDAAS
CCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MLGNVLLLLVALLLVLLNGFFVAAEFALVKLRHTQAVGLAQTNGWRGRLLLGVHAHLDAY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEEHHHHHHH
LSACQLGITLASLGLGWVGEPAFAHLLQPLFDTLGLSPEAAQFTALAIAFSLISFLHIVL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GELAPKTMAIRRPERMSLWTAAPLYVFYWLMYPAIWVLNTSANRFLRLLGWGEVEHHSHR
HHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCHHHHHHH
YSREELMLIVGRQDPNAAAPDQGLALMSHALELPDLVAGDLMRPREHMRSLREGMTLETV
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCHHHHH
LAEFSESRYSRYPWFDADGEQVLGILHTKDLLVAMARGQNLDDLRPLLRPPTVLTLETPI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCC
PNALEQFRTGTTHLALCVEEEGRILGFFTLEDLLEVVVGDIEDEHRHVVRDAPIRGQDGS
CHHHHHHCCCCCEEEEEEECCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCC
LLVAGSTSIFRLERLLGQDLSAPDHVNSVGGLILCQLQRLPEEGETLELDGHLLTVRRMA
EEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEHHC
GHRIQAVTVRPVGEAVDAAS
CCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]