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The map label for this gene is 21241444

Identifier: 21241444

GI number: 21241444

Start: 798252

End: 799307

Strand: Direct

Name: 21241444

Synonym: XAC0673

Alternate gene names: NA

Gene position: 798252-799307 (Clockwise)

Preceding gene: 21241442

Following gene: 21241445

Centisome position: 15.42

GC content: 64.49

Gene sequence:

>1056_bases
ATGGCAACACCGTACCACTATCTCGTGTTTATCGGGCGTTTCGAGCCCTTTCATAACGGCCACGCCGCCGTCGCCCGCCA
CGCGCTGGGCAAGGCGAAAAAGCTCATCGTGCTGATCGGCTCGGCCGACACGCCCCGCACCATTCGCAATCCTTGGACCG
TCGCCGAACGTGCGGTGATGATCGAATCCGCGTTGCCGGGCGAAACCGCGCGGTTGCTCGTGCGCCCGCTACGCGACCAT
CTGTACAACGAAAGCCTGTGGATCGCCGAAGTGCAGCGGCAGGTTGCCGAAGCGGTGCACGCCGATGGCGGCACGCTGGA
TGCGAACATCGGCCTGATCGGCATGGACAAGGATGCCAGCAGCTACTACCTGCGTGAGTTTCCGCAGTGGCCGCTGGAGG
ACGTGCAACATACCGCAACGCTGTCGGCCACCGAATTGCGCCGCTATCTGTTCGAAGCCGGCGACATCGGTTTCCACGGC
GGCTTGTTGATGCTGCGCGGCAATGTGCCGGCGCCCGTCTACGACATGCTGGAGGCCTTCCGGCGCAACTCGCCCAGCTA
CGCGCAGCTGGTGGCCGAATACCGCTTCATCGAGCAATACCGCGCCGCGTGGAAAGACGCGCCATATCCGCCGACATTCG
TGACCACCGATGCGGTGGTGGTGCATTCGGGCCATGTGCTGCTGGTGCGGCGTCGCGCCGAACCGGGCAAGGGATTGTGG
GCGTTGCCTGGCGGTTTCGTCGGCCAGGAGGAAGGGCTGCTGGATTGCTGCCTGCGCGAGTTGCGCGAGGAAACCCGGCT
CAAGTTGCCGGTGCCGGTGCTCAAGGGCTCGTTGCGTGGCAGGCAGGTCTTCGATCATCCCGAGCGCAGTCAGCGCGGAC
GCACCATTACCCATGCGTTCCATTTCGAGTTTCCGGCCGGGGAGTTGCCTGCGGTGCGCGGCGGCGACGATGCCGACAAG
GCGCGCTGGATTCCGCTCGCCGAAGTGATGGCGATGGGCCCGCGCCTGTACGAAGACCACCTGCACATTCTTGAATTCTT
CCTGGGCCGTGGCTGA

Upstream 100 bases:

>100_bases
CACAGGCAAGCGGCCGCTTGACGCCGTCGTGCATCGGCGTAGCATTTCACCAAGCCGGCGGACAGACCGCCAGCTCACCA
CTCAACCGTGAGGGATTCTC

Downstream 100 bases:

>100_bases
CGCGCGCAAACGACGACGTGCTGCCGCGATACCACCAGGGGCGCACATGCCGTGACCGCTTGAACCGTGACCTCCCGCCG
GCGGACAGACCGCCGGTTCA

Product: bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: Nicotinamide-nucleotide adenylyltransferase; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NMN adenylyltransferase; ADP compounds hydrolase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MATPYHYLVFIGRFEPFHNGHAAVARHALGKAKKLIVLIGSADTPRTIRNPWTVAERAVMIESALPGETARLLVRPLRDH
LYNESLWIAEVQRQVAEAVHADGGTLDANIGLIGMDKDASSYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHG
GLLMLRGNVPAPVYDMLEAFRRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLW
ALPGGFVGQEEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAFHFEFPAGELPAVRGGDDADK
ARWIPLAEVMAMGPRLYEDHLHILEFFLGRG

Sequences:

>Translated_351_residues
MATPYHYLVFIGRFEPFHNGHAAVARHALGKAKKLIVLIGSADTPRTIRNPWTVAERAVMIESALPGETARLLVRPLRDH
LYNESLWIAEVQRQVAEAVHADGGTLDANIGLIGMDKDASSYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHG
GLLMLRGNVPAPVYDMLEAFRRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLW
ALPGGFVGQEEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAFHFEFPAGELPAVRGGDDADK
ARWIPLAEVMAMGPRLYEDHLHILEFFLGRG
>Mature_350_residues
ATPYHYLVFIGRFEPFHNGHAAVARHALGKAKKLIVLIGSADTPRTIRNPWTVAERAVMIESALPGETARLLVRPLRDHL
YNESLWIAEVQRQVAEAVHADGGTLDANIGLIGMDKDASSYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHGG
LLMLRGNVPAPVYDMLEAFRRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLWA
LPGGFVGQEEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAFHFEFPAGELPAVRGGDDADKA
RWIPLAEVMAMGPRLYEDHLHILEFFLGRG

Specific function: The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH [H]

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00293 NUDIX [H]

EC number: =2.7.7.1 [H]

Molecular weight: Translated: 39459; Mature: 39328

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPYHYLVFIGRFEPFHNGHAAVARHALGKAKKLIVLIGSADTPRTIRNPWTVAERAVM
CCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCHHHHHHHHH
IESALPGETARLLVRPLRDHLYNESLWIAEVQRQVAEAVHADGGTLDANIGLIGMDKDAS
HHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCC
SYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHGGLLMLRGNVPAPVYDMLEAF
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHH
RRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLW
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCEEEEEECCCCCCCEE
ALPGGFVGQEEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAF
ECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHCCCEEEEEE
HFEFPAGELPAVRGGDDADKARWIPLAEVMAMGPRLYEDHLHILEFFLGRG
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATPYHYLVFIGRFEPFHNGHAAVARHALGKAKKLIVLIGSADTPRTIRNPWTVAERAVM
CCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCHHHHHHHHH
IESALPGETARLLVRPLRDHLYNESLWIAEVQRQVAEAVHADGGTLDANIGLIGMDKDAS
HHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCC
SYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHGGLLMLRGNVPAPVYDMLEAF
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHH
RRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLW
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCEEEEEECCCCCCCEE
ALPGGFVGQEEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAF
ECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHCCCEEEEEE
HFEFPAGELPAVRGGDDADKARWIPLAEVMAMGPRLYEDHLHILEFFLGRG
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10050763 [H]