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The map label for this gene is msrB [H]

Identifier: 57237994

GI number: 57237994

Start: 1171582

End: 1171941

Strand: Reverse

Name: msrB [H]

Synonym: CJE1255

Alternate gene names: 57237994

Gene position: 1171941-1171582 (Counterclockwise)

Preceding gene: 57237996

Following gene: 57237993

Centisome position: 65.92

GC content: 30.56

Gene sequence:

>360_bases
ATGAAAGAATTAAATGAAGAAGAAAAAAAAGTAATTTTAAATAAAGGAACAGAAGCTCCTTTTAGTGGGAAATATAATGA
TTTTTATGAAAAAGGAATCTATCAATGCAAGCAATGTGGAGCTTCGCTTTATAAATCCGAAGATAAATTTAAATCAGGTT
GTGGATGGCCTAGCTTTGATGATGAAATAAAAGGGGCTGTTAAAAGAATTCCTGATAAAGATGGGATTAGAACCGAGATT
GTATGTGCAAATTGCAATGGACATTTAGGTCATGTTTTTGAAGGAGAAGGATTTTCTGCTAAAAATGTAAGACATTGTGT
AAATTCTATTTCTTTGGAATTTGTAAAAACTAAGGATTGA

Upstream 100 bases:

>100_bases
TCTTTTTGCATTTAAAACTTTCTTGAAAATTGTAAAAATTTATCATTTAAAATTGAAATTTTAATTATATAATATAAAAA
TTATTTTACAAGGGTAGATC

Downstream 100 bases:

>100_bases
TAGTGTTTTCTAGTATGGGTTCTGAGCTTTATTTGATGTTTTTTGCTGCAATTACTTTACTTGCTATATTAAATCCTTTT
GGTAATTTAACTCAATTTTT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MKELNEEEKKVILNKGTEAPFSGKYNDFYEKGIYQCKQCGASLYKSEDKFKSGCGWPSFDDEIKGAVKRIPDKDGIRTEI
VCANCNGHLGHVFEGEGFSAKNVRHCVNSISLEFVKTKD

Sequences:

>Translated_119_residues
MKELNEEEKKVILNKGTEAPFSGKYNDFYEKGIYQCKQCGASLYKSEDKFKSGCGWPSFDDEIKGAVKRIPDKDGIRTEI
VCANCNGHLGHVFEGEGFSAKNVRHCVNSISLEFVKTKD
>Mature_119_residues
MKELNEEEKKVILNKGTEAPFSGKYNDFYEKGIYQCKQCGASLYKSEDKFKSGCGWPSFDDEIKGAVKRIPDKDGIRTEI
VCANCNGHLGHVFEGEGFSAKNVRHCVNSISLEFVKTKD

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI117606353, Length=127, Percent_Identity=41.7322834645669, Blast_Score=94, Evalue=2e-20,
Organism=Homo sapiens, GI37620216, Length=117, Percent_Identity=41.025641025641, Blast_Score=92, Evalue=7e-20,
Organism=Homo sapiens, GI301336164, Length=117, Percent_Identity=41.025641025641, Blast_Score=92, Evalue=8e-20,
Organism=Homo sapiens, GI301336162, Length=117, Percent_Identity=41.025641025641, Blast_Score=92, Evalue=8e-20,
Organism=Homo sapiens, GI73089054, Length=117, Percent_Identity=41.025641025641, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788077, Length=117, Percent_Identity=43.5897435897436, Blast_Score=93, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17553450, Length=117, Percent_Identity=41.025641025641, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115532676, Length=117, Percent_Identity=41.025641025641, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319816, Length=121, Percent_Identity=44.6280991735537, Blast_Score=100, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24645799, Length=120, Percent_Identity=49.1666666666667, Blast_Score=115, Evalue=5e-27,
Organism=Drosophila melanogaster, GI45553335, Length=120, Percent_Identity=49.1666666666667, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21356369, Length=120, Percent_Identity=49.1666666666667, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24645801, Length=129, Percent_Identity=44.9612403100775, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24645804, Length=129, Percent_Identity=44.9612403100775, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221378664, Length=120, Percent_Identity=45.8333333333333, Blast_Score=109, Evalue=3e-25,
Organism=Drosophila melanogaster, GI221378662, Length=127, Percent_Identity=43.3070866141732, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 13361; Mature: 13361

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELNEEEKKVILNKGTEAPFSGKYNDFYEKGIYQCKQCGASLYKSEDKFKSGCGWPSFD
CCCCCCHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
DEIKGAVKRIPDKDGIRTEIVCANCNGHLGHVFEGEGFSAKNVRHCVNSISLEFVKTKD
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHCEEEEECCC
>Mature Secondary Structure
MKELNEEEKKVILNKGTEAPFSGKYNDFYEKGIYQCKQCGASLYKSEDKFKSGCGWPSFD
CCCCCCHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
DEIKGAVKRIPDKDGIRTEIVCANCNGHLGHVFEGEGFSAKNVRHCVNSISLEFVKTKD
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA