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The map label for this gene is kdsB [H]

Identifier: 57237658

GI number: 57237658

Start: 842944

End: 843663

Strand: Direct

Name: kdsB [H]

Synonym: CJE0904

Alternate gene names: 57237658

Gene position: 842944-843663 (Clockwise)

Preceding gene: 57237657

Following gene: 57237659

Centisome position: 47.41

GC content: 30.42

Gene sequence:

>720_bases
ATGATTATTATCCCTGCAAGATTAAAATCAAGTCGTTTTCATGAGAAAATTTTATGTGATGTAGGTGGAGTGCCTATGTT
TGTGGCTACTGCAAGAAGGGTAAGTAGTGTGGATGAAGTTTGTATAGCTTTAGATGATGAAAAGGTTTTAAGTATCGCTA
AAGAATATGGTTTAAATGCAGTTTTAACAAGCAAAAATCATGAAAGCGGTACGGATAGGATTAATGAAGCTTGTAAGAAA
CTATCTTTAAAAGATGATGAGATTATTATCAATGTCCAAGCTGATGAGCCTTTTATAGAATGTGAAAATTTATTAAAATT
TAAAGAATTTGCAAGTTCTTGCTTGGATAAAAAAGCTTTTATGGCGAGTTGTTATAAAAAAATCACTCAAGAAGAAGCTA
TGGATTCTAATTTGGTTAAAGTGCTTTGCGATAAAGAAGGATATGCTTTGTATTTTTCAAGAGCTAAAATCCCTTATGAA
AGAGAAAATTACGAGGAAAGTTTTAAAGGGCATTTAGGCATTTATGCTTATAGTGTAAAAGCTTTAAGAGAGTTTTGTTC
TTTATTAAGTTCTGCACTTGAAAGAGCGGAAAAATTAGAGCAATTAAGAGCTATAGAAAATGGTAAAAAAATCAAAATGC
TTGAAATTTCAACAACAAGCATGGGGATTGATACCAAAGAAGACTATGAAAAGGCTTTAAAAATTTATTTAGAAAAATAA

Upstream 100 bases:

>100_bases
TTAAAGATGAAATTTTGGCTTTATTTGACTTGAAAAATAGCGATGAAAAGGTATTTGAAGCCAAAAATATAAAAAAAGAA
ATTTTAGATTGGATGCAAAA

Downstream 100 bases:

>100_bases
CTCCACCCCAAAACGGAACAGATTTTGCTTATATTATTTTAATATATTTAGATTGAAGGCAGAAAAATCTAAATCAAGGA
ATTAATATGAGTATCTTTAG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MIIIPARLKSSRFHEKILCDVGGVPMFVATARRVSSVDEVCIALDDEKVLSIAKEYGLNAVLTSKNHESGTDRINEACKK
LSLKDDEIIINVQADEPFIECENLLKFKEFASSCLDKKAFMASCYKKITQEEAMDSNLVKVLCDKEGYALYFSRAKIPYE
RENYEESFKGHLGIYAYSVKALREFCSLLSSALERAEKLEQLRAIENGKKIKMLEISTTSMGIDTKEDYEKALKIYLEK

Sequences:

>Translated_239_residues
MIIIPARLKSSRFHEKILCDVGGVPMFVATARRVSSVDEVCIALDDEKVLSIAKEYGLNAVLTSKNHESGTDRINEACKK
LSLKDDEIIINVQADEPFIECENLLKFKEFASSCLDKKAFMASCYKKITQEEAMDSNLVKVLCDKEGYALYFSRAKIPYE
RENYEESFKGHLGIYAYSVKALREFCSLLSSALERAEKLEQLRAIENGKKIKMLEISTTSMGIDTKEDYEKALKIYLEK
>Mature_239_residues
MIIIPARLKSSRFHEKILCDVGGVPMFVATARRVSSVDEVCIALDDEKVLSIAKEYGLNAVLTSKNHESGTDRINEACKK
LSLKDDEIIINVQADEPFIECENLLKFKEFASSCLDKKAFMASCYKKITQEEAMDSNLVKVLCDKEGYALYFSRAKIPYE
RENYEESFKGHLGIYAYSVKALREFCSLLSSALERAEKLEQLRAIENGKKIKMLEISTTSMGIDTKEDYEKALKIYLEK

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=242, Percent_Identity=37.603305785124, Blast_Score=164, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27129; Mature: 27129

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIPARLKSSRFHEKILCDVGGVPMFVATARRVSSVDEVCIALDDEKVLSIAKEYGLNA
CEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHCCCE
VLTSKNHESGTDRINEACKKLSLKDDEIIINVQADEPFIECENLLKFKEFASSCLDKKAF
EEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
MASCYKKITQEEAMDSNLVKVLCDKEGYALYFSRAKIPYERENYEESFKGHLGIYAYSVK
HHHHHHHHHHHHHHCCHHHHEEECCCCCEEEEECCCCCCCCCCHHHHHCCCHHHHHHHHH
ALREFCSLLSSALERAEKLEQLRAIENGKKIKMLEISTTSMGIDTKEDYEKALKIYLEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIIPARLKSSRFHEKILCDVGGVPMFVATARRVSSVDEVCIALDDEKVLSIAKEYGLNA
CEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHCCCE
VLTSKNHESGTDRINEACKKLSLKDDEIIINVQADEPFIECENLLKFKEFASSCLDKKAF
EEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
MASCYKKITQEEAMDSNLVKVLCDKEGYALYFSRAKIPYERENYEESFKGHLGIYAYSVK
HHHHHHHHHHHHHHCCHHHHEEECCCCCEEEEECCCCCCCCCCHHHHHCCCHHHHHHHHH
ALREFCSLLSSALERAEKLEQLRAIENGKKIKMLEISTTSMGIDTKEDYEKALKIYLEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]