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The map label for this gene is lpxK [H]

Identifier: 57237656

GI number: 57237656

Start: 840612

End: 841538

Strand: Direct

Name: lpxK [H]

Synonym: CJE0902

Alternate gene names: 57237656

Gene position: 840612-841538 (Clockwise)

Preceding gene: 57237655

Following gene: 57237657

Centisome position: 47.28

GC content: 28.26

Gene sequence:

>927_bases
ATGAATGAAGAAAAAAATTATGAACTTTGGCTTGATAATTATTTTTTTAAGCCCAATTTTTGGCAAAAATGCCTTGCTTT
TATACTTTTACCTTTAAGTGTGCTTTATGCTTTTTTTGCGATTTTAAATACTTTTTTTCGTAAAAAAATAGTTTTTAAAA
AGCCTGTTATTAGCGTTGGTAATTTAAGTTTTGGAGGTAATGGAAAAACCCCGCTTTGTAAAGCTATAGCAAGGGAATTT
GATGGCGTTTTTATAGTACTTAGGGGCTATAAAAGAAAGTCTAAAGGTTTGTTTGTTGTTAAAAATCAAAATGAAATTTT
ATGCACCTTAGTACAAAGTGGCGATGAAGCTATGGAGTATGCTTTTGAAGAAAATATCAAAGGTGTGATTGTGAGTGAAG
ATAGAGTAAAAGGTATTGAAAAAGCCTTTGAATTGGGAGCTAAAATCGTTGTACTCGATGATGCTTTTTCTAAATTTCAT
ATTAAAAAATTTGATATTTTGCTTGAAAGCAAAATCAAACCTTATTTTGATTTTACTTTACCAAGTGGAGCTTATCGTTT
GCCAAAATTTTATGAAAAAAGGGCTGATTTTATTGCATTAGAAGGCAGGGATTTTGTGCGTTATTCTTTTGTAAAAGAAA
ATCCAAAGGCTGTTTTGGCAACTGCTATTGCTAAACCTTTTAGATTGTATGAGCATTTTATCAAAGCAAGGGCTTGTTAT
TTTTTTAAAGATCATTATGAGTTTAAAAAAGAAGAATTAGAAAATTTGCTAAAAAAACATAATTGCGATACACTAATGCT
TACTTTTAAGGATTTTGTTAAAGTTAAAGATTTTGGTTTTAAATGTCAAATTATAGAATTAAATATAGAATTAAAAGATT
CATTAAGGGAAAAAATAAAAACTTATATCAAGGAGTTTGAGCAATGA

Upstream 100 bases:

>100_bases
TTTAAGAACGCTTGATCCTTCTTTGATTGCTATGTTAAAAAATCGCATGCAAAAAAATGCTTTTAAGGGAAAAATGCCTG
AAATTTTGGAAATTTAAACA

Downstream 100 bases:

>100_bases
AATTAGTCGAGAGTAGAAATGTAAATAATGTATCAAGTTTTAAGGAAGCTTTGATTAACCCAAACGCCCCAGAAGGAGGG
CTTTACTCGCCTTTAAATTT

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNEEKNYELWLDNYFFKPNFWQKCLAFILLPLSVLYAFFAILNTFFRKKIVFKKPVISVGNLSFGGNGKTPLCKAIAREF
DGVFIVLRGYKRKSKGLFVVKNQNEILCTLVQSGDEAMEYAFEENIKGVIVSEDRVKGIEKAFELGAKIVVLDDAFSKFH
IKKFDILLESKIKPYFDFTLPSGAYRLPKFYEKRADFIALEGRDFVRYSFVKENPKAVLATAIAKPFRLYEHFIKARACY
FFKDHYEFKKEELENLLKKHNCDTLMLTFKDFVKVKDFGFKCQIIELNIELKDSLREKIKTYIKEFEQ

Sequences:

>Translated_308_residues
MNEEKNYELWLDNYFFKPNFWQKCLAFILLPLSVLYAFFAILNTFFRKKIVFKKPVISVGNLSFGGNGKTPLCKAIAREF
DGVFIVLRGYKRKSKGLFVVKNQNEILCTLVQSGDEAMEYAFEENIKGVIVSEDRVKGIEKAFELGAKIVVLDDAFSKFH
IKKFDILLESKIKPYFDFTLPSGAYRLPKFYEKRADFIALEGRDFVRYSFVKENPKAVLATAIAKPFRLYEHFIKARACY
FFKDHYEFKKEELENLLKKHNCDTLMLTFKDFVKVKDFGFKCQIIELNIELKDSLREKIKTYIKEFEQ
>Mature_308_residues
MNEEKNYELWLDNYFFKPNFWQKCLAFILLPLSVLYAFFAILNTFFRKKIVFKKPVISVGNLSFGGNGKTPLCKAIAREF
DGVFIVLRGYKRKSKGLFVVKNQNEILCTLVQSGDEAMEYAFEENIKGVIVSEDRVKGIEKAFELGAKIVVLDDAFSKFH
IKKFDILLESKIKPYFDFTLPSGAYRLPKFYEKRADFIALEGRDFVRYSFVKENPKAVLATAIAKPFRLYEHFIKARACY
FFKDHYEFKKEELENLLKKHNCDTLMLTFKDFVKVKDFGFKCQIIELNIELKDSLREKIKTYIKEFEQ

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 36199; Mature: 36199

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEEKNYELWLDNYFFKPNFWQKCLAFILLPLSVLYAFFAILNTFFRKKIVFKKPVISVG
CCCCCCEEEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NLSFGGNGKTPLCKAIAREFDGVFIVLRGYKRKSKGLFVVKNQNEILCTLVQSGDEAMEY
CEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCHHHHH
AFEENIKGVIVSEDRVKGIEKAFELGAKIVVLDDAFSKFHIKKFDILLESKIKPYFDFTL
HHHCCCCEEEEEHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEC
PSGAYRLPKFYEKRADFIALEGRDFVRYSFVKENPKAVLATAIAKPFRLYEHFIKARACY
CCCCCCCHHHHHCCCCEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FFKDHYEFKKEELENLLKKHNCDTLMLTFKDFVKVKDFGFKCQIIELNIELKDSLREKIK
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCEEEEEEEEEEHHHHHHHHHH
TYIKEFEQ
HHHHHHCC
>Mature Secondary Structure
MNEEKNYELWLDNYFFKPNFWQKCLAFILLPLSVLYAFFAILNTFFRKKIVFKKPVISVG
CCCCCCEEEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NLSFGGNGKTPLCKAIAREFDGVFIVLRGYKRKSKGLFVVKNQNEILCTLVQSGDEAMEY
CEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCHHHHH
AFEENIKGVIVSEDRVKGIEKAFELGAKIVVLDDAFSKFHIKKFDILLESKIKPYFDFTL
HHHCCCCEEEEEHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEC
PSGAYRLPKFYEKRADFIALEGRDFVRYSFVKENPKAVLATAIAKPFRLYEHFIKARACY
CCCCCCCHHHHHCCCCEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FFKDHYEFKKEELENLLKKHNCDTLMLTFKDFVKVKDFGFKCQIIELNIELKDSLREKIK
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCEEEEEEEEEEHHHHHHHHHH
TYIKEFEQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA