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The map label for this gene is hrcA [H]

Identifier: 57237602

GI number: 57237602

Start: 786287

End: 787081

Strand: Direct

Name: hrcA [H]

Synonym: CJE0848

Alternate gene names: 57237602

Gene position: 786287-787081 (Clockwise)

Preceding gene: 57237601

Following gene: 57237603

Centisome position: 44.23

GC content: 29.94

Gene sequence:

>795_bases
ATGATGAAAAGTCGAGATAAAAAGGATTTGATTTTAGAGTCTATTATCCAAACTTATCTTTTGGATAATGCGCCTATTGG
TTCTAATGAATTAAATTCAAACCTTTGTATACCTGCTTCGACTATACGCGTTTATCTTAAAAGACTTAGCGATGAGGGTT
TGATCACTCAGCTTCATATAAGTAGTGGTAGAATTCCTACTATTTTAACGATGCAAAATTATTGGCAAAGTTTTTGGGAA
AAAGAACAAGATAAAAATATCCATATCAAAAACGAAAGCTTTTTGAAAGAGTTAAGTAAAGAATTTGAAATTTATTGTCT
TGTTTATGGAGGTAGAAGTTTAGTACTTAAAGAAGTACTAGATCTTAATACTAAATTTATAGTGCTTGATTTTGAAGATG
AAGAGCTGGTTTTAAAATACGAAAAAGAAGCGTGGAATTTTTTACAAAGTCTTATAGGGCTTGATCTTTCTAGTATAGAA
AAAATAGCTTTGAGAGTTCATTTTATAGATCTTGTAGAAAAAATAGCTAGCTTAAGACAAAATTTGATTTGCTATAGAAG
CAATGAAGAAAGAGCTTATCAAATTTATCAAAATGATGAATTTGTTAAGCTCTTAGATTGTCAAATTCACCGTCATTTTA
AAGAAAGTCTTGAATTTGAACCTTTATTTAAAGAAGGTTTTATGGGGCTTAAGGTAGATGCGCAGTTTTTGGGCGAAGAT
GTAAATATTATCTTAGCAGGTAGTGTTTATACGGATTATAAAAAGATATTACAATACATAAAGGAGGCGGCATGA

Upstream 100 bases:

>100_bases
TTAAGTATATTTTTTTATATTTATACTTGACAAAATAACACTCAATGTTGTATAATATATCTAGCAATCAAAAAATAGAG
TGCTAGATATAAAGGAAAAC

Downstream 100 bases:

>100_bases
GCGAACAAAAGCAAGAAATTGAAAATGAAAATGCACAAAATTCTGAAAATTTACAGGATGATTTGCAAGATAATGAAAAA
AACGAAACAAATGAATTACA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MMKSRDKKDLILESIIQTYLLDNAPIGSNELNSNLCIPASTIRVYLKRLSDEGLITQLHISSGRIPTILTMQNYWQSFWE
KEQDKNIHIKNESFLKELSKEFEIYCLVYGGRSLVLKEVLDLNTKFIVLDFEDEELVLKYEKEAWNFLQSLIGLDLSSIE
KIALRVHFIDLVEKIASLRQNLICYRSNEERAYQIYQNDEFVKLLDCQIHRHFKESLEFEPLFKEGFMGLKVDAQFLGED
VNIILAGSVYTDYKKILQYIKEAA

Sequences:

>Translated_264_residues
MMKSRDKKDLILESIIQTYLLDNAPIGSNELNSNLCIPASTIRVYLKRLSDEGLITQLHISSGRIPTILTMQNYWQSFWE
KEQDKNIHIKNESFLKELSKEFEIYCLVYGGRSLVLKEVLDLNTKFIVLDFEDEELVLKYEKEAWNFLQSLIGLDLSSIE
KIALRVHFIDLVEKIASLRQNLICYRSNEERAYQIYQNDEFVKLLDCQIHRHFKESLEFEPLFKEGFMGLKVDAQFLGED
VNIILAGSVYTDYKKILQYIKEAA
>Mature_264_residues
MMKSRDKKDLILESIIQTYLLDNAPIGSNELNSNLCIPASTIRVYLKRLSDEGLITQLHISSGRIPTILTMQNYWQSFWE
KEQDKNIHIKNESFLKELSKEFEIYCLVYGGRSLVLKEVLDLNTKFIVLDFEDEELVLKYEKEAWNFLQSLIGLDLSSIE
KIALRVHFIDLVEKIASLRQNLICYRSNEERAYQIYQNDEFVKLLDCQIHRHFKESLEFEPLFKEGFMGLKVDAQFLGED
VNIILAGSVYTDYKKILQYIKEAA

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30908; Mature: 30908

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKSRDKKDLILESIIQTYLLDNAPIGSNELNSNLCIPASTIRVYLKRLSDEGLITQLHI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE
SSGRIPTILTMQNYWQSFWEKEQDKNIHIKNESFLKELSKEFEIYCLVYGGRSLVLKEVL
CCCCCCEEEEHHHHHHHHHCCCCCCCEEECCHHHHHHHHHCCEEEEEEECCHHHHHHHHH
DLNTKFIVLDFEDEELVLKYEKEAWNFLQSLIGLDLSSIEKIALRVHFIDLVEKIASLRQ
CCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLICYRSNEERAYQIYQNDEFVKLLDCQIHRHFKESLEFEPLFKEGFMGLKVDAQFLGED
CEEEEECCCCCEEEEECCCCEEHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEHHHCCCC
VNIILAGSVYTDYKKILQYIKEAA
CEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKSRDKKDLILESIIQTYLLDNAPIGSNELNSNLCIPASTIRVYLKRLSDEGLITQLHI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE
SSGRIPTILTMQNYWQSFWEKEQDKNIHIKNESFLKELSKEFEIYCLVYGGRSLVLKEVL
CCCCCCEEEEHHHHHHHHHCCCCCCCEEECCHHHHHHHHHCCEEEEEEECCHHHHHHHHH
DLNTKFIVLDFEDEELVLKYEKEAWNFLQSLIGLDLSSIEKIALRVHFIDLVEKIASLRQ
CCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLICYRSNEERAYQIYQNDEFVKLLDCQIHRHFKESLEFEPLFKEGFMGLKVDAQFLGED
CEEEEECCCCCEEEEECCCCEEHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEHHHCCCC
VNIILAGSVYTDYKKILQYIKEAA
CEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]