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The map label for this gene is radA [H]

Identifier: 21226559

GI number: 21226559

Start: 578452

End: 579555

Strand: Reverse

Name: radA [H]

Synonym: MM_0457

Alternate gene names: 21226559

Gene position: 579555-578452 (Counterclockwise)

Preceding gene: 21226563

Following gene: 21226558

Centisome position: 14.15

GC content: 49.0

Gene sequence:

>1104_bases
TTGGCGCAATTTTTAGCGGTTAAGAATACTTTCACCCCGCCTACTCTAGTTATATATACGTGCAAAACCATAGTTGAGCC
ACTGTCATGCACCTTATACAAACATGTGCATCTAGGAGAATTTGTAATGAGCGAAATAGCACTCGAAGAACTGCCAGGAG
TTGGCCCTGCTACTGCAGAAAAACTCAAGGAAGCCGGATTTAACACAATTGAAGCAGTCGCTGTAGCGTCTCCTTCTGAA
CTTGCAACCACAGCCGAAATCGGGGAATCGACTGCCGCAAAAATCATTAATGCCGCAAGACAGGCTGCTGATATAGGGGG
GTTTGAGACCGGAGATCTCGTCCTTGAAAGAAGGAAGCTTGTAGGCAAACTTACCACCGGTTGCACCGAATTTGATGAAA
TGATGGGTGGAGGTATCGAAACTCAGGCTATTACCGAACTCTACGGAGAATTCGGTTCCGGAAAGACGCAGGTGGCTCAC
CAGCTTGCAGTAAATGTCCAGATGGACAGGGAACACGGAGGTCTCGGCGGTTCCGTCATTATTATCGACACTGAAAATAC
CTTCAGGCCGGAAAGGATCACCCAGATGGTAAACGGGCTTTCCGAGAAGTACGGAATGGAACTTAATCCCGAAGAATTCC
TGCAGAACATCCATGTAGCGAGAGCTTACAATTCCAATCATCAGATACTTCTTGTTGACTCTGCTGTGGACCTGGCAAAC
GAACTCAAGGAAATGGGCAAACCCGTTCGCCTCTTAATTGTTGACTCCCTTATGGCTCACTTCAGGGCTGAGTATGTCGG
AAGAGGAACCCTTGCAGACAGGCAGCAGAAACTCAACAAACACATGCACGGCCTTCTCCGCTTCGGAGACCTGTTCAACG
CCTGTGTTGTTGTTACAAACCAGGTTATGGCAAAGCCCGATGCCTTCTTTGGAGACCCCACAAGGCCAATCGGAGGGCAC
ATAGTCGGGCACACGGCAACCTTCAGGCTTTACCTGAGGAAATCCAAAGGAGAAAAGAGAATTATACGCCTCGTTGACTC
GCCCAGCCTCCCGGAAGGAGAAGCTGTTGTTGCAGTAACCACAGCTGGGCTTACTGACCAGTAA

Upstream 100 bases:

>100_bases
TTCTATATTTTTTTCTCTCTTTTCCTCTTTTCTTTTACAAGTTTAAGTGGCTGAAAAGAGCTCTTTTTATCCACTTTTTT
GCCAGGTTCTTTCGAGTAAA

Downstream 100 bases:

>100_bases
ACCTGGAATCAAACTCTGATCAAAATACAATCAGAATACGATCAGGATACGATTAGAATACGATTAAAATAAGATTAGAA
TAAGTAAGGATCTGTGATCA

Product: DNA repair and recombination protein RadA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MAQFLAVKNTFTPPTLVIYTCKTIVEPLSCTLYKHVHLGEFVMSEIALEELPGVGPATAEKLKEAGFNTIEAVAVASPSE
LATTAEIGESTAAKIINAARQAADIGGFETGDLVLERRKLVGKLTTGCTEFDEMMGGGIETQAITELYGEFGSGKTQVAH
QLAVNVQMDREHGGLGGSVIIIDTENTFRPERITQMVNGLSEKYGMELNPEEFLQNIHVARAYNSNHQILLVDSAVDLAN
ELKEMGKPVRLLIVDSLMAHFRAEYVGRGTLADRQQKLNKHMHGLLRFGDLFNACVVVTNQVMAKPDAFFGDPTRPIGGH
IVGHTATFRLYLRKSKGEKRIIRLVDSPSLPEGEAVVAVTTAGLTDQ

Sequences:

>Translated_367_residues
MAQFLAVKNTFTPPTLVIYTCKTIVEPLSCTLYKHVHLGEFVMSEIALEELPGVGPATAEKLKEAGFNTIEAVAVASPSE
LATTAEIGESTAAKIINAARQAADIGGFETGDLVLERRKLVGKLTTGCTEFDEMMGGGIETQAITELYGEFGSGKTQVAH
QLAVNVQMDREHGGLGGSVIIIDTENTFRPERITQMVNGLSEKYGMELNPEEFLQNIHVARAYNSNHQILLVDSAVDLAN
ELKEMGKPVRLLIVDSLMAHFRAEYVGRGTLADRQQKLNKHMHGLLRFGDLFNACVVVTNQVMAKPDAFFGDPTRPIGGH
IVGHTATFRLYLRKSKGEKRIIRLVDSPSLPEGEAVVAVTTAGLTDQ
>Mature_366_residues
AQFLAVKNTFTPPTLVIYTCKTIVEPLSCTLYKHVHLGEFVMSEIALEELPGVGPATAEKLKEAGFNTIEAVAVASPSEL
ATTAEIGESTAAKIINAARQAADIGGFETGDLVLERRKLVGKLTTGCTEFDEMMGGGIETQAITELYGEFGSGKTQVAHQ
LAVNVQMDREHGGLGGSVIIIDTENTFRPERITQMVNGLSEKYGMELNPEEFLQNIHVARAYNSNHQILLVDSAVDLANE
LKEMGKPVRLLIVDSLMAHFRAEYVGRGTLADRQQKLNKHMHGLLRFGDLFNACVVVTNQVMAKPDAFFGDPTRPIGGHI
VGHTATFRLYLRKSKGEKRIIRLVDSPSLPEGEAVVAVTTAGLTDQ

Specific function: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules [H]

COG id: COG0468

COG function: function code L; RecA/RadA recombinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic recA-like protein family [H]

Homologues:

Organism=Homo sapiens, GI19924133, Length=320, Percent_Identity=43.75, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI23238219, Length=330, Percent_Identity=41.2121212121212, Blast_Score=244, Evalue=7e-65,
Organism=Homo sapiens, GI256017143, Length=323, Percent_Identity=41.7956656346749, Blast_Score=228, Evalue=9e-60,
Organism=Homo sapiens, GI256017141, Length=323, Percent_Identity=41.7956656346749, Blast_Score=228, Evalue=9e-60,
Organism=Homo sapiens, GI256017145, Length=241, Percent_Identity=41.49377593361, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI17402896, Length=337, Percent_Identity=29.673590504451, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI153946430, Length=263, Percent_Identity=26.9961977186312, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4885659, Length=263, Percent_Identity=26.9961977186312, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI153946427, Length=263, Percent_Identity=26.9961977186312, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19924117, Length=271, Percent_Identity=26.1992619926199, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI46255039, Length=271, Percent_Identity=26.1992619926199, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI10835029, Length=271, Percent_Identity=26.1992619926199, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71997295, Length=310, Percent_Identity=42.9032258064516, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI71997301, Length=310, Percent_Identity=42.9032258064516, Blast_Score=241, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6321027, Length=327, Percent_Identity=41.8960244648318, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6320942, Length=337, Percent_Identity=41.5430267062315, Blast_Score=230, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320207, Length=189, Percent_Identity=31.7460317460317, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17864108, Length=307, Percent_Identity=42.671009771987, Blast_Score=231, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24651285, Length=282, Percent_Identity=43.6170212765958, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI17136506, Length=260, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24650551, Length=140, Percent_Identity=34.2857142857143, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013632
- InterPro:   IPR011938
- InterPro:   IPR016467
- InterPro:   IPR020588
- InterPro:   IPR010995
- InterPro:   IPR003583
- InterPro:   IPR020587 [H]

Pfam domain/function: PF08423 Rad51 [H]

EC number: NA

Molecular weight: Translated: 39863; Mature: 39732

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50162 RECA_2 ; PS50163 RECA_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFLAVKNTFTPPTLVIYTCKTIVEPLSCTLYKHVHLGEFVMSEIALEELPGVGPATAE
CCCEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KLKEAGFNTIEAVAVASPSELATTAEIGESTAAKIINAARQAADIGGFETGDLVLERRKL
HHHHCCCCHHHHEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VGKLTTGCTEFDEMMGGGIETQAITELYGEFGSGKTQVAHQLAVNVQMDREHGGLGGSVI
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCCCEEE
IIDTENTFRPERITQMVNGLSEKYGMELNPEEFLQNIHVARAYNSNHQILLVDSAVDLAN
EEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCEEEEEECHHHHHH
ELKEMGKPVRLLIVDSLMAHFRAEYVGRGTLADRQQKLNKHMHGLLRFGDLFNACVVVTN
HHHHHCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVMAKPDAFFGDPTRPIGGHIVGHTATFRLYLRKSKGEKRIIRLVDSPSLPEGEAVVAVT
HHHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEEEE
TAGLTDQ
ECCCCCC
>Mature Secondary Structure 
AQFLAVKNTFTPPTLVIYTCKTIVEPLSCTLYKHVHLGEFVMSEIALEELPGVGPATAE
CCEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KLKEAGFNTIEAVAVASPSELATTAEIGESTAAKIINAARQAADIGGFETGDLVLERRKL
HHHHCCCCHHHHEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VGKLTTGCTEFDEMMGGGIETQAITELYGEFGSGKTQVAHQLAVNVQMDREHGGLGGSVI
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCCCEEE
IIDTENTFRPERITQMVNGLSEKYGMELNPEEFLQNIHVARAYNSNHQILLVDSAVDLAN
EEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCEEEEEECHHHHHH
ELKEMGKPVRLLIVDSLMAHFRAEYVGRGTLADRQQKLNKHMHGLLRFGDLFNACVVVTN
HHHHHCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVMAKPDAFFGDPTRPIGGHIVGHTATFRLYLRKSKGEKRIIRLVDSPSLPEGEAVVAVT
HHHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEEEE
TAGLTDQ
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]