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The map label for this gene is hss [H]

Identifier: 21226268

GI number: 21226268

Start: 215609

End: 217057

Strand: Direct

Name: hss [H]

Synonym: MM_0166

Alternate gene names: 21226268

Gene position: 215609-217057 (Clockwise)

Preceding gene: 21226266

Following gene: 21226269

Centisome position: 5.26

GC content: 46.24

Gene sequence:

>1449_bases
ATGAAAAAAAGATTTTCCAATAAAGTCCTGATTATTGGTTATGGTTCAGTTTCACAGTGCACCCTGCCCCTTTTACTGGA
TAAGCTCGATATCCCGCTTGAAAACATCACCTTAATTGATTTTGAAGACAAGTCAAAAGCCCTGAAAAAGTATACTAATC
AGGGATTAACGTTTGTCCGTGAAAAGATTACCCCGGAAAATCTGGATCAGGTTCTGTCACAAAATATGGAAAATGAAGGA
ATGATCATTGATCTTTCGTGGAATATCGATGCCAACGAAATCGTCAAGTGGTGCCATGACCACGATGTACTGTACGTTAA
TACTTCGGTAGAAGTATGGGACCCTGCTGAGAAATTTCTGACTCAAAGTTTATTGGAAAAATCTCTTTATTTACGGCAAA
TGAGACTGCAGGAACTTTCCCGCGACTGGAAAGATGCTCCGACTGCTGTTGTTGACCATGGAGCAAATCCGGGCCTGATA
ACTCACTTCGTAAAGCAGGGCTTGCTGGATATTGCCGCCCGCACCTGTGAAGACAAAAAAGTATCACCCGAAGACGAACA
GGAAATTGCCCTCCTTGCAAAAAACAGGGACTTTGCCCGCCTGGCCCGGAAGCTGGGAATCAGGGTGATCCACTGCAGCG
AAAGGGATACTCAAATTGCCAGCCGGCCAAAGGAAGTTAATGAATTTGTAGGAACATGGAGCATTGAAGGATTAAGAGAA
GAAGGAACTGCTCCGGTTGAAATAGCCTGGGGCACCCATGAGAGCAAATTGCCTCCCCTCGCACATATACCTCCCTACGG
ACCGAAAAATGTAATTCTCCTTCCTCAGATGGGCGTTAATGCATGGGTCAGGTCGTGGATACCTGACGAAGAAATTGTAG
GTATGGCTATCCGTCACGGAGAATCATATGGCCTTTCAAAACTGCTAACTGTCTGGGAAGGTGAAAAAGCGGTATATCGC
CCCACAGTACATTATGCTTACATGCCCTCTCATGATACCCTTTCCTCTCTTTGCGAATTGCGTGGCAGGAATTATGAGCT
TCAACCCAGGCTCAGGATCATGACAAATGAAATCGTATCTGGCGAAGATATAATGGGAGCACTCCTGATGGGTCACTCTT
ATAATTCCTGGTGGACCGGGAGTGCGTTGAGCATTGAAGAGGCAAGGTCCCTCGCTCCCGGCCAGAATGCTACAACTCTT
CAGGTAGCTGCAGGCATTGTTGCTGCCATACTATGGATGCTTGAAAACCCGCGGGAAGGCGTTAAAACACCTGAGGACCT
GCCCCATGATTTTGTCCTGGATATTGCCAGACCGTACCTCGGGAAATTTATTTCGACACCTTCGGACTGGACACCACTCA
AAAACCGCAAAATATTTTTCAAAGAAAGCCCCGCCGTGAAGCACGACCCGGACCCATGGCAATTTGAGAATTTTATTTTC
GTAGGTTAA

Upstream 100 bases:

>100_bases
ATCCCATGAACCTCCACCAGAGTTTGGAGAAATCAGGTAGCATTATTGAGAGAAGTTAATATGAGAAAAGTTATATTCAT
GTCTCACGTTTACGAATCCT

Downstream 100 bases:

>100_bases
TCCGGAGTGAGATATTCCAGGTAAACCCTTTCCAGAGCAGACTGATCAGAGCAGACTGATATCTGGCCCTGGAGGGAGCT
TACCTGATTTCTGCGTTAAA

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MKKRFSNKVLIIGYGSVSQCTLPLLLDKLDIPLENITLIDFEDKSKALKKYTNQGLTFVREKITPENLDQVLSQNMENEG
MIIDLSWNIDANEIVKWCHDHDVLYVNTSVEVWDPAEKFLTQSLLEKSLYLRQMRLQELSRDWKDAPTAVVDHGANPGLI
THFVKQGLLDIAARTCEDKKVSPEDEQEIALLAKNRDFARLARKLGIRVIHCSERDTQIASRPKEVNEFVGTWSIEGLRE
EGTAPVEIAWGTHESKLPPLAHIPPYGPKNVILLPQMGVNAWVRSWIPDEEIVGMAIRHGESYGLSKLLTVWEGEKAVYR
PTVHYAYMPSHDTLSSLCELRGRNYELQPRLRIMTNEIVSGEDIMGALLMGHSYNSWWTGSALSIEEARSLAPGQNATTL
QVAAGIVAAILWMLENPREGVKTPEDLPHDFVLDIARPYLGKFISTPSDWTPLKNRKIFFKESPAVKHDPDPWQFENFIF
VG

Sequences:

>Translated_482_residues
MKKRFSNKVLIIGYGSVSQCTLPLLLDKLDIPLENITLIDFEDKSKALKKYTNQGLTFVREKITPENLDQVLSQNMENEG
MIIDLSWNIDANEIVKWCHDHDVLYVNTSVEVWDPAEKFLTQSLLEKSLYLRQMRLQELSRDWKDAPTAVVDHGANPGLI
THFVKQGLLDIAARTCEDKKVSPEDEQEIALLAKNRDFARLARKLGIRVIHCSERDTQIASRPKEVNEFVGTWSIEGLRE
EGTAPVEIAWGTHESKLPPLAHIPPYGPKNVILLPQMGVNAWVRSWIPDEEIVGMAIRHGESYGLSKLLTVWEGEKAVYR
PTVHYAYMPSHDTLSSLCELRGRNYELQPRLRIMTNEIVSGEDIMGALLMGHSYNSWWTGSALSIEEARSLAPGQNATTL
QVAAGIVAAILWMLENPREGVKTPEDLPHDFVLDIARPYLGKFISTPSDWTPLKNRKIFFKESPAVKHDPDPWQFENFIF
VG
>Mature_482_residues
MKKRFSNKVLIIGYGSVSQCTLPLLLDKLDIPLENITLIDFEDKSKALKKYTNQGLTFVREKITPENLDQVLSQNMENEG
MIIDLSWNIDANEIVKWCHDHDVLYVNTSVEVWDPAEKFLTQSLLEKSLYLRQMRLQELSRDWKDAPTAVVDHGANPGLI
THFVKQGLLDIAARTCEDKKVSPEDEQEIALLAKNRDFARLARKLGIRVIHCSERDTQIASRPKEVNEFVGTWSIEGLRE
EGTAPVEIAWGTHESKLPPLAHIPPYGPKNVILLPQMGVNAWVRSWIPDEEIVGMAIRHGESYGLSKLLTVWEGEKAVYR
PTVHYAYMPSHDTLSSLCELRGRNYELQPRLRIMTNEIVSGEDIMGALLMGHSYNSWWTGSALSIEEARSLAPGQNATTL
QVAAGIVAAILWMLENPREGVKTPEDLPHDFVLDIARPYLGKFISTPSDWTPLKNRKIFFKESPAVKHDPDPWQFENFIF
VG

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 54660; Mature: 54660

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRFSNKVLIIGYGSVSQCTLPLLLDKLDIPLENITLIDFEDKSKALKKYTNQGLTFVR
CCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCHHHHH
EKITPENLDQVLSQNMENEGMIIDLSWNIDANEIVKWCHDHDVLYVNTSVEVWDPAEKFL
HHCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCEEECCHHHHHH
TQSLLEKSLYLRQMRLQELSRDWKDAPTAVVDHGANPGLITHFVKQGLLDIAARTCEDKK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VSPEDEQEIALLAKNRDFARLARKLGIRVIHCSERDTQIASRPKEVNEFVGTWSIEGLRE
CCCCCCCCEEEEECCCCHHHHHHHHCEEEEEECCCCCHHHCCCHHHHHHHCCCEECCHHH
EGTAPVEIAWGTHESKLPPLAHIPPYGPKNVILLPQMGVNAWVRSWIPDEEIVGMAIRHG
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHCC
ESYGLSKLLTVWEGEKAVYRPTVHYAYMPSHDTLSSLCELRGRNYELQPRLRIMTNEIVS
CCCCHHHHHHHHCCCCEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHEEHHHHHCC
GEDIMGALLMGHSYNSWWTGSALSIEEARSLAPGQNATTLQVAAGIVAAILWMLENPREG
CHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHC
VKTPEDLPHDFVLDIARPYLGKFISTPSDWTPLKNRKIFFKESPAVKHDPDPWQFENFIF
CCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEE
VG
EC
>Mature Secondary Structure
MKKRFSNKVLIIGYGSVSQCTLPLLLDKLDIPLENITLIDFEDKSKALKKYTNQGLTFVR
CCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCHHHHH
EKITPENLDQVLSQNMENEGMIIDLSWNIDANEIVKWCHDHDVLYVNTSVEVWDPAEKFL
HHCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCEEECCHHHHHH
TQSLLEKSLYLRQMRLQELSRDWKDAPTAVVDHGANPGLITHFVKQGLLDIAARTCEDKK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VSPEDEQEIALLAKNRDFARLARKLGIRVIHCSERDTQIASRPKEVNEFVGTWSIEGLRE
CCCCCCCCEEEEECCCCHHHHHHHHCEEEEEECCCCCHHHCCCHHHHHHHCCCEECCHHH
EGTAPVEIAWGTHESKLPPLAHIPPYGPKNVILLPQMGVNAWVRSWIPDEEIVGMAIRHG
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHCC
ESYGLSKLLTVWEGEKAVYRPTVHYAYMPSHDTLSSLCELRGRNYELQPRLRIMTNEIVS
CCCCHHHHHHHHCCCCEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHEEHHHHHCC
GEDIMGALLMGHSYNSWWTGSALSIEEARSLAPGQNATTLQVAAGIVAAILWMLENPREG
CHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHC
VKTPEDLPHDFVLDIARPYLGKFISTPSDWTPLKNRKIFFKESPAVKHDPDPWQFENFIF
CCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEE
VG
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]