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The map label for this gene is TrkA [H]

Identifier: 20094447

GI number: 20094447

Start: 971489

End: 972157

Strand: Direct

Name: TrkA [H]

Synonym: MK1011

Alternate gene names: 20094447

Gene position: 971489-972157 (Clockwise)

Preceding gene: 20094446

Following gene: 20094448

Centisome position: 57.32

GC content: 59.49

Gene sequence:

>669_bases
ATGTACGTGGTGGTCGTGGGGGGCGGACGCGTCGGTAGGATACTGGCCGAGTTGCTGATAGCTCACGGTCACGACGTCGT
CGTGATAGAAAAGGATAAAAGGAGAGCCAGGGAGCTCGCGCAGTCCGAACTGGACGTCCTGGTCGTCCAGGGAGACGCCA
CCGACCTCGACGTGTTGCAGGACGCCGAGATCGAGACAGCGGACGTCGTCGCGGCCGTGACCGATAAGGATGAGGTTAAC
CTCGCCGTGTCCCTGATAGCCAAGGAGGAATTCGGTGTCGAGCGGGTCGTATCCCGCGTGACTGATGACCGGTTCGTGGA
CGTATTCCGACGCCTAGGGGTGGATGCAGTCGTAAACCCCGATCGCAGTGCCGCGCAACTCATAGAGAAGGCGATCACGA
GGCATAATCTCGTGGATGTGATTATGTTCGGGCGCGGCGAGGCCGAGCTCTTGGAGTTCGAGGTGACCGAAGACTCTCTG
GTATCCGGGAAGAAAATCTCGGAGATCCCGGCCGACTGCGTGATAGTGGCCATATATCGGGATGACGAGCTGGAGCTACC
CCGCGGCGACATGGAAATAAACCCGGGTGATCGGGTCCTCGTGCTCGCGCTACGTGACAAGCTCAAGAAGGTCGAGAAAC
TCTTCAAAGGCCGCGACGAAGGGGAGTGA

Upstream 100 bases:

>100_bases
CCTCTACTGGCTGACCTTGATCCTGAAGAGGCTCGCCGTCAAAGGTAGGGACTGATCCCCTCGCCCTCCAGGGTGGGGTT
CTCCGGGGGTCGTGAGGGGC

Downstream 100 bases:

>100_bases
CCCACATGGCGTCCGTTGCTCAGGTTCTAGACCGTATCCGATCCGCCGAAACCGAGGCGCAGCGCAAGGTCGAGGAGGCT
CGTGAGAAGGCCGAGAAGAT

Product: NAD-binding component of a K+ transport system

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MYVVVVGGGRVGRILAELLIAHGHDVVVIEKDKRRARELAQSELDVLVVQGDATDLDVLQDAEIETADVVAAVTDKDEVN
LAVSLIAKEEFGVERVVSRVTDDRFVDVFRRLGVDAVVNPDRSAAQLIEKAITRHNLVDVIMFGRGEAELLEFEVTEDSL
VSGKKISEIPADCVIVAIYRDDELELPRGDMEINPGDRVLVLALRDKLKKVEKLFKGRDEGE

Sequences:

>Translated_222_residues
MYVVVVGGGRVGRILAELLIAHGHDVVVIEKDKRRARELAQSELDVLVVQGDATDLDVLQDAEIETADVVAAVTDKDEVN
LAVSLIAKEEFGVERVVSRVTDDRFVDVFRRLGVDAVVNPDRSAAQLIEKAITRHNLVDVIMFGRGEAELLEFEVTEDSL
VSGKKISEIPADCVIVAIYRDDELELPRGDMEINPGDRVLVLALRDKLKKVEKLFKGRDEGE
>Mature_222_residues
MYVVVVGGGRVGRILAELLIAHGHDVVVIEKDKRRARELAQSELDVLVVQGDATDLDVLQDAEIETADVVAAVTDKDEVN
LAVSLIAKEEFGVERVVSRVTDDRFVDVFRRLGVDAVVNPDRSAAQLIEKAITRHNLVDVIMFGRGEAELLEFEVTEDSL
VSGKKISEIPADCVIVAIYRDDELELPRGDMEINPGDRVLVLALRDKLKKVEKLFKGRDEGE

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=221, Percent_Identity=30.316742081448, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 24540; Mature: 24540

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVVVVGGGRVGRILAELLIAHGHDVVVIEKDKRRARELAQSELDVLVVQGDATDLDVLQ
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCCCCHHHC
DAEIETADVVAAVTDKDEVNLAVSLIAKEEFGVERVVSRVTDDRFVDVFRRLGVDAVVNP
CCCCCHHHEEEEECCCCCCEEEEEEEEHHHCCHHHHHHHHCCHHHHHHHHHCCCCEEECC
DRSAAQLIEKAITRHNLVDVIMFGRGEAELLEFEVTEDSLVSGKKISEIPADCVIVAIYR
CHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCHHCCCCHHHCCCCCEEEEEEEE
DDELELPRGDMEINPGDRVLVLALRDKLKKVEKLFKGRDEGE
CCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYVVVVGGGRVGRILAELLIAHGHDVVVIEKDKRRARELAQSELDVLVVQGDATDLDVLQ
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCCCCHHHC
DAEIETADVVAAVTDKDEVNLAVSLIAKEEFGVERVVSRVTDDRFVDVFRRLGVDAVVNP
CCCCCHHHEEEEECCCCCCEEEEEEEEHHHCCHHHHHHHHCCHHHHHHHHHCCCCEEECC
DRSAAQLIEKAITRHNLVDVIMFGRGEAELLEFEVTEDSLVSGKKISEIPADCVIVAIYR
CHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCHHCCCCHHHCCCCCEEEEEEEE
DDELELPRGDMEINPGDRVLVLALRDKLKKVEKLFKGRDEGE
CCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]