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The map label for this gene is NtpI [H]

Identifier: 20094448

GI number: 20094448

Start: 972487

End: 974457

Strand: Direct

Name: NtpI [H]

Synonym: MK1012

Alternate gene names: 20094448

Gene position: 972487-974457 (Clockwise)

Preceding gene: 20094447

Following gene: 20094449

Centisome position: 57.37

GC content: 58.6

Gene sequence:

>1971_bases
GTGGCCATCGAGCCGATGCGTGAGGTCTTCGTGTTCTGCCTGGACGAGAAGGTGTCGGACCTACTCAAGCGGGTTCAGCT
CGAGGGTTGCCTCCACGTCGAGGATTTCTGGGAGGCTCACGGCGTCGAGAAGTTCTACGGTGTGAAACGCCCGGAGGTAC
CTCAGGAACTGATGAAGCTCACCGACGTACTCACACGGCTTGCGAGGATCGAGGAATCGCTCCGTCGCATCCACGAGGAA
GTCCGGTCCACCGGGCTACTCGATGCACTGAAACCCATGTTCAAGGCGGAGCGGCCTGAAACCGTGGAGTTCGAGCTCAA
GCCGACCGAAGAGATCGTAGAGGACGCGAACGAGTTCCTCGAGGAGCTGGAGTCCGAGGCCGGGGAGAAACTGAAGCGAC
TGAACGAGCTCAAGGACGAGCTCGAGCGACTCGAGGAGGCGTGTTCCTTCCTGGAATACGTGGAAGAGGACTTCAACGTC
TCCCACCTGGGTGAAGGACCGCGCGTGGTCGCTCGACTCTACACCGTGCGGGCCGACTCCTGGGACGATCTAGTCCAGGA
GCTCGACGGCGAACCCGCGTACGTGGGGAAGGTAGGGGAGACCGAAGACGGCGATCCCATAGCCGTGATAGCGTTCCCGA
AGGGTAGCGGAATAGAGTCCGAAATCCGCAGGCTCGGAGCCATGGAAGAGGAGGTAGTGAACGAGGTCCTCGAGGATCGT
GAAGGTTCCGTTCAGTCGGTCCGCGAGGAGTTGGCTGAGGAGATAGAGGAAGTCAAGGACGAGCTCGAGCGAACGAAGCA
TGAACTCGCGGAATTCTACGAGGAGCGTGGTACGGAGATCCGAGCGTGGGTGGAGCTTCTGGAGAACGAGCGCGAGCTGT
TCGACGTGTTACCCAAGCTCGCCATGACCGATAGGACCTACCTGATCTATGGCTGGGTGCCGGAGGAGGAAGTCGGCAGG
TTCAAGGAGGTCGTGAAGGAGGCTACCGATGGACTATGCGAGATAGTAGTGCACGAGCCGTCGGACCTCGAGAACATGCC
CGTACGCCTACGTAACCCGAGGTTCATCCAGCCTTTCGAAACCCTCGTGGAGATGTTCTCCCTGCCGAAGCCCACGGAGA
TCGATCCTACACCGATAGTGGCGATATTCTTCCCGATATACTTCGGTTTCATCCTGACAGATGCCGCCTACGGGGCCATC
CTCACAGCATTGGCAGCAGCGATCCGTATGGGAGCGGGGCGGGTCGATGAGAGCATCCGGAAATTCTCCGAGATACTGCT
GTACGCGGGTATCGTTACGATCATCCTCGGTGCACTCACCGGCGGTTACTTCGGGAACCTGTTGGGGATCAAACCGCTGT
GGGTAGACCCGATGAAGGACCCGATCACGATACTCATCGTGGCGCTGGGCTTCGGAGTTCTACATGTCGGTATCGGATTG
ATGCTCGGAATGTACGTCTCCCTCAGAAAGCAGCGTGACATGAGGTCCTTCATGCTCGACTACCTGTGCTGGTTCCTGAT
CCTCCTCGGCGGTCTGCTACTGGCGGTGGCGTACAAGACGGGCGGAATCTACACACCACTCGGATACGCCGGAATCGCCA
TCGCGGGGCTGGGCTTCGTCCTCGTACTGGCCGGTCACAAGCTCCTGGGTGTCCTGGACACCATCGGGTTCATGGGTGAC
ATACTATCCTACTCACGACTGCTAGCCGGATGTCTGTCAACCGCCGGTATCGCGCTGGTGGTCAACCTGCTGGCTAAAAT
GGTCGAGGGACTCGGTGTAGTGGGGTACGTGATCGCGGGGATCATCCTCATCGGTGGACACTTGTTCAACATGGCAATGA
ACGGACTTGGAGCCTTCGTGCACAGCCTACGATTGCACTACGTGGAGTTCTTCAGCAAGTTCTACGAAGGAGGCGGAAAG
CCGTTCGAACCGCTAGAGCTCAAGGGTGAGCACGTAGAAATACGCGCTTGA

Upstream 100 bases:

>100_bases
GGAGGGTGAGCGGGAGATCGAGGAGCTCCGAAGTCAGGCTGAGGAGAGACTGGATGAAGCCGCCGATGCCGTCGTCGGGC
TAGTTCTGGGGGAGTGAATA

Downstream 100 bases:

>100_bases
GGGGGGAAATCCGGATGGTGAGTACCGAACTCACGATCGCCGCCATCGGAGCGGGTCTGGCGGCCGGCGTCGCGGGTGTG
GGTTCCGGTATTGGTCAGGG

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I [H]

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MAIEPMREVFVFCLDEKVSDLLKRVQLEGCLHVEDFWEAHGVEKFYGVKRPEVPQELMKLTDVLTRLARIEESLRRIHEE
VRSTGLLDALKPMFKAERPETVEFELKPTEEIVEDANEFLEELESEAGEKLKRLNELKDELERLEEACSFLEYVEEDFNV
SHLGEGPRVVARLYTVRADSWDDLVQELDGEPAYVGKVGETEDGDPIAVIAFPKGSGIESEIRRLGAMEEEVVNEVLEDR
EGSVQSVREELAEEIEEVKDELERTKHELAEFYEERGTEIRAWVELLENERELFDVLPKLAMTDRTYLIYGWVPEEEVGR
FKEVVKEATDGLCEIVVHEPSDLENMPVRLRNPRFIQPFETLVEMFSLPKPTEIDPTPIVAIFFPIYFGFILTDAAYGAI
LTALAAAIRMGAGRVDESIRKFSEILLYAGIVTIILGALTGGYFGNLLGIKPLWVDPMKDPITILIVALGFGVLHVGIGL
MLGMYVSLRKQRDMRSFMLDYLCWFLILLGGLLLAVAYKTGGIYTPLGYAGIAIAGLGFVLVLAGHKLLGVLDTIGFMGD
ILSYSRLLAGCLSTAGIALVVNLLAKMVEGLGVVGYVIAGIILIGGHLFNMAMNGLGAFVHSLRLHYVEFFSKFYEGGGK
PFEPLELKGEHVEIRA

Sequences:

>Translated_656_residues
MAIEPMREVFVFCLDEKVSDLLKRVQLEGCLHVEDFWEAHGVEKFYGVKRPEVPQELMKLTDVLTRLARIEESLRRIHEE
VRSTGLLDALKPMFKAERPETVEFELKPTEEIVEDANEFLEELESEAGEKLKRLNELKDELERLEEACSFLEYVEEDFNV
SHLGEGPRVVARLYTVRADSWDDLVQELDGEPAYVGKVGETEDGDPIAVIAFPKGSGIESEIRRLGAMEEEVVNEVLEDR
EGSVQSVREELAEEIEEVKDELERTKHELAEFYEERGTEIRAWVELLENERELFDVLPKLAMTDRTYLIYGWVPEEEVGR
FKEVVKEATDGLCEIVVHEPSDLENMPVRLRNPRFIQPFETLVEMFSLPKPTEIDPTPIVAIFFPIYFGFILTDAAYGAI
LTALAAAIRMGAGRVDESIRKFSEILLYAGIVTIILGALTGGYFGNLLGIKPLWVDPMKDPITILIVALGFGVLHVGIGL
MLGMYVSLRKQRDMRSFMLDYLCWFLILLGGLLLAVAYKTGGIYTPLGYAGIAIAGLGFVLVLAGHKLLGVLDTIGFMGD
ILSYSRLLAGCLSTAGIALVVNLLAKMVEGLGVVGYVIAGIILIGGHLFNMAMNGLGAFVHSLRLHYVEFFSKFYEGGGK
PFEPLELKGEHVEIRA
>Mature_655_residues
AIEPMREVFVFCLDEKVSDLLKRVQLEGCLHVEDFWEAHGVEKFYGVKRPEVPQELMKLTDVLTRLARIEESLRRIHEEV
RSTGLLDALKPMFKAERPETVEFELKPTEEIVEDANEFLEELESEAGEKLKRLNELKDELERLEEACSFLEYVEEDFNVS
HLGEGPRVVARLYTVRADSWDDLVQELDGEPAYVGKVGETEDGDPIAVIAFPKGSGIESEIRRLGAMEEEVVNEVLEDRE
GSVQSVREELAEEIEEVKDELERTKHELAEFYEERGTEIRAWVELLENERELFDVLPKLAMTDRTYLIYGWVPEEEVGRF
KEVVKEATDGLCEIVVHEPSDLENMPVRLRNPRFIQPFETLVEMFSLPKPTEIDPTPIVAIFFPIYFGFILTDAAYGAIL
TALAAAIRMGAGRVDESIRKFSEILLYAGIVTIILGALTGGYFGNLLGIKPLWVDPMKDPITILIVALGFGVLHVGIGLM
LGMYVSLRKQRDMRSFMLDYLCWFLILLGGLLLAVAYKTGGIYTPLGYAGIAIAGLGFVLVLAGHKLLGVLDTIGFMGDI
LSYSRLLAGCLSTAGIALVVNLLAKMVEGLGVVGYVIAGIILIGGHLFNMAMNGLGAFVHSLRLHYVEFFSKFYEGGGKP
FEPLELKGEHVEIRA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 73476; Mature: 73345

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEPMREVFVFCLDEKVSDLLKRVQLEGCLHVEDFWEAHGVEKFYGVKRPEVPQELMKL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHCCCCCCCHHHHHHH
TDVLTRLARIEESLRRIHEEVRSTGLLDALKPMFKAERPETVEFELKPTEEIVEDANEFL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHH
EELESEAGEKLKRLNELKDELERLEEACSFLEYVEEDFNVSHLGEGPRVVARLYTVRADS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCC
WDDLVQELDGEPAYVGKVGETEDGDPIAVIAFPKGSGIESEIRRLGAMEEEVVNEVLEDR
HHHHHHHCCCCCCEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHCC
EGSVQSVREELAEEIEEVKDELERTKHELAEFYEERGTEIRAWVELLENERELFDVLPKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AMTDRTYLIYGWVPEEEVGRFKEVVKEATDGLCEIVVHEPSDLENMPVRLRNPRFIQPFE
HHCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCEECCCCCCCHHH
TLVEMFSLPKPTEIDPTPIVAIFFPIYFGFILTDAAYGAILTALAAAIRMGAGRVDESIR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KFSEILLYAGIVTIILGALTGGYFGNLLGIKPLWVDPMKDPITILIVALGFGVLHVGIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MLGMYVSLRKQRDMRSFMLDYLCWFLILLGGLLLAVAYKTGGIYTPLGYAGIAIAGLGFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LVLAGHKLLGVLDTIGFMGDILSYSRLLAGCLSTAGIALVVNLLAKMVEGLGVVGYVIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IILIGGHLFNMAMNGLGAFVHSLRLHYVEFFSKFYEGGGKPFEPLELKGEHVEIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
AIEPMREVFVFCLDEKVSDLLKRVQLEGCLHVEDFWEAHGVEKFYGVKRPEVPQELMKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHCCCCCCCHHHHHHH
TDVLTRLARIEESLRRIHEEVRSTGLLDALKPMFKAERPETVEFELKPTEEIVEDANEFL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHH
EELESEAGEKLKRLNELKDELERLEEACSFLEYVEEDFNVSHLGEGPRVVARLYTVRADS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCC
WDDLVQELDGEPAYVGKVGETEDGDPIAVIAFPKGSGIESEIRRLGAMEEEVVNEVLEDR
HHHHHHHCCCCCCEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHCC
EGSVQSVREELAEEIEEVKDELERTKHELAEFYEERGTEIRAWVELLENERELFDVLPKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AMTDRTYLIYGWVPEEEVGRFKEVVKEATDGLCEIVVHEPSDLENMPVRLRNPRFIQPFE
HHCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCEECCCCCCCHHH
TLVEMFSLPKPTEIDPTPIVAIFFPIYFGFILTDAAYGAILTALAAAIRMGAGRVDESIR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KFSEILLYAGIVTIILGALTGGYFGNLLGIKPLWVDPMKDPITILIVALGFGVLHVGIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MLGMYVSLRKQRDMRSFMLDYLCWFLILLGGLLLAVAYKTGGIYTPLGYAGIAIAGLGFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LVLAGHKLLGVLDTIGFMGDILSYSRLLAGCLSTAGIALVVNLLAKMVEGLGVVGYVIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IILIGGHLFNMAMNGLGAFVHSLRLHYVEFFSKFYEGGGKPFEPLELKGEHVEIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]