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The map label for this gene is TrkG [C]

Identifier: 20094446

GI number: 20094446

Start: 969971

End: 971443

Strand: Direct

Name: TrkG [C]

Synonym: MK1010

Alternate gene names: 20094446

Gene position: 969971-971443 (Clockwise)

Preceding gene: 20094445

Following gene: 20094447

Centisome position: 57.23

GC content: 60.76

Gene sequence:

>1473_bases
GTGGACGTGAAGCTGGTGAGCAGTATCCTAGGAACCGTCGTGAAGGTCGCCGCCGTGCTCCCGCTACTCCCCCTCCCGAT
TTCGCTACTTTACGGGGAATTAGACTGCATCGCTCCTCTCCTCTTGACTTCCCTCATCATGCTCGTCTGCGGGGTCGCCC
TCGAGCGGATCGCGAGGGTTGAGCGCCACGTTCGTCCGAGACATGCGATAGTTGCCGTGCCCATAATTTGGCTCGTGATC
CCACTCTTCACGTCGCTTCCTTACCGTTTTTGCGAACACATGTCGTGGCTGGACGCTTACTTCGAAAGCATGTCTGGATG
GACTACGACAGGTCTCACCGTGCTCCCGGACATCGACCACGCGCACCGCACCATCCTGTTCTGGAGAAGCCTCGAGCAGT
GGGTAGGAGGCCTGGGTATCGTCGTGTCGATTATCAGCATCCTCAGGTTCGAAACACCGAGCCTTCTGTACGTCGCCGAG
GCCCGCGAGGAACGGATCAGACCGAACGTCGTTAACACAGCGAAAGAGATGTGGAAGATCTACATCACGATCACCGCGGT
GGGTTTCCTAGCCCTGTGGGCCGCGGGGATGAATCCCTTCGACGCGCTGAACCACTCCATGACCGCGGTTGCCACCGGAG
GGTTCTCCACGCGGTCCGAGAGCGTCACCGCGTGGCACTCACCGACCGTTGAACTCATCACGGTCGTCCTCATGGTGCTC
GGTGCCACCAGCTTCGTCACTCACTACAGGGTGGCCAAGACCTTCCGTACGTCTCCCGCCGAACTTCCGAAGCGGATCAT
CAAGGCACTTCGACAGTACCTCCAAGATCGTCAGTTCCTCACCATGATCGGTCTCACCGCCGCCGTCACCGCGTATGCGG
GCGCGGTATCCGGCGACCGAGCGTGGGACGTCGTCCGGTACTACGGGTACCAGGCGGTGTCCGCCATCACCTGCTGTGGA
TTCTCCAACGCGGACGTTCTCTCCTTCCCCGAGTACGCCAAGCTGGCTATAACCATCCTCATGATAGTCGGAGGATCCAC
GGCCTCTACGGCGGGAGCCATTAAGGTCTTGCGTTTCCTGATCATGGCGGAGGCCGTGAAGGCGGCCATCGCACGTAGGA
CTCAACCTATCCGAGGCGTGGTCGTCCCTCGCATCGGCAGTAGGGTACTCTCCGAGGATGAGATCTCCGACGCGTTCGCG
ATCGCCTCGGCGTACATGTTCTTCCTGCTCATAGGCACGCTGCTGCTCACGGCGTACGGATACCCGCTGGTCGACGCCCT
GTTCGAGGTCGCGTCGGCACAGGGCGGCGTCGGGCTGTCCTCGGGGATCACGGCGCCCAACGCGCCGGCGTTCGTGAAAA
TCCTGCTTATCTTCCACATGTGGATAGGCAGGCTGGAGGTTCTGCCGTGCCTAGCGGCCCTCTACTGGCTGACCTTGATC
CTGAAGAGGCTCGCCGTCAAAGGTAGGGACTGA

Upstream 100 bases:

>100_bases
GGAGCGTTTTACGGTGTCGTCATCACCAGACCGGTGTACGCAGACCTGCTGAAGAAGATACTCGGAACGGAGTAGGGGGG
AGGTAGAAACGGACCCGATC

Downstream 100 bases:

>100_bases
TCCCCTCGCCCTCCAGGGTGGGGTTCTCCGGGGGTCGTGAGGGGCATGTACGTGGTGGTCGTGGGGGGCGGACGCGTCGG
TAGGATACTGGCCGAGTTGC

Product: potassium transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MDVKLVSSILGTVVKVAAVLPLLPLPISLLYGELDCIAPLLLTSLIMLVCGVALERIARVERHVRPRHAIVAVPIIWLVI
PLFTSLPYRFCEHMSWLDAYFESMSGWTTTGLTVLPDIDHAHRTILFWRSLEQWVGGLGIVVSIISILRFETPSLLYVAE
AREERIRPNVVNTAKEMWKIYITITAVGFLALWAAGMNPFDALNHSMTAVATGGFSTRSESVTAWHSPTVELITVVLMVL
GATSFVTHYRVAKTFRTSPAELPKRIIKALRQYLQDRQFLTMIGLTAAVTAYAGAVSGDRAWDVVRYYGYQAVSAITCCG
FSNADVLSFPEYAKLAITILMIVGGSTASTAGAIKVLRFLIMAEAVKAAIARRTQPIRGVVVPRIGSRVLSEDEISDAFA
IASAYMFFLLIGTLLLTAYGYPLVDALFEVASAQGGVGLSSGITAPNAPAFVKILLIFHMWIGRLEVLPCLAALYWLTLI
LKRLAVKGRD

Sequences:

>Translated_490_residues
MDVKLVSSILGTVVKVAAVLPLLPLPISLLYGELDCIAPLLLTSLIMLVCGVALERIARVERHVRPRHAIVAVPIIWLVI
PLFTSLPYRFCEHMSWLDAYFESMSGWTTTGLTVLPDIDHAHRTILFWRSLEQWVGGLGIVVSIISILRFETPSLLYVAE
AREERIRPNVVNTAKEMWKIYITITAVGFLALWAAGMNPFDALNHSMTAVATGGFSTRSESVTAWHSPTVELITVVLMVL
GATSFVTHYRVAKTFRTSPAELPKRIIKALRQYLQDRQFLTMIGLTAAVTAYAGAVSGDRAWDVVRYYGYQAVSAITCCG
FSNADVLSFPEYAKLAITILMIVGGSTASTAGAIKVLRFLIMAEAVKAAIARRTQPIRGVVVPRIGSRVLSEDEISDAFA
IASAYMFFLLIGTLLLTAYGYPLVDALFEVASAQGGVGLSSGITAPNAPAFVKILLIFHMWIGRLEVLPCLAALYWLTLI
LKRLAVKGRD
>Mature_490_residues
MDVKLVSSILGTVVKVAAVLPLLPLPISLLYGELDCIAPLLLTSLIMLVCGVALERIARVERHVRPRHAIVAVPIIWLVI
PLFTSLPYRFCEHMSWLDAYFESMSGWTTTGLTVLPDIDHAHRTILFWRSLEQWVGGLGIVVSIISILRFETPSLLYVAE
AREERIRPNVVNTAKEMWKIYITITAVGFLALWAAGMNPFDALNHSMTAVATGGFSTRSESVTAWHSPTVELITVVLMVL
GATSFVTHYRVAKTFRTSPAELPKRIIKALRQYLQDRQFLTMIGLTAAVTAYAGAVSGDRAWDVVRYYGYQAVSAITCCG
FSNADVLSFPEYAKLAITILMIVGGSTASTAGAIKVLRFLIMAEAVKAAIARRTQPIRGVVVPRIGSRVLSEDEISDAFA
IASAYMFFLLIGTLLLTAYGYPLVDALFEVASAQGGVGLSSGITAPNAPAFVKILLIFHMWIGRLEVLPCLAALYWLTLI
LKRLAVKGRD

Specific function: Low-Affinity Potassium Transport System. Interacts With Trk System Potassium Uptake Protein Trka. Trke Increases The Affinity Of The System. [C]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=500, Percent_Identity=25.8, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI48994987, Length=492, Percent_Identity=28.6585365853659, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53632; Mature: 53632

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKLVSSILGTVVKVAAVLPLLPLPISLLYGELDCIAPLLLTSLIMLVCGVALERIARV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERHVRPRHAIVAVPIIWLVIPLFTSLPYRFCEHMSWLDAYFESMSGWTTTGLTVLPDIDH
HHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCH
AHRTILFWRSLEQWVGGLGIVVSIISILRFETPSLLYVAEAREERIRPNVVNTAKEMWKI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHH
YITITAVGFLALWAAGMNPFDALNHSMTAVATGGFSTRSESVTAWHSPTVELITVVLMVL
HHHHHHHHHHHHHHCCCCHHHHHCCCHHHEEECCCCCCCCCEEECCCCHHHHHHHHHHHH
GATSFVTHYRVAKTFRTSPAELPKRIIKALRQYLQDRQFLTMIGLTAAVTAYAGAVSGDR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCH
AWDVVRYYGYQAVSAITCCGFSNADVLSFPEYAKLAITILMIVGGSTASTAGAIKVLRFL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IMAEAVKAAIARRTQPIRGVVVPRIGSRVLSEDEISDAFAIASAYMFFLLIGTLLLTAYG
HHHHHHHHHHHHCCCCCCCEECCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPLVDALFEVASAQGGVGLSSGITAPNAPAFVKILLIFHMWIGRLEVLPCLAALYWLTLI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRLAVKGRD
HHHHHCCCCC
>Mature Secondary Structure
MDVKLVSSILGTVVKVAAVLPLLPLPISLLYGELDCIAPLLLTSLIMLVCGVALERIARV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERHVRPRHAIVAVPIIWLVIPLFTSLPYRFCEHMSWLDAYFESMSGWTTTGLTVLPDIDH
HHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCH
AHRTILFWRSLEQWVGGLGIVVSIISILRFETPSLLYVAEAREERIRPNVVNTAKEMWKI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHH
YITITAVGFLALWAAGMNPFDALNHSMTAVATGGFSTRSESVTAWHSPTVELITVVLMVL
HHHHHHHHHHHHHHCCCCHHHHHCCCHHHEEECCCCCCCCCEEECCCCHHHHHHHHHHHH
GATSFVTHYRVAKTFRTSPAELPKRIIKALRQYLQDRQFLTMIGLTAAVTAYAGAVSGDR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCH
AWDVVRYYGYQAVSAITCCGFSNADVLSFPEYAKLAITILMIVGGSTASTAGAIKVLRFL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IMAEAVKAAIARRTQPIRGVVVPRIGSRVLSEDEISDAFAIASAYMFFLLIGTLLLTAYG
HHHHHHHHHHHHCCCCCCCEECCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPLVDALFEVASAQGGVGLSSGITAPNAPAFVKILLIFHMWIGRLEVLPCLAALYWLTLI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRLAVKGRD
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]