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The map label for this gene is CdhC

Identifier: 20094157

GI number: 20094157

Start: 687632

End: 689035

Strand: Direct

Name: CdhC

Synonym: MK0720

Alternate gene names: 20094157

Gene position: 687632-689035 (Clockwise)

Preceding gene: 20094156

Following gene: 20094158

Centisome position: 40.57

GC content: 59.97

Gene sequence:

>1404_bases
TTGACGAGTCTTGCGGATCTACCCGTGGACGTGAGCCCGAGGCACGAGGGCGAGCGGATACGAAGCGGCGACATGTACGT
CGAGCTAGCGGGCCCAAAGAGCTTCGGTGCCGAACTGTTCAAGGTGGTGGATCCGGACGAGATCGAGCCGGACAAAGTGG
AAGTCATCGGCCCGGATATCGATGAGATGGAGGAGGGAGGGAGATACCCGTTCGCCATCTACGTGAAGGCGGCGGGCGAG
GAACTCGAGGAGGACGTGGAAGGTGTGCTAGAGCGACGTATCCACGAGTTCTGCAACTACGTCGAGGGTTTCATGCACCT
GAACCAGCGAGATCAGATCTGGTGTAGGGTCTCCAAGAACGTCACGGAGAAGGGCTTCCGGCTGGAACACCTCGGCATCG
CGCTCCGAGAGCTGTACAAGGAGGAGTTCGGCAACGTCATCGACTCCGTGGAAGTCACGATAATGACGGACGAGGAGAAA
GTGGAGGAGTTTTTGGAGTACGCCAGGAGAGTCTACAAAAAGCGTGATGAGCGTGCGAAGGGACTCTCGGAGGAGGACGT
CAACGAGTTCTACGTGTGCCTGATGTGCCAGTCCTTCGCGCCCACTCACGTGTGCGTAATCACACCGGACCGGCCGAGCC
TCTGTGGATCGATCACCTGGCACGACGCCAAGGCGGCCTACAAGATCGATCCAGAAGGCCCCATATTCCCGATCGAGAAG
GGAGAGTGCCTCGATCCCGAGGCCGGCGAGTACGAGGGTGTGAACGAGGCGGTCAAAGAACACTCACAGGGCACTGTGGA
GCGGGTTTACCTGCACTCCTGTCTCGAGTACCCGCATACGAGCTGCGGCTGCTTCCAGGCCGTCGTGTTCTACATCCCCG
AGGTAGACGGATTCGGAATCGTCGACCGCGAGTACCCGGGTGAGACCCCGATCGGGCTCCCGTTCTCGACCATGGCGGGT
GAAGCCAGTGGCGGTGAGCAGCAGCCGGGCTTCGTCGGCGTAAGCTACGGTTACATGGAGTCCGATAAGTTCCTACAGTA
CGACGGCGGCTGGGAGCGCGTGGTTTGGATGCCTAAGGCGCTGAAAGAACGCATGAAGCACGCCATCCCCGACGAGCTGT
ACGACAAGATAGCCACCGAGGAGGATGCGACCACCGTGGAAGAGCTCCGGGAGTTCCTCGAGAAAGTCGAGCACCCGGTC
GTCGAGCGCTGGGCCGAAGAGGAGGAAGAAGAGGAGGAGAAGGCTCCGGAAGAGGAAGCGCCGGCCGAAGAGCCGACGAT
GGAGGTGAAGGAGCTCCCGATCGCGCCCGGTGGTGGTCTGAACGTGAAAATCGTGCTGAAAAACGCGAAGATCTACGCTG
AGAAGGTCATCATCAAGCGCGCCGACCGGGAAGATAAGAGTTGA

Upstream 100 bases:

>100_bases
CGCTCAGGTCCGAGATACGGGAGCTGCTGGAGGAGACCGGGTGGACACCTAGATCGCGCGCATCCGATCCTACCCTACTA
CCCGAGGGGTGAATGTAACA

Downstream 100 bases:

>100_bases
TCATAGCCTTCACTGGGAAGGGAGGCACGGGGAAGACTCTCCTCGCCGCACTCACAGTACTCGAGCTCCTCGACCGACAC
CCCGACGCCGACCTGCTGGT

Product: acetyl-CoA decarbonylase/synthase complex subunit beta

Products: CO2; AH2

Alternate protein names: ACDS complex subunit beta; ACDS complex acyltransferase

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTSLADLPVDVSPRHEGERIRSGDMYVELAGPKSFGAELFKVVDPDEIEPDKVEVIGPDIDEMEEGGRYPFAIYVKAAGE
ELEEDVEGVLERRIHEFCNYVEGFMHLNQRDQIWCRVSKNVTEKGFRLEHLGIALRELYKEEFGNVIDSVEVTIMTDEEK
VEEFLEYARRVYKKRDERAKGLSEEDVNEFYVCLMCQSFAPTHVCVITPDRPSLCGSITWHDAKAAYKIDPEGPIFPIEK
GECLDPEAGEYEGVNEAVKEHSQGTVERVYLHSCLEYPHTSCGCFQAVVFYIPEVDGFGIVDREYPGETPIGLPFSTMAG
EASGGEQQPGFVGVSYGYMESDKFLQYDGGWERVVWMPKALKERMKHAIPDELYDKIATEEDATTVEELREFLEKVEHPV
VERWAEEEEEEEEKAPEEEAPAEEPTMEVKELPIAPGGGLNVKIVLKNAKIYAEKVIIKRADREDKS

Sequences:

>Translated_467_residues
MTSLADLPVDVSPRHEGERIRSGDMYVELAGPKSFGAELFKVVDPDEIEPDKVEVIGPDIDEMEEGGRYPFAIYVKAAGE
ELEEDVEGVLERRIHEFCNYVEGFMHLNQRDQIWCRVSKNVTEKGFRLEHLGIALRELYKEEFGNVIDSVEVTIMTDEEK
VEEFLEYARRVYKKRDERAKGLSEEDVNEFYVCLMCQSFAPTHVCVITPDRPSLCGSITWHDAKAAYKIDPEGPIFPIEK
GECLDPEAGEYEGVNEAVKEHSQGTVERVYLHSCLEYPHTSCGCFQAVVFYIPEVDGFGIVDREYPGETPIGLPFSTMAG
EASGGEQQPGFVGVSYGYMESDKFLQYDGGWERVVWMPKALKERMKHAIPDELYDKIATEEDATTVEELREFLEKVEHPV
VERWAEEEEEEEEKAPEEEAPAEEPTMEVKELPIAPGGGLNVKIVLKNAKIYAEKVIIKRADREDKS
>Mature_466_residues
TSLADLPVDVSPRHEGERIRSGDMYVELAGPKSFGAELFKVVDPDEIEPDKVEVIGPDIDEMEEGGRYPFAIYVKAAGEE
LEEDVEGVLERRIHEFCNYVEGFMHLNQRDQIWCRVSKNVTEKGFRLEHLGIALRELYKEEFGNVIDSVEVTIMTDEEKV
EEFLEYARRVYKKRDERAKGLSEEDVNEFYVCLMCQSFAPTHVCVITPDRPSLCGSITWHDAKAAYKIDPEGPIFPIEKG
ECLDPEAGEYEGVNEAVKEHSQGTVERVYLHSCLEYPHTSCGCFQAVVFYIPEVDGFGIVDREYPGETPIGLPFSTMAGE
ASGGEQQPGFVGVSYGYMESDKFLQYDGGWERVVWMPKALKERMKHAIPDELYDKIATEEDATTVEELREFLEKVEHPVV
ERWAEEEEEEEEKAPEEEAPAEEPTMEVKELPIAPGGGLNVKIVLKNAKIYAEKVIIKRADREDKS

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2)

COG id: COG1614

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdhC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDB_METKA (Q8TXF4)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614004.1
- ProteinModelPortal:   Q8TXF4
- SMR:   Q8TXF4
- GeneID:   1476821
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0720
- NMPDR:   fig|190192.1.peg.717
- HOGENOM:   HBG456963
- OMA:   DRPALCG
- ProtClustDB:   PRK04456
- BioCyc:   MKAN190192:MK0720-MONOMER
- HAMAP:   MF_01138
- InterPro:   IPR004461
- InterPro:   IPR011254
- TIGRFAMs:   TIGR00316

Pfam domain/function: PF03598 CdhC; SSF56821 Prismane_like

EC number: 1.2.99.2

Molecular weight: Translated: 53016; Mature: 52885

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLADLPVDVSPRHEGERIRSGDMYVELAGPKSFGAELFKVVDPDEIEPDKVEVIGPDI
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEECCCH
DEMEEGGRYPFAIYVKAAGEELEEDVEGVLERRIHEFCNYVEGFMHLNQRDQIWCRVSKN
HHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
VTEKGFRLEHLGIALRELYKEEFGNVIDSVEVTIMTDEEKVEEFLEYARRVYKKRDERAK
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHC
GLSEEDVNEFYVCLMCQSFAPTHVCVITPDRPSLCGSITWHDAKAAYKIDPEGPIFPIEK
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCEEEEECCCCCEECCCC
GECLDPEAGEYEGVNEAVKEHSQGTVERVYLHSCLEYPHTSCGCFQAVVFYIPEVDGFGI
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
VDREYPGETPIGLPFSTMAGEASGGEQQPGFVGVSYGYMESDKFLQYDGGWERVVWMPKA
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCEEEECHHH
LKERMKHAIPDELYDKIATEEDATTVEELREFLEKVEHPVVERWAEEEEEEEEKAPEEEA
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PAEEPTMEVKELPIAPGGGLNVKIVLKNAKIYAEKVIIKRADREDKS
CCCCCCCHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSLADLPVDVSPRHEGERIRSGDMYVELAGPKSFGAELFKVVDPDEIEPDKVEVIGPDI
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEECCCH
DEMEEGGRYPFAIYVKAAGEELEEDVEGVLERRIHEFCNYVEGFMHLNQRDQIWCRVSKN
HHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
VTEKGFRLEHLGIALRELYKEEFGNVIDSVEVTIMTDEEKVEEFLEYARRVYKKRDERAK
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHC
GLSEEDVNEFYVCLMCQSFAPTHVCVITPDRPSLCGSITWHDAKAAYKIDPEGPIFPIEK
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCEEEEECCCCCEECCCC
GECLDPEAGEYEGVNEAVKEHSQGTVERVYLHSCLEYPHTSCGCFQAVVFYIPEVDGFGI
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
VDREYPGETPIGLPFSTMAGEASGGEQQPGFVGVSYGYMESDKFLQYDGGWERVVWMPKA
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCEEEECHHH
LKERMKHAIPDELYDKIATEEDATTVEELREFLEKVEHPVVERWAEEEEEEEEKAPEEEA
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PAEEPTMEVKELPIAPGGGLNVKIVLKNAKIYAEKVIIKRADREDKS
CCCCCCCHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CO; H2O; A

Specific reaction: CO + H2O + A = CO2 + AH2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014