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The map label for this gene is NhaP [C]

Identifier: 20093990

GI number: 20093990

Start: 514237

End: 515541

Strand: Direct

Name: NhaP [C]

Synonym: MK0552

Alternate gene names: 20093990

Gene position: 514237-515541 (Clockwise)

Preceding gene: 20093989

Following gene: 20093991

Centisome position: 30.34

GC content: 55.56

Gene sequence:

>1305_bases
ATGTGGCGAACTGTAAAGATGGGGGGTAGCACGACGAAGTTCGGGTTCTTCACCCTCGTAGGTTACACGGCGTTACTCCT
GTCCTTAGGAGCGATCGTCGCGAGACTGTCCGAAGACAGGGGCCTCCCGGACATACCGTTCTTGCTCCTCCTCGGATTCT
TGCTGGGCCCCATCGCCGGGATCGTACGTCCCGAGTACGCCCAGAAGGCGTTTCCGTTCGTGGGTACGCTAGGACTCATC
ATCATACTGCTCGACGGTGGATTCGAGATCGGTATCGACGTCCTGCGTCGCGTAGCCTCTCTCGTGGCGAAGTTAGACTC
GATAACCCTACTGATAACGGCCGGGATATCCTCTCTGATATTCAACCTCGTGTTCGGGCTGAAACCCTTCAGCCCGATAG
GGTTCCTGTACGGCTCGATAACGTGTGCTACCGATCCGGCGACGTTGATCCCCGTATTCTCGAAGGTGGAGTTGCCTATC
AACATTTCGACAGCTTTAATAGCCGAAAGCGTGTTCAACGATCCGCTAGGAGTCGTGCTGACCAAGATGTCACTGTCAGT
GATGGGATTAAGCAGCCACCAGAATCCGATCCTGTTGTTCATCTCGTTAGCCGCAGGAGGAGCCGCCCTAGGCTTAGCCA
CCGGCGTGGTCCTCGAGCGATTGCTCGCCAGAGAGCCGTTCGGAGAGTATGTGGTACCCATAACCTTAGGAGCAGCCCTA
GCGCTCTGGTACATATGCGAGGAGCTACTCCCTGGGTTGCTTGGATACGAGCTGAGCGGATTCATGGCGGTGGCAGTACT
TGGGATGTACCTGGGCAACAACTTGATCAAGCACGACTATCTGAAGGACGATCGGACGTTCCTCAAGGACTTCTTCGAAG
AACTTTCCACAGTAGTCCGTATCATGGTGTTCACCCTCCTCGGAGCCTGCGTCAGCATTTCGCTGCTGAAGACGTTCTGG
CTCAAGGGACTAGTATGCGCACTGAGCAACGTCTTCATCGCGCGGCCTGCAGGAGTCATCATCGGAACATACATACCACC
GAAGGAGGACTTGAACCTGAAAGAGCGGATTTACCTGGCGCTCGAAGGACCGCGAGGGGTAGTACCGGCGGCTCTGGTAG
GCACGATTTACTCCAAGATAGTATCTAACCCGCACGCGGTACCGGTAGCGATCGCCAGCGAGATGCCACCTAAGACCTTA
GCCAGCGCCATTCTAGTGACCACGTTCCTCACGATATTCATCAGCGTGGTTCTCGAAGCTACATGGGCTCAACCGCTGGC
GAAGCGTCTTCTGAAGGAGGAGTAA

Upstream 100 bases:

>100_bases
CGATGCGTCACGAGGAGTTACCATTATACGGGGTCCAGTTCCACCCCGAGCTGAAGTTCACCGAGTACGGGCCGGATATA
CTGAAGAACTTCGCGAAACT

Downstream 100 bases:

>100_bases
CCCTCCGTCTGAGGAAAACTCGTCATCGCTCGGCAGGGGAGTGACTCTTCATCGGGGGAAAAACTTTGCCCGTCGAGAAG
CACGTCGAACGAGCCCCGAA

Product: NhaP-type Na+/H+ or K+/H+ antiporter

Products: NA

Alternate protein names: MjNhaP2 [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MWRTVKMGGSTTKFGFFTLVGYTALLLSLGAIVARLSEDRGLPDIPFLLLLGFLLGPIAGIVRPEYAQKAFPFVGTLGLI
IILLDGGFEIGIDVLRRVASLVAKLDSITLLITAGISSLIFNLVFGLKPFSPIGFLYGSITCATDPATLIPVFSKVELPI
NISTALIAESVFNDPLGVVLTKMSLSVMGLSSHQNPILLFISLAAGGAALGLATGVVLERLLAREPFGEYVVPITLGAAL
ALWYICEELLPGLLGYELSGFMAVAVLGMYLGNNLIKHDYLKDDRTFLKDFFEELSTVVRIMVFTLLGACVSISLLKTFW
LKGLVCALSNVFIARPAGVIIGTYIPPKEDLNLKERIYLALEGPRGVVPAALVGTIYSKIVSNPHAVPVAIASEMPPKTL
ASAILVTTFLTIFISVVLEATWAQPLAKRLLKEE

Sequences:

>Translated_434_residues
MWRTVKMGGSTTKFGFFTLVGYTALLLSLGAIVARLSEDRGLPDIPFLLLLGFLLGPIAGIVRPEYAQKAFPFVGTLGLI
IILLDGGFEIGIDVLRRVASLVAKLDSITLLITAGISSLIFNLVFGLKPFSPIGFLYGSITCATDPATLIPVFSKVELPI
NISTALIAESVFNDPLGVVLTKMSLSVMGLSSHQNPILLFISLAAGGAALGLATGVVLERLLAREPFGEYVVPITLGAAL
ALWYICEELLPGLLGYELSGFMAVAVLGMYLGNNLIKHDYLKDDRTFLKDFFEELSTVVRIMVFTLLGACVSISLLKTFW
LKGLVCALSNVFIARPAGVIIGTYIPPKEDLNLKERIYLALEGPRGVVPAALVGTIYSKIVSNPHAVPVAIASEMPPKTL
ASAILVTTFLTIFISVVLEATWAQPLAKRLLKEE
>Mature_434_residues
MWRTVKMGGSTTKFGFFTLVGYTALLLSLGAIVARLSEDRGLPDIPFLLLLGFLLGPIAGIVRPEYAQKAFPFVGTLGLI
IILLDGGFEIGIDVLRRVASLVAKLDSITLLITAGISSLIFNLVFGLKPFSPIGFLYGSITCATDPATLIPVFSKVELPI
NISTALIAESVFNDPLGVVLTKMSLSVMGLSSHQNPILLFISLAAGGAALGLATGVVLERLLAREPFGEYVVPITLGAAL
ALWYICEELLPGLLGYELSGFMAVAVLGMYLGNNLIKHDYLKDDRTFLKDFFEELSTVVRIMVFTLLGACVSISLLKTFW
LKGLVCALSNVFIARPAGVIIGTYIPPKEDLNLKERIYLALEGPRGVVPAALVGTIYSKIVSNPHAVPVAIASEMPPKTL
ASAILVTTFLTIFISVVLEATWAQPLAKRLLKEE

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=336, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221510740, Length=310, Percent_Identity=24.8387096774194, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 46556; Mature: 46556

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRTVKMGGSTTKFGFFTLVGYTALLLSLGAIVARLSEDRGLPDIPFLLLLGFLLGPIAG
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IVRPEYAQKAFPFVGTLGLIIILLDGGFEIGIDVLRRVASLVAKLDSITLLITAGISSLI
HCCCHHHHHHCCHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNLVFGLKPFSPIGFLYGSITCATDPATLIPVFSKVELPINISTALIAESVFNDPLGVVL
HHHHHCCCCCCCHHHHHHCEEECCCCHHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHH
TKMSLSVMGLSSHQNPILLFISLAAGGAALGLATGVVLERLLAREPFGEYVVPITLGAAL
HHHHHHHEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
ALWYICEELLPGLLGYELSGFMAVAVLGMYLGNNLIKHDYLKDDRTFLKDFFEELSTVVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
IMVFTLLGACVSISLLKTFWLKGLVCALSNVFIARPAGVIIGTYIPPKEDLNLKERIYLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEE
LEGPRGVVPAALVGTIYSKIVSNPHAVPVAIASEMPPKTLASAILVTTFLTIFISVVLEA
EECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TWAQPLAKRLLKEE
HHHHHHHHHHHCCC
>Mature Secondary Structure
MWRTVKMGGSTTKFGFFTLVGYTALLLSLGAIVARLSEDRGLPDIPFLLLLGFLLGPIAG
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IVRPEYAQKAFPFVGTLGLIIILLDGGFEIGIDVLRRVASLVAKLDSITLLITAGISSLI
HCCCHHHHHHCCHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNLVFGLKPFSPIGFLYGSITCATDPATLIPVFSKVELPINISTALIAESVFNDPLGVVL
HHHHHCCCCCCCHHHHHHCEEECCCCHHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHH
TKMSLSVMGLSSHQNPILLFISLAAGGAALGLATGVVLERLLAREPFGEYVVPITLGAAL
HHHHHHHEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
ALWYICEELLPGLLGYELSGFMAVAVLGMYLGNNLIKHDYLKDDRTFLKDFFEELSTVVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
IMVFTLLGACVSISLLKTFWLKGLVCALSNVFIARPAGVIIGTYIPPKEDLNLKERIYLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEE
LEGPRGVVPAALVGTIYSKIVSNPHAVPVAIASEMPPKTLASAILVTTFLTIFISVVLEA
EECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TWAQPLAKRLLKEE
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]