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The map label for this gene is MoaB [H]

Identifier: 20093991

GI number: 20093991

Start: 515607

End: 516128

Strand: Direct

Name: MoaB [H]

Synonym: MK0553

Alternate gene names: 20093991

Gene position: 515607-516128 (Clockwise)

Preceding gene: 20093990

Following gene: 20093993

Centisome position: 30.42

GC content: 60.73

Gene sequence:

>522_bases
TTGCCCGTCGAGAAGCACGTCGAACGAGCCCCGAAGCGACTAGCCATCGCCGTAATCACCGTCAGTACGTCCAAATTCGA
GGAAGCGGCGCGCGGCGAAGAACCCGAGGACACTTCCGGAGATATCCTTGAATCACGGTTCGAGCAGGCGGGCCATGAGA
CGCGCTACCGAGTGCTGATACCCGACCAGAGGGAAATGGTGGCCGGAGCTGTCAAGTGGACCGCCAATCGCGTGGACGCT
GTCGTGACGACGGGAGGTACCGGACTCACTCCGACAGACGTGACGATCGAAGCCGTAGGTGAGATCGCGGAAAAGCAGGT
GCCTGGCTTCGGAGAACTGTTCCGGAGGAAATCCGAAGAAGACGTCGGCGCTCACTCGATCTTGAGTCGGGCCGAGATGT
TCGTCGTCGACGGCACACCGGTGGCGTGTCTACCGGGGTCGCCGAACGCGGTGAAGTTAGGAGCGGAACTCCTCATCGAG
GTGTTACCGCATGTTGTCGTTCATAGCCGCGGCGACGTTTAG

Upstream 100 bases:

>100_bases
AACCGCTGGCGAAGCGTCTTCTGAAGGAGGAGTAACCCTCCGTCTGAGGAAAACTCGTCATCGCTCGGCAGGGGAGTGAC
TCTTCATCGGGGGAAAAACT

Downstream 100 bases:

>100_bases
GGGGAACTTACTCCTTCTCTTTGATGATTTTCTCCACCACCCTAACGTTCTCGATGCGGGTGTGTGGGTACTGCCCCTCT
TCGTCCTTCTCAGCGTACTT

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MPVEKHVERAPKRLAIAVITVSTSKFEEAARGEEPEDTSGDILESRFEQAGHETRYRVLIPDQREMVAGAVKWTANRVDA
VVTTGGTGLTPTDVTIEAVGEIAEKQVPGFGELFRRKSEEDVGAHSILSRAEMFVVDGTPVACLPGSPNAVKLGAELLIE
VLPHVVVHSRGDV

Sequences:

>Translated_173_residues
MPVEKHVERAPKRLAIAVITVSTSKFEEAARGEEPEDTSGDILESRFEQAGHETRYRVLIPDQREMVAGAVKWTANRVDA
VVTTGGTGLTPTDVTIEAVGEIAEKQVPGFGELFRRKSEEDVGAHSILSRAEMFVVDGTPVACLPGSPNAVKLGAELLIE
VLPHVVVHSRGDV
>Mature_172_residues
PVEKHVERAPKRLAIAVITVSTSKFEEAARGEEPEDTSGDILESRFEQAGHETRYRVLIPDQREMVAGAVKWTANRVDAV
VTTGGTGLTPTDVTIEAVGEIAEKQVPGFGELFRRKSEEDVGAHSILSRAEMFVVDGTPVACLPGSPNAVKLGAELLIEV
LPHVVVHSRGDV

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Escherichia coli, GI1787000, Length=146, Percent_Identity=36.986301369863, Blast_Score=81, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18635; Mature: 18504

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVEKHVERAPKRLAIAVITVSTSKFEEAARGEEPEDTSGDILESRFEQAGHETRYRVLI
CCCHHHHHHCCHHEEEEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEC
PDQREMVAGAVKWTANRVDAVVTTGGTGLTPTDVTIEAVGEIAEKQVPGFGELFRRKSEE
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCC
DVGAHSILSRAEMFVVDGTPVACLPGSPNAVKLGAELLIEVLPHVVVHSRGDV
CCHHHHHHHHCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PVEKHVERAPKRLAIAVITVSTSKFEEAARGEEPEDTSGDILESRFEQAGHETRYRVLI
CCHHHHHHCCHHEEEEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEC
PDQREMVAGAVKWTANRVDAVVTTGGTGLTPTDVTIEAVGEIAEKQVPGFGELFRRKSEE
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCC
DVGAHSILSRAEMFVVDGTPVACLPGSPNAVKLGAELLIEVLPHVVVHSRGDV
CCHHHHHHHHCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA