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The map label for this gene is dppB [H]

Identifier: 18977781

GI number: 18977781

Start: 1324943

End: 1325941

Strand: Direct

Name: dppB [H]

Synonym: PF1409

Alternate gene names: 18977781

Gene position: 1324943-1325941 (Clockwise)

Preceding gene: 18977780

Following gene: 18977782

Centisome position: 69.43

GC content: 40.74

Gene sequence:

>999_bases
ATGGCGAACCTCAAGAAATTCTTAATTAGGAGGCTACTAACTTTTATTCCAACAATAATAGGAGTTACAATAATAGTATT
TCTAATAGCATATAAAATACCAGCAGATCCAGCCAAGGCATGGGCAGGAGGAGAGAAAGCAACTCAAGCTGCAATTGAAA
GGATAATAAGAGAATATCACCTAGACAAGCCTTGGTATGATCAGTATATCTTTTTAATGAAAGGACTACTTACAAATACA
ATTATCGACCCCAGAACGTCAAACCCTGTTATGTATGACGTTGGAAAAAGATTTCCAGTAACTTTTCAGTTGGCAATAAT
AGCGTTTGTCTTCATTCTTCTCGTAGGAATTCCACTAGGAATAATCTCTGCCCTTAAAAGGAATACATGGATAGACACAG
TGGTAAGAATATTTGCCCTCCTGGGTGTTTCAACTCCAGCATTTTGGCTAGGATACCTAATGCTGTACGTCTTCTTTGTG
AAATACAGAATTACCACAATAGCAGGTGTCCCACCATTTCCACCAAAGATTACGGGAGTTCCCATGATAGATGCTTTACT
AAGGGGCGATTTTGCACTGTTTAAGCAACACTTAGCAAGATTCTGGCTCCCAGGCTTCACTCTTGGCTTCCTGGGAATGG
GAGTAACAGCTAGATTCGTGAGAAATAGTTTCCTTGAGGCACTTAGCTCAGACTTTGTTCAGTTTTTGAAGGCCAAAGGA
GTACCAAAGCTTAGGCTTTATAGGCACGCCCTAAAGAATGCATTAGTTCCGATAGTTACTGTGCTCGGCCTCCAATTCGG
TGGACTTCTTGGAGGAACACCAATTACTGAGACTGTGTTTGGGCTCCCAGGAATGGGTAGTTATGCGGTACAATCCATTC
AAAACTTAGACTTCCCAGTCGTGGTAGCTATAACTTTCATATACGCTATAATCTACGTGGTAACTAACCTCGTCGTTGAT
ATACTCTATGCTATAATAGATCCAAGGGTTAGATACTGA

Upstream 100 bases:

>100_bases
TTTGTCTTTCTGTCTTTTCATATACCGAAGGATTTTTATTTTGTTGACAAAAAAGTTTAGACGAAAATTTTAATGCGACA
ATGAACATGGAGGGACATAG

Downstream 100 bases:

>100_bases
GGTGATTTCAAATGCAGGAAGAGTATAAGAAGTCTATACTTGACAAACTTGCCGATAAATTCGTTTATGGTCTTGGAAAG
TTCATAAGTTTATTTAAAAA

Product: dipeptide transport system permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MANLKKFLIRRLLTFIPTIIGVTIIVFLIAYKIPADPAKAWAGGEKATQAAIERIIREYHLDKPWYDQYIFLMKGLLTNT
IIDPRTSNPVMYDVGKRFPVTFQLAIIAFVFILLVGIPLGIISALKRNTWIDTVVRIFALLGVSTPAFWLGYLMLYVFFV
KYRITTIAGVPPFPPKITGVPMIDALLRGDFALFKQHLARFWLPGFTLGFLGMGVTARFVRNSFLEALSSDFVQFLKAKG
VPKLRLYRHALKNALVPIVTVLGLQFGGLLGGTPITETVFGLPGMGSYAVQSIQNLDFPVVVAITFIYAIIYVVTNLVVD
ILYAIIDPRVRY

Sequences:

>Translated_332_residues
MANLKKFLIRRLLTFIPTIIGVTIIVFLIAYKIPADPAKAWAGGEKATQAAIERIIREYHLDKPWYDQYIFLMKGLLTNT
IIDPRTSNPVMYDVGKRFPVTFQLAIIAFVFILLVGIPLGIISALKRNTWIDTVVRIFALLGVSTPAFWLGYLMLYVFFV
KYRITTIAGVPPFPPKITGVPMIDALLRGDFALFKQHLARFWLPGFTLGFLGMGVTARFVRNSFLEALSSDFVQFLKAKG
VPKLRLYRHALKNALVPIVTVLGLQFGGLLGGTPITETVFGLPGMGSYAVQSIQNLDFPVVVAITFIYAIIYVVTNLVVD
ILYAIIDPRVRY
>Mature_331_residues
ANLKKFLIRRLLTFIPTIIGVTIIVFLIAYKIPADPAKAWAGGEKATQAAIERIIREYHLDKPWYDQYIFLMKGLLTNTI
IDPRTSNPVMYDVGKRFPVTFQLAIIAFVFILLVGIPLGIISALKRNTWIDTVVRIFALLGVSTPAFWLGYLMLYVFFVK
YRITTIAGVPPFPPKITGVPMIDALLRGDFALFKQHLARFWLPGFTLGFLGMGVTARFVRNSFLEALSSDFVQFLKAKGV
PKLRLYRHALKNALVPIVTVLGLQFGGLLGGTPITETVFGLPGMGSYAVQSIQNLDFPVVVAITFIYAIIYVVTNLVVDI
LYAIIDPRVRY

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=34.5238095238095, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1787761, Length=332, Percent_Identity=41.566265060241, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI1787053, Length=329, Percent_Identity=35.5623100303951, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789888, Length=330, Percent_Identity=33.030303030303, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1787497, Length=331, Percent_Identity=31.1178247734139, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1787550, Length=276, Percent_Identity=31.1594202898551, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788504, Length=369, Percent_Identity=25.4742547425474, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37153; Mature: 37022

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLKKFLIRRLLTFIPTIIGVTIIVFLIAYKIPADPAKAWAGGEKATQAAIERIIREYH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHC
LDKPWYDQYIFLMKGLLTNTIIDPRTSNPVMYDVGKRFPVTFQLAIIAFVFILLVGIPLG
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
IISALKRNTWIDTVVRIFALLGVSTPAFWLGYLMLYVFFVKYRITTIAGVPPFPPKITGV
HHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PMIDALLRGDFALFKQHLARFWLPGFTLGFLGMGVTARFVRNSFLEALSSDFVQFLKAKG
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VPKLRLYRHALKNALVPIVTVLGLQFGGLLGGTPITETVFGLPGMGSYAVQSIQNLDFPV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCCHH
VVAITFIYAIIYVVTNLVVDILYAIIDPRVRY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ANLKKFLIRRLLTFIPTIIGVTIIVFLIAYKIPADPAKAWAGGEKATQAAIERIIREYH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHC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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9680333 [H]