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The map label for this gene is appC [H]

Identifier: 18977782

GI number: 18977782

Start: 1325953

End: 1327104

Strand: Direct

Name: appC [H]

Synonym: PF1410

Alternate gene names: 18977782

Gene position: 1325953-1327104 (Clockwise)

Preceding gene: 18977781

Following gene: 18977783

Centisome position: 69.49

GC content: 41.23

Gene sequence:

>1152_bases
ATGCAGGAAGAGTATAAGAAGTCTATACTTGACAAACTTGCCGATAAATTCGTTTATGGTCTTGGAAAGTTCATAAGTTT
ATTTAAAAAAGGCTGGATGGAAAAAAACAGGTCAAAGCTTGAAGAATGGAGATTAATGCTTTATGCCTTAAACAGGTCAC
CTCCAGCATTAATAGGACTGTTTCTTGTAATGATTTTTATCTTCCTGGGAATCTTTGGACCGTATCTAGCTCCTTGGAAG
TACAACTTCATGCCAACATTATATACAAGCAACTATGACCAAGTTTATCTCGTACCCCCTGGGAGTAAAGCGGTGCTAGA
GTACTATAATAACGCAGTAATAACTTATCCGTTAGGCTCCGATCATTATGGAAGAGATCTATTAAGTTTGATCCTACAAG
GAGCAAGGACGAGCTTTGTAATTTCAATAATAGTTATTATCTTGGGAGTCCCCCTGGGAATAATTTTGGGACTAATTGCA
GGATATTACGGAGGAAAGATAGACGAACTAATAATGCGTATAACTGACATGTTCCTGTCTTTTCCAGCGTTAATCTTGGC
AATAGCACTTTCGGCAGTATTACCTGAGAGACTACAAGAGTTTATCTCAGCACATCCTATTCTAGAGAAAATAGTGCTGG
CAATCTTTGCTCTAGACCAGAGAGAAGCAGGGAACCTTGGAAGGTTGCTTGCTGTTATAGTGGCAATGATTATAGTATGG
TGGCCAGGATACGCAAGAATCACTAGAGGTTCAACGTTGGCTGAGAGAGAAAAATTATATATCGAAGCTGCTAGAGCAAT
TGGCCTTCCAACAAGAACTATACTCTTCAAGCACATCCTGCCAAACATCATTGGGCCAATATTAGTGTACATAACCCTAG
ATTTCGGTAGCGTAGTTTTAATGGAAGCTGGACTAAGCTTCCTGGGACTCGGTGCAACACCACCAATTGCAGACTGGGGA
AGAATAGTATACGATGGAGCCCAGTACTTCCCAAGGTGCTGGTGGCTAGTGTTTTACCCAGGATTGGTAGTTCTCTTAAC
AGCGCTTGGATGGAACTTACTTGGTGATGGCCTAAGAGATATCCTGGATCCAAAGACCAGAAGAAGCATAGAGTTCAAGG
TAAAGAAGAAGGAGGGTGAGAAAAGTGCCTGA

Upstream 100 bases:

>100_bases
TAACTTTCATATACGCTATAATCTACGTGGTAACTAACCTCGTCGTTGATATACTCTATGCTATAATAGATCCAAGGGTT
AGATACTGAGGTGATTTCAA

Downstream 100 bases:

>100_bases
GCCCATCCTCCAAGTTAGAAATCTAACTGTTCACTTTTATACTTACGCTGGAATAGTTAAAGCCATAGAAAAAGTGTCTT
TCGACGTGTACAAAGGAGAG

Product: dipeptide transport system permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MQEEYKKSILDKLADKFVYGLGKFISLFKKGWMEKNRSKLEEWRLMLYALNRSPPALIGLFLVMIFIFLGIFGPYLAPWK
YNFMPTLYTSNYDQVYLVPPGSKAVLEYYNNAVITYPLGSDHYGRDLLSLILQGARTSFVISIIVIILGVPLGIILGLIA
GYYGGKIDELIMRITDMFLSFPALILAIALSAVLPERLQEFISAHPILEKIVLAIFALDQREAGNLGRLLAVIVAMIIVW
WPGYARITRGSTLAEREKLYIEAARAIGLPTRTILFKHILPNIIGPILVYITLDFGSVVLMEAGLSFLGLGATPPIADWG
RIVYDGAQYFPRCWWLVFYPGLVVLLTALGWNLLGDGLRDILDPKTRRSIEFKVKKKEGEKSA

Sequences:

>Translated_383_residues
MQEEYKKSILDKLADKFVYGLGKFISLFKKGWMEKNRSKLEEWRLMLYALNRSPPALIGLFLVMIFIFLGIFGPYLAPWK
YNFMPTLYTSNYDQVYLVPPGSKAVLEYYNNAVITYPLGSDHYGRDLLSLILQGARTSFVISIIVIILGVPLGIILGLIA
GYYGGKIDELIMRITDMFLSFPALILAIALSAVLPERLQEFISAHPILEKIVLAIFALDQREAGNLGRLLAVIVAMIIVW
WPGYARITRGSTLAEREKLYIEAARAIGLPTRTILFKHILPNIIGPILVYITLDFGSVVLMEAGLSFLGLGATPPIADWG
RIVYDGAQYFPRCWWLVFYPGLVVLLTALGWNLLGDGLRDILDPKTRRSIEFKVKKKEGEKSA
>Mature_383_residues
MQEEYKKSILDKLADKFVYGLGKFISLFKKGWMEKNRSKLEEWRLMLYALNRSPPALIGLFLVMIFIFLGIFGPYLAPWK
YNFMPTLYTSNYDQVYLVPPGSKAVLEYYNNAVITYPLGSDHYGRDLLSLILQGARTSFVISIIVIILGVPLGIILGLIA
GYYGGKIDELIMRITDMFLSFPALILAIALSAVLPERLQEFISAHPILEKIVLAIFALDQREAGNLGRLLAVIVAMIIVW
WPGYARITRGSTLAEREKLYIEAARAIGLPTRTILFKHILPNIIGPILVYITLDFGSVVLMEAGLSFLGLGATPPIADWG
RIVYDGAQYFPRCWWLVFYPGLVVLLTALGWNLLGDGLRDILDPKTRRSIEFKVKKKEGEKSA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=328, Percent_Identity=33.5365853658537, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787760, Length=321, Percent_Identity=33.6448598130841, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789964, Length=302, Percent_Identity=34.4370860927152, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789889, Length=248, Percent_Identity=33.0645161290323, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787498, Length=318, Percent_Identity=31.4465408805031, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1787549, Length=304, Percent_Identity=28.6184210526316, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788505, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43089; Mature: 43089

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEEYKKSILDKLADKFVYGLGKFISLFKKGWMEKNRSKLEEWRLMLYALNRSPPALIGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
FLVMIFIFLGIFGPYLAPWKYNFMPTLYTSNYDQVYLVPPGSKAVLEYYNNAVITYPLGS
HHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHCCEEEEECCCC
DHYGRDLLSLILQGARTSFVISIIVIILGVPLGIILGLIAGYYGGKIDELIMRITDMFLS
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FPALILAIALSAVLPERLQEFISAHPILEKIVLAIFALDQREAGNLGRLLAVIVAMIIVW
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
WPGYARITRGSTLAEREKLYIEAARAIGLPTRTILFKHILPNIIGPILVYITLDFGSVVL
CCCHHHEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MEAGLSFLGLGATPPIADWGRIVYDGAQYFPRCWWLVFYPGLVVLLTALGWNLLGDGLRD
HHHCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDPKTRRSIEFKVKKKEGEKSA
HCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MQEEYKKSILDKLADKFVYGLGKFISLFKKGWMEKNRSKLEEWRLMLYALNRSPPALIGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
FLVMIFIFLGIFGPYLAPWKYNFMPTLYTSNYDQVYLVPPGSKAVLEYYNNAVITYPLGS
HHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHCCEEEEECCCC
DHYGRDLLSLILQGARTSFVISIIVIILGVPLGIILGLIAGYYGGKIDELIMRITDMFLS
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FPALILAIALSAVLPERLQEFISAHPILEKIVLAIFALDQREAGNLGRLLAVIVAMIIVW
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
WPGYARITRGSTLAEREKLYIEAARAIGLPTRTILFKHILPNIIGPILVYITLDFGSVVL
CCCHHHEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MEAGLSFLGLGATPPIADWGRIVYDGAQYFPRCWWLVFYPGLVVLLTALGWNLLGDGLRD
HHHCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDPKTRRSIEFKVKKKEGEKSA
HCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]