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The map label for this gene is ipk [H]

Identifier: 18311194

GI number: 18311194

Start: 2532078

End: 2532944

Strand: Reverse

Name: ipk [H]

Synonym: CPE2212

Alternate gene names: 18311194

Gene position: 2532944-2532078 (Counterclockwise)

Preceding gene: 18311195

Following gene: 18311193

Centisome position: 83.56

GC content: 27.22

Gene sequence:

>867_bases
ATGAAAATGAAGGCTTATGCAAAAATAAATATAGCCTTAGATGCTATTGGAAAAAGAGAAGATAACTATCATTTATTAAG
AATGATAATGCAAACAGTAGATTTGTATGACGTTATAGATATAGAGAAAAGTAATGATAGTAATATAAGCATTTCTTGTA
ATAAGCATTATGTCTCTACAGATGAAAGAAACTTAGCATACAAAGCGGCAGTGTTATTTAGAGATGAATTTAATATAAAA
GATGGTGTAAAAATTAATATTAAGAAGAATATACCTGTAGCTGCAGGTATGGCGGGTGGAAGTACTAATGCGGCGGCAGT
TTTAGTTATAATGAATAAGCTTTTTAATGTAAATGCTAGTTTAGAAGTGTTAAAAGAAATAGGACTAAAAATAGGAGCAG
ATGTTCCATATTGTATTGAAGGTGGAACTGCTTTATGTGAAGGAATTGGAGAGATTATAACACCTTTAAAACCTTTTGAA
AATAAAATATTAGTTGTATTAAAACCTAATTTTGGGGTATCTACTAAAGAAGTTTATACAAACTTAGATATAAATAAGAT
AAGAAAACATGTTAATATAGAAGGCTTAATTCAAGCTATGGAAAATGATGATTTAGATTATGTATCAAAAAATATGAAAA
ATGTTTTAGAAAATGTAACTTTAAAGAAGCATACTATATTAAAAAATATAAAAGAAGATATGAGAAAAAGTGGAGCCTTA
GGTGCAATGATGAGTGGAAGTGGACCTACTGTATTTGCTTTTTTTGATGATATGCTAACAGCTCAAAGAGCTTTTGAATT
TTTAAAAGGAAAATATAAATATTCAGATGTATATATAACAAGAACTATAAATAGCAATAATTTATAA

Upstream 100 bases:

>100_bases
AATTTAGAAGATTTCTCTTTATTTTAATTAACTCTTTATGTTTTTAGAAGAAAATAATATAATTATATTTAGCTTTAATT
AATGTAAGAAGGGTGATTAT

Downstream 100 bases:

>100_bases
AAAAATATTTTTTTATTGTATATAAAAAATACTCCTTGGTAATAATCAAGGTATCAGGGGGTGTTTGTTATGAAAAAAAT
ATTATCAGTTTTATTTTTAG

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKMKAYAKINIALDAIGKREDNYHLLRMIMQTVDLYDVIDIEKSNDSNISISCNKHYVSTDERNLAYKAAVLFRDEFNIK
DGVKINIKKNIPVAAGMAGGSTNAAAVLVIMNKLFNVNASLEVLKEIGLKIGADVPYCIEGGTALCEGIGEIITPLKPFE
NKILVVLKPNFGVSTKEVYTNLDINKIRKHVNIEGLIQAMENDDLDYVSKNMKNVLENVTLKKHTILKNIKEDMRKSGAL
GAMMSGSGPTVFAFFDDMLTAQRAFEFLKGKYKYSDVYITRTINSNNL

Sequences:

>Translated_288_residues
MKMKAYAKINIALDAIGKREDNYHLLRMIMQTVDLYDVIDIEKSNDSNISISCNKHYVSTDERNLAYKAAVLFRDEFNIK
DGVKINIKKNIPVAAGMAGGSTNAAAVLVIMNKLFNVNASLEVLKEIGLKIGADVPYCIEGGTALCEGIGEIITPLKPFE
NKILVVLKPNFGVSTKEVYTNLDINKIRKHVNIEGLIQAMENDDLDYVSKNMKNVLENVTLKKHTILKNIKEDMRKSGAL
GAMMSGSGPTVFAFFDDMLTAQRAFEFLKGKYKYSDVYITRTINSNNL
>Mature_288_residues
MKMKAYAKINIALDAIGKREDNYHLLRMIMQTVDLYDVIDIEKSNDSNISISCNKHYVSTDERNLAYKAAVLFRDEFNIK
DGVKINIKKNIPVAAGMAGGSTNAAAVLVIMNKLFNVNASLEVLKEIGLKIGADVPYCIEGGTALCEGIGEIITPLKPFE
NKILVVLKPNFGVSTKEVYTNLDINKIRKHVNIEGLIQAMENDDLDYVSKNMKNVLENVTLKKHTILKNIKEDMRKSGAL
GAMMSGSGPTVFAFFDDMLTAQRAFEFLKGKYKYSDVYITRTINSNNL

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=294, Percent_Identity=29.5918367346939, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786184, Length=292, Percent_Identity=25.6849315068493, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 32087; Mature: 32087

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMKAYAKINIALDAIGKREDNYHLLRMIMQTVDLYDVIDIEKSNDSNISISCNKHYVST
CCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHCHHHEEEEECCCCCEEEEEECCEEECC
DERNLAYKAAVLFRDEFNIKDGVKINIKKNIPVAAGMAGGSTNAAAVLVIMNKLFNVNAS
CCCCCEEEEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCHH
LEVLKEIGLKIGADVPYCIEGGTALCEGIGEIITPLKPFENKILVVLKPNFGVSTKEVYT
HHHHHHCCCEECCCCCEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHC
NLDINKIRKHVNIEGLIQAMENDDLDYVSKNMKNVLENVTLKKHTILKNIKEDMRKSGAL
CCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
GAMMSGSGPTVFAFFDDMLTAQRAFEFLKGKYKYSDVYITRTINSNNL
EEEECCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCC
>Mature Secondary Structure
MKMKAYAKINIALDAIGKREDNYHLLRMIMQTVDLYDVIDIEKSNDSNISISCNKHYVST
CCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHCHHHEEEEECCCCCEEEEEECCEEECC
DERNLAYKAAVLFRDEFNIKDGVKINIKKNIPVAAGMAGGSTNAAAVLVIMNKLFNVNAS
CCCCCEEEEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCHH
LEVLKEIGLKIGADVPYCIEGGTALCEGIGEIITPLKPFENKILVVLKPNFGVSTKEVYT
HHHHHHCCCEECCCCCEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHC
NLDINKIRKHVNIEGLIQAMENDDLDYVSKNMKNVLENVTLKKHTILKNIKEDMRKSGAL
CCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
GAMMSGSGPTVFAFFDDMLTAQRAFEFLKGKYKYSDVYITRTINSNNL
EEEECCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA