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The map label for this gene is yqhQ [H]

Identifier: 18311185

GI number: 18311185

Start: 2522229

End: 2523938

Strand: Reverse

Name: yqhQ [H]

Synonym: CPE2203

Alternate gene names: 18311185

Gene position: 2523938-2522229 (Counterclockwise)

Preceding gene: 18311186

Following gene: 18311184

Centisome position: 83.26

GC content: 28.36

Gene sequence:

>1710_bases
ATCAAAAGGAAACAGCTACAGCAGGTTAGAACTCCAGAGGGAGATATAGAAGGTTCTTTTGAAAAAACTATACCATATAC
AAAGAAAAATAAAATTTTAGGACTACCTTTTATAAGAGGATTTGTAACTCTTATAGAGTCTTTAATTGTAGGATTAAAAT
CATTAAATTATTCAGCAAGTTTTTTTGATGATACAGAACCATCTAAATTTGAAGATTGGTTAAATAATAAATTTGGTGAA
AAAGCTAATAATGTAATAATGACACTTACAATTATGCTTTCCTTTGTATTTGCCATAATTTTATTTGTAGCAATACCAAC
TGGAATTACTTTTTTACTTAAAAAACTTAACCTTCCAGATTGGAGTTTAAGTGCTATTGAAGGAATCATAAGTATTGGTA
TGCTTTTAGGATACATGTACTTAATGGGAAAAGTAGATGATATAGAAAGAGTATTTCAATATCATGGAGCAGAACATAAG
ACTATATTCTGTTATGAGAATGAAGATGAACTTACAGTTGAAAATGTAAGAAAATATCCTAGATTTCATCCTAGATGTGG
AACAAACTTTCTATTTTTAGTTGCTATTGTAAGTATATTTATATTTTCCTTTACTAAATGGGATTCAGTTGCTCAGAGAA
CGGCTATAAGAGTAGCAATGTTACCAGTAATATCAGGAATAACTTATGAACTTATAAGATGGCTTGGCAAATCTCAAGGA
AATTTTGCAAAGATAATAGCAGCGCCAGGATTACAATTGCAAAAATTGACTACAAGGGAGCCTGATGATTCACAAATTGA
AGTAGCGATAGCTTCTTTAAGGAGGGCTGAAGGATTGAAAGAACCAAATAAAAAAGTTGGAGAATTATTAAATTTAGGAA
ATGAAACTTTAAAAGAAGTGGGTATAGATACATATATATTAGATACTCAATTATTATTAGGAAAAGTTTTAGAAAAAGAT
AAAATATGGCTTATAACTAATAAAAGTGAAGAAGTTAAAAAGTCAGATGAAATACATTTCTTAAATTTATTAGAAAAAAG
AAAATTAAAGATGCCTATGCAATATATTTTAGGAACTTGCGAATTCATGGGATTAGATTTTTATGTAGAAGAAGGAGTTT
TAATTCCAAGAGGAGATACTGAAATAATTGTAGAGGAAGTATTAAACAATATAGATGAAGATGCAGAAATTAATGTATGT
GATTTATGTTGTGGAAGTGGAGCTATAGGCTTATCTTTAGCTAATTATAGAAAGAATATTATTGTAGATTTAGTAGATAT
AGATGATATACCAGAAAAAGTTACAAGAAAAAATATAAGAGAATTAGAATTATCAAAAAGATGTGGCTTTATTAAGAGTG
ATCTTTTAAGTGAAGTCATTAAAAAAGGAAATAAGTATGATATTCTAGTTTCTAATCCACCATATATAAGAACAGAAGTA
ATAAATACTTTAATGGAAGATGTTAAAGATTATGAGCCGCACTTAGCTTTAGATGGGGGAGAAGATGGTTTAATATTCTA
TAGAAGAATTATTGATGAATCTTTAGAAGTATTAAAAGAAAATGGTATATTAGCTTTTGAAATAGGACATGATCAAGGTG
AGGATGTTAAAAATCTTATGATTGAAAAAGGATACTACGATGTTAAGGTCATAAAAGATTTAGCTGGTTTAGATAGATGT
GTTATAGGAAGAGTAAGCCTTGAAAGATAG

Upstream 100 bases:

>100_bases
AGGATTCTGATAATTAGTTAATGAAAGGATAGGGTTCAAATTATGAGAAAATGCCAAGTAAGGCGGTCAAGCAGTATTAG
GAAGGCGTTATGATGAGGGG

Downstream 100 bases:

>100_bases
CATAGTAGTGTGCTATAATTGTAAAATATGAAAATCTGTATACGGAGTGATAATAGATGATACTTGATAGATTAAATTTT
ATTGAAAATAAATATGATGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MKRKQLQQVRTPEGDIEGSFEKTIPYTKKNKILGLPFIRGFVTLIESLIVGLKSLNYSASFFDDTEPSKFEDWLNNKFGE
KANNVIMTLTIMLSFVFAIILFVAIPTGITFLLKKLNLPDWSLSAIEGIISIGMLLGYMYLMGKVDDIERVFQYHGAEHK
TIFCYENEDELTVENVRKYPRFHPRCGTNFLFLVAIVSIFIFSFTKWDSVAQRTAIRVAMLPVISGITYELIRWLGKSQG
NFAKIIAAPGLQLQKLTTREPDDSQIEVAIASLRRAEGLKEPNKKVGELLNLGNETLKEVGIDTYILDTQLLLGKVLEKD
KIWLITNKSEEVKKSDEIHFLNLLEKRKLKMPMQYILGTCEFMGLDFYVEEGVLIPRGDTEIIVEEVLNNIDEDAEINVC
DLCCGSGAIGLSLANYRKNIIVDLVDIDDIPEKVTRKNIRELELSKRCGFIKSDLLSEVIKKGNKYDILVSNPPYIRTEV
INTLMEDVKDYEPHLALDGGEDGLIFYRRIIDESLEVLKENGILAFEIGHDQGEDVKNLMIEKGYYDVKVIKDLAGLDRC
VIGRVSLER

Sequences:

>Translated_569_residues
MKRKQLQQVRTPEGDIEGSFEKTIPYTKKNKILGLPFIRGFVTLIESLIVGLKSLNYSASFFDDTEPSKFEDWLNNKFGE
KANNVIMTLTIMLSFVFAIILFVAIPTGITFLLKKLNLPDWSLSAIEGIISIGMLLGYMYLMGKVDDIERVFQYHGAEHK
TIFCYENEDELTVENVRKYPRFHPRCGTNFLFLVAIVSIFIFSFTKWDSVAQRTAIRVAMLPVISGITYELIRWLGKSQG
NFAKIIAAPGLQLQKLTTREPDDSQIEVAIASLRRAEGLKEPNKKVGELLNLGNETLKEVGIDTYILDTQLLLGKVLEKD
KIWLITNKSEEVKKSDEIHFLNLLEKRKLKMPMQYILGTCEFMGLDFYVEEGVLIPRGDTEIIVEEVLNNIDEDAEINVC
DLCCGSGAIGLSLANYRKNIIVDLVDIDDIPEKVTRKNIRELELSKRCGFIKSDLLSEVIKKGNKYDILVSNPPYIRTEV
INTLMEDVKDYEPHLALDGGEDGLIFYRRIIDESLEVLKENGILAFEIGHDQGEDVKNLMIEKGYYDVKVIKDLAGLDRC
VIGRVSLER
>Mature_569_residues
MKRKQLQQVRTPEGDIEGSFEKTIPYTKKNKILGLPFIRGFVTLIESLIVGLKSLNYSASFFDDTEPSKFEDWLNNKFGE
KANNVIMTLTIMLSFVFAIILFVAIPTGITFLLKKLNLPDWSLSAIEGIISIGMLLGYMYLMGKVDDIERVFQYHGAEHK
TIFCYENEDELTVENVRKYPRFHPRCGTNFLFLVAIVSIFIFSFTKWDSVAQRTAIRVAMLPVISGITYELIRWLGKSQG
NFAKIIAAPGLQLQKLTTREPDDSQIEVAIASLRRAEGLKEPNKKVGELLNLGNETLKEVGIDTYILDTQLLLGKVLEKD
KIWLITNKSEEVKKSDEIHFLNLLEKRKLKMPMQYILGTCEFMGLDFYVEEGVLIPRGDTEIIVEEVLNNIDEDAEINVC
DLCCGSGAIGLSLANYRKNIIVDLVDIDDIPEKVTRKNIRELELSKRCGFIKSDLLSEVIKKGNKYDILVSNPPYIRTEV
INTLMEDVKDYEPHLALDGGEDGLIFYRRIIDESLEVLKENGILAFEIGHDQGEDVKNLMIEKGYYDVKVIKDLAGLDRC
VIGRVSLER

Specific function: Methylates The Translation Termination Release Factor Rf1 On Gln-235 And Rf2 On Gln-252. [C]

COG id: COG3872

COG function: function code R; Predicted metal-dependent enzyme

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705409, Length=239, Percent_Identity=30.1255230125523, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1787463, Length=259, Percent_Identity=30.5019305019305, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87082085, Length=181, Percent_Identity=32.5966850828729, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324266, Length=199, Percent_Identity=30.6532663316583, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582226, Length=264, Percent_Identity=28.7878787878788, Blast_Score=111, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010787
- ProDom:   PD131510 [H]

Pfam domain/function: PF07136 DUF1385 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 64666; Mature: 64666

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure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HHCCCCHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]