Click here to switch to the map view.

The map label for this gene is tdk [H]

Identifier: 18311186

GI number: 18311186

Start: 2524022

End: 2524621

Strand: Reverse

Name: tdk [H]

Synonym: CPE2204

Alternate gene names: 18311186

Gene position: 2524621-2524022 (Counterclockwise)

Preceding gene: 18311189

Following gene: 18311185

Centisome position: 83.28

GC content: 29.17

Gene sequence:

>600_bases
ATGAGCAAATTATATTTTAGATACGGAGCTATGAATTCAGGTAAATCTACACACCTTATGCAAGTAGCACATAACTATGA
GGAAAGAGGTATGGAAGTTATAATAATTAAACCATCTACTGATAAAAAAGGTGGAGATAAGGTTGTTTCAAGACTAGGCG
TTGAGAGAGTTGTAGATATTTTAATAGATAATGATGAGAATATTATAGAAACAATTGAAGATAGACTTGAAAAAGGAAGA
AAAATAGATTGTATAATAGTTGATGAAGTTCAATTTTTAAAAGCTCATCACATAGATGAATTATTTGAAATTGCAGTTGG
TAAGGGAATACCAGTAATTTGTTACGGATTAAGAACAGATTTCCAAATGAATGGGTTTGAAGGAAGTGAAAGACTTTTAT
TATTAGCACATAGTATAGAAGAAATGAAAACTATATGTAGATGTGGAAGAAAAGCTATATTAAATGGAAGAATGATAAAT
GGAAAGTTCACATTTGAAGGAGAACAAGTGGCTATAGATTTAGTTGATAATGTAGAATATCAATCTCTATGTGGACAATG
CTATTTTAAATATAAATATGGTAAGGATTCTGATAATTAG

Upstream 100 bases:

>100_bases
TATCATGGGGATATTTAATCGTCAATAGTTTAAAAGCTTTCTTATTTAAGTTATAATCATATTTAGAATATTATAAAAGG
ATAAGGAGTTTAAAGTTAAA

Downstream 100 bases:

>100_bases
TTAATGAAAGGATAGGGTTCAAATTATGAGAAAATGCCAAGTAAGGCGGTCAAGCAGTATTAGGAAGGCGTTATGATGAG
GGGATCAAAAGGAAACAGCT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSKLYFRYGAMNSGKSTHLMQVAHNYEERGMEVIIIKPSTDKKGGDKVVSRLGVERVVDILIDNDENIIETIEDRLEKGR
KIDCIIVDEVQFLKAHHIDELFEIAVGKGIPVICYGLRTDFQMNGFEGSERLLLLAHSIEEMKTICRCGRKAILNGRMIN
GKFTFEGEQVAIDLVDNVEYQSLCGQCYFKYKYGKDSDN

Sequences:

>Translated_199_residues
MSKLYFRYGAMNSGKSTHLMQVAHNYEERGMEVIIIKPSTDKKGGDKVVSRLGVERVVDILIDNDENIIETIEDRLEKGR
KIDCIIVDEVQFLKAHHIDELFEIAVGKGIPVICYGLRTDFQMNGFEGSERLLLLAHSIEEMKTICRCGRKAILNGRMIN
GKFTFEGEQVAIDLVDNVEYQSLCGQCYFKYKYGKDSDN
>Mature_198_residues
SKLYFRYGAMNSGKSTHLMQVAHNYEERGMEVIIIKPSTDKKGGDKVVSRLGVERVVDILIDNDENIIETIEDRLEKGRK
IDCIIVDEVQFLKAHHIDELFEIAVGKGIPVICYGLRTDFQMNGFEGSERLLLLAHSIEEMKTICRCGRKAILNGRMING
KFTFEGEQVAIDLVDNVEYQSLCGQCYFKYKYGKDSDN

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=42.1052631578947, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22681; Mature: 22550

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLYFRYGAMNSGKSTHLMQVAHNYEERGMEVIIIKPSTDKKGGDKVVSRLGVERVVDI
CCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LIDNDENIIETIEDRLEKGRKIDCIIVDEVQFLKAHHIDELFEIAVGKGIPVICYGLRTD
HCCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
FQMNGFEGSERLLLLAHSIEEMKTICRCGRKAILNGRMINGKFTFEGEQVAIDLVDNVEY
EEECCCCCCCEEEEEHHHHHHHHHHHHCCHHHHHCCEEECCEEEECCCEEEEEEECCCCH
QSLCGQCYFKYKYGKDSDN
HHHHHHEEEEEECCCCCCC
>Mature Secondary Structure 
SKLYFRYGAMNSGKSTHLMQVAHNYEERGMEVIIIKPSTDKKGGDKVVSRLGVERVVDI
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LIDNDENIIETIEDRLEKGRKIDCIIVDEVQFLKAHHIDELFEIAVGKGIPVICYGLRTD
HCCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
FQMNGFEGSERLLLLAHSIEEMKTICRCGRKAILNGRMINGKFTFEGEQVAIDLVDNVEY
EEECCCCCCCEEEEEHHHHHHHHHHHHCCHHHHHCCEEECCEEEECCCEEEEEEECCCCH
QSLCGQCYFKYKYGKDSDN
HHHHHHEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]