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The map label for this gene is fur1 [H]

Identifier: 17547466

GI number: 17547466

Start: 2957842

End: 2958273

Strand: Direct

Name: fur1 [H]

Synonym: RSc2747

Alternate gene names: 17547466

Gene position: 2957842-2958273 (Clockwise)

Preceding gene: 17547457

Following gene: 17547480

Centisome position: 79.59

GC content: 61.57

Gene sequence:

>432_bases
ATGCCGAGTCCTGCAGACCTCAAGAACATCGGTCTGAAAGCCACGGTGCCGCGGTTGAAGATTCTCGAAATCTTCCAGAC
CAGCGAAGAGCGTCACATGAGCGCCGAAGACGTGTACCGCATCCTGCTCGCCGAGCACATGGATATCGGGCTGGCAACGG
TCTACCGCGTGCTGACCCAGTTCGAGCAGGCCGGCCTGCTGTCACGCAACAATTTCGAGTCCGGCAAGGCCATCTACGAG
CTCAACGAAGGCAAGCACCATGATCACCTGGTCTGCCTCGATTGCGGCCGCGTGGAGGAATTCTTCGACGGCGAGATCGA
GCAGCGCCAGCAGAGCATCGCCCGCGCCCGCGGATTCGCGCTGCAGGAGCATGCCTTGTCGCTGTACGGCAATTGCACCA
AGGAACCCTGCCCGCACCGGCCCAAGCGCTGA

Upstream 100 bases:

>100_bases
GGCGACACTGGCGCGTCAAGCGCGCCCGTCGATAGGACTTTTGCCGCCAAAACCCTTATGATTGGAATATCTGAACATTG
TACTCTAGGGAGCTAGGCGC

Downstream 100 bases:

>100_bases
CGCAACAGCCGCCTCATCAAAAAAAACGGCCGCATCCACTGCGGCCGTTTTCGTTGGAGGAGCGCGGTGCTGGCATCAGA
CGGACAGCCGCGACTCATCC

Product: ferric uptake transcriptional repressor transcription regulator protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MPSPADLKNIGLKATVPRLKILEIFQTSEERHMSAEDVYRILLAEHMDIGLATVYRVLTQFEQAGLLSRNNFESGKAIYE
LNEGKHHDHLVCLDCGRVEEFFDGEIEQRQQSIARARGFALQEHALSLYGNCTKEPCPHRPKR

Sequences:

>Translated_143_residues
MPSPADLKNIGLKATVPRLKILEIFQTSEERHMSAEDVYRILLAEHMDIGLATVYRVLTQFEQAGLLSRNNFESGKAIYE
LNEGKHHDHLVCLDCGRVEEFFDGEIEQRQQSIARARGFALQEHALSLYGNCTKEPCPHRPKR
>Mature_142_residues
PSPADLKNIGLKATVPRLKILEIFQTSEERHMSAEDVYRILLAEHMDIGLATVYRVLTQFEQAGLLSRNNFESGKAIYEL
NEGKHHDHLVCLDCGRVEEFFDGEIEQRQQSIARARGFALQEHALSLYGNCTKEPCPHRPKR

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=131, Percent_Identity=54.9618320610687, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16334; Mature: 16203

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPADLKNIGLKATVPRLKILEIFQTSEERHMSAEDVYRILLAEHMDIGLATVYRVLTQ
CCCCCCHHHCCCCCCCCHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
FEQAGLLSRNNFESGKAIYELNEGKHHDHLVCLDCGRVEEFFDGEIEQRQQSIARARGFA
HHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHCCH
LQEHALSLYGNCTKEPCPHRPKR
HHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSPADLKNIGLKATVPRLKILEIFQTSEERHMSAEDVYRILLAEHMDIGLATVYRVLTQ
CCCCCHHHCCCCCCCCHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
FEQAGLLSRNNFESGKAIYELNEGKHHDHLVCLDCGRVEEFFDGEIEQRQQSIARARGFA
HHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHCCH
LQEHALSLYGNCTKEPCPHRPKR
HHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA