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The map label for this gene is xseB

Identifier: 17546942

GI number: 17546942

Start: 2411381

End: 2411665

Strand: Reverse

Name: xseB

Synonym: RSc2223

Alternate gene names: 17546942

Gene position: 2411665-2411381 (Counterclockwise)

Preceding gene: 17546946

Following gene: 17546941

Centisome position: 64.89

GC content: 66.32

Gene sequence:

>285_bases
ATGCCCCGTGCCCAAGACGTCGCCCAGAGCGATGCAACCCTTTCCTCTCCAGCGACCCCAGCTTCCTATGAGGCGGCCAT
GGCTGAACTCGAAACCCTCGTCGCCAGCATGGAGTCCGGTGAATTGCCGCTGGAAGCCTCGCTGGCGGCATATCGCCGCG
GCGCCGAGCTGGTCAGGTATTGCCAGCAGGTGCTGGAGCGCGTCGAGCAGCAGGTGCGCGTGCTCGACGGCGATGCCCTG
AAGCCCCTGGCGGGCGAAGGCACGAACGAACAGGGCGGAGCATGA

Upstream 100 bases:

>100_bases
GCGTGACGTGAGCGCTCGCCGAGCGTGACGCGGCCGGCACGCGGAGCCCGCGTGGAATTGCCGTAAAATGCGGGACTGTT
CTTTCCTTTCCGCAACCGGC

Downstream 100 bases:

>100_bases
GCGATTTCGCCCACTGGATGGCCTCCGTCGTTGCACGGACGGAAAGCGCGCTCGAACGCGCCCTGCCCGGCGAATCGGTC
GCGCCGCAGCGCCTGCATGC

Product: exodeoxyribonuclease VII small subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII small subunit; Exonuclease VII small subunit

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MPRAQDVAQSDATLSSPATPASYEAAMAELETLVASMESGELPLEASLAAYRRGAELVRYCQQVLERVEQQVRVLDGDAL
KPLAGEGTNEQGGA

Sequences:

>Translated_94_residues
MPRAQDVAQSDATLSSPATPASYEAAMAELETLVASMESGELPLEASLAAYRRGAELVRYCQQVLERVEQQVRVLDGDAL
KPLAGEGTNEQGGA
>Mature_93_residues
PRAQDVAQSDATLSSPATPASYEAAMAELETLVASMESGELPLEASLAAYRRGAELVRYCQQVLERVEQQVRVLDGDALK
PLAGEGTNEQGGA

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1722

COG function: function code L; Exonuclease VII small subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseB family

Homologues:

Organism=Escherichia coli, GI1786624, Length=59, Percent_Identity=47.4576271186441, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7S_RALSO (Q8XX93)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520344.1
- ProteinModelPortal:   Q8XX93
- SMR:   Q8XX93
- GeneID:   1221068
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2223
- NMPDR:   fig|267608.1.peg.2223
- HOGENOM:   HBG728416
- OMA:   AEPASYE
- ProtClustDB:   PRK00977
- BioCyc:   RSOL267608:RSC2223-MONOMER
- BRENDA:   3.1.11.6
- GO:   GO:0005737
- HAMAP:   MF_00337
- InterPro:   IPR003761
- PIRSF:   PIRSF006488
- ProDom:   PD028235
- TIGRFAMs:   TIGR01280

Pfam domain/function: PF02609 Exonuc_VII_S

EC number: =3.1.11.6

Molecular weight: Translated: 9936; Mature: 9805

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRAQDVAQSDATLSSPATPASYEAAMAELETLVASMESGELPLEASLAAYRRGAELVRY
CCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHH
CQQVLERVEQQVRVLDGDALKPLAGEGTNEQGGA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRAQDVAQSDATLSSPATPASYEAAMAELETLVASMESGELPLEASLAAYRRGAELVRY
CCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHH
CQQVLERVEQQVRVLDGDALKPLAGEGTNEQGGA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852