Click here to switch to the map view.

The map label for this gene is zupT [H]

Identifier: 17546946

GI number: 17546946

Start: 2415164

End: 2415970

Strand: Reverse

Name: zupT [H]

Synonym: RSc2227

Alternate gene names: 17546946

Gene position: 2415970-2415164 (Counterclockwise)

Preceding gene: 17546947

Following gene: 17546942

Centisome position: 65.01

GC content: 66.17

Gene sequence:

>807_bases
ATGACCGCTGATTCCACCCTGTTAGGCATTCTTCTCGCTACCGCGCTGTCCGGCATCGGCAGCATGGCCGGCGCCGCCGC
GCTGTCGCTGACCGTGCTGGCGCGCGTGGTTGACCGCATGGTCAGTTTCTCTGTCGGCGTGCTGCTGGCGACGTCGCTGC
TGCACTCGCTGCCCGAGGCGTTCGAGTCGCACCACGGCATCGAGCCCAATACCCACGCCCTGTTCGCCACGCTGCTGGCG
GGGCTGCTGGGGTTCTTCCTGCTGGAGAAGATTGCGCTGATCCGCCATTCGCACCATCACGAGGGCGACGGCCATGGCCA
CCACCACGGCCATGACCGGCAGGAGGCGGGCCGCAGCGGGCTGATGATCCTGGTGGGCGACGGCCTGCACAACTTCTCCG
ATGGCATCGTCATCGCCGCGGCCTTCCTGGCCGACACGCGTGTCGGCATCGTCACCGCGCTGGCGATCGCGGCGCACGAG
ATCCCGCAGGAGATCGGCGATTTCATGGTGCTGCTCAACGCCGGCTTCTCCAAGACGCGCGCCTTCGTCTACAACCTGAT
CTGCAGCGTGTGCGCGCTGGTGGGGGCGGTGCTCGGCTATTACCTGCTGGATCGCATGTCGGCGTGGATTCCCTACGTGC
TGGTGGTGGCCTCCAGCAGCTTCATCTACATCGCCGTGTGCGATCTGATGCCGCAGATGAAGCGCCGGCCGCGCTGGCAG
GAGTCCGCCGTGCAGATCGCGCTGGTCACGGCGGGCATCGTGATGATCTTTCTGCTGACCGACGGTCTGCACCACCACGC
GCATTGA

Upstream 100 bases:

>100_bases
CGCGGGCCTTTTGTTTTGCGGCGATGCTGGCAAAGGTCGGCAAAGGCGCATACAATGCCTTTCTTCTTGCAACTCTGTTG
CGTTTGTTGGCGACCGCCGC

Downstream 100 bases:

>100_bases
TGGTCCGGTGAGCGGAACCGCATGAAAAAAAGCCCGGCATTGCCGGGCTTTTTGCTGGTCGCGCCGGGGCCCGGCGTCAT
GGATTCGGTCCGGTCGCCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTADSTLLGILLATALSGIGSMAGAAALSLTVLARVVDRMVSFSVGVLLATSLLHSLPEAFESHHGIEPNTHALFATLLA
GLLGFFLLEKIALIRHSHHHEGDGHGHHHGHDRQEAGRSGLMILVGDGLHNFSDGIVIAAAFLADTRVGIVTALAIAAHE
IPQEIGDFMVLLNAGFSKTRAFVYNLICSVCALVGAVLGYYLLDRMSAWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQ
ESAVQIALVTAGIVMIFLLTDGLHHHAH

Sequences:

>Translated_268_residues
MTADSTLLGILLATALSGIGSMAGAAALSLTVLARVVDRMVSFSVGVLLATSLLHSLPEAFESHHGIEPNTHALFATLLA
GLLGFFLLEKIALIRHSHHHEGDGHGHHHGHDRQEAGRSGLMILVGDGLHNFSDGIVIAAAFLADTRVGIVTALAIAAHE
IPQEIGDFMVLLNAGFSKTRAFVYNLICSVCALVGAVLGYYLLDRMSAWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQ
ESAVQIALVTAGIVMIFLLTDGLHHHAH
>Mature_267_residues
TADSTLLGILLATALSGIGSMAGAAALSLTVLARVVDRMVSFSVGVLLATSLLHSLPEAFESHHGIEPNTHALFATLLAG
LLGFFLLEKIALIRHSHHHEGDGHGHHHGHDRQEAGRSGLMILVGDGLHNFSDGIVIAAAFLADTRVGIVTALAIAAHEI
PQEIGDFMVLLNAGFSKTRAFVYNLICSVCALVGAVLGYYLLDRMSAWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQE
SAVQIALVTAGIVMIFLLTDGLHHHAH

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI187936949, Length=128, Percent_Identity=39.84375, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI55741750, Length=128, Percent_Identity=39.84375, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI223633937, Length=258, Percent_Identity=32.9457364341085, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI40255101, Length=263, Percent_Identity=29.277566539924, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI223633939, Length=295, Percent_Identity=30.1694915254237, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI190014617, Length=270, Percent_Identity=28.5185185185185, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI153252201, Length=131, Percent_Identity=36.6412213740458, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI190358541, Length=127, Percent_Identity=36.2204724409449, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI205830424, Length=127, Percent_Identity=36.2204724409449, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI190360568, Length=127, Percent_Identity=36.2204724409449, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI153252214, Length=128, Percent_Identity=35.9375, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI205830426, Length=116, Percent_Identity=37.9310344827586, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI115430255, Length=121, Percent_Identity=41.3223140495868, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI115430259, Length=121, Percent_Identity=41.3223140495868, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI205830407, Length=161, Percent_Identity=31.055900621118, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI24586665, Length=161, Percent_Identity=31.055900621118, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI205830403, Length=161, Percent_Identity=31.055900621118, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI205830405, Length=130, Percent_Identity=33.8461538461538, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI206597541, Length=139, Percent_Identity=39.568345323741, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI206597539, Length=139, Percent_Identity=39.568345323741, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI117553619, Length=150, Percent_Identity=31.3333333333333, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI117553608, Length=150, Percent_Identity=31.3333333333333, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193209531, Length=226, Percent_Identity=29.2035398230088, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71992548, Length=140, Percent_Identity=34.2857142857143, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71998183, Length=142, Percent_Identity=35.9154929577465, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994730, Length=277, Percent_Identity=25.6317689530686, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17538884, Length=109, Percent_Identity=34.8623853211009, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566718, Length=121, Percent_Identity=24.7933884297521, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32566720, Length=121, Percent_Identity=24.7933884297521, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322166, Length=247, Percent_Identity=27.1255060728745, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161083817, Length=154, Percent_Identity=37.012987012987, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24664383, Length=154, Percent_Identity=37.012987012987, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45549201, Length=114, Percent_Identity=42.1052631578947, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24651189, Length=278, Percent_Identity=26.2589928057554, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24651193, Length=278, Percent_Identity=26.2589928057554, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24651187, Length=278, Percent_Identity=26.2589928057554, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24651191, Length=278, Percent_Identity=26.2589928057554, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24651195, Length=278, Percent_Identity=26.2589928057554, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24651197, Length=278, Percent_Identity=26.2589928057554, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17864610, Length=142, Percent_Identity=33.0985915492958, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28677; Mature: 28546

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADSTLLGILLATALSGIGSMAGAAALSLTVLARVVDRMVSFSVGVLLATSLLHSLPEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FESHHGIEPNTHALFATLLAGLLGFFLLEKIALIRHSHHHEGDGHGHHHGHDRQEAGRSG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCC
LMILVGDGLHNFSDGIVIAAAFLADTRVGIVTALAIAAHEIPQEIGDFMVLLNAGFSKTR
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AFVYNLICSVCALVGAVLGYYLLDRMSAWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
ESAVQIALVTAGIVMIFLLTDGLHHHAH
HHHHHHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
TADSTLLGILLATALSGIGSMAGAAALSLTVLARVVDRMVSFSVGVLLATSLLHSLPEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FESHHGIEPNTHALFATLLAGLLGFFLLEKIALIRHSHHHEGDGHGHHHGHDRQEAGRSG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCC
LMILVGDGLHNFSDGIVIAAAFLADTRVGIVTALAIAAHEIPQEIGDFMVLLNAGFSKTR
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AFVYNLICSVCALVGAVLGYYLLDRMSAWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
ESAVQIALVTAGIVMIFLLTDGLHHHAH
HHHHHHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA