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The map label for this gene is ihfA

Identifier: 17546302

GI number: 17546302

Start: 1699590

End: 1699904

Strand: Direct

Name: ihfA

Synonym: RSc1583

Alternate gene names: 17546302

Gene position: 1699590-1699904 (Clockwise)

Preceding gene: 17546301

Following gene: 17546303

Centisome position: 45.73

GC content: 64.76

Gene sequence:

>315_bases
GTGCCGACGCTGACCAAGGCCGAGCTCGCCGAGATGCTGTTCGAGCAGGTCGGCCTGAACAAGCGTGAGTCGAAGGACAT
GGTCGAAGCTTTTTTCGACGTGATTCGCGAGGCGCTCGAACAGGGCGACAGCGTCAAGCTGTCCGGCTTCGGCAACTTCC
AGCTGCGCGACAAGCCGCAGCGTCCGGGGCGCAATCCGAAGACCGGCGAGATCATTCCCATCACGGCGCGCCGTGTCGTC
ACCTTCCACGCGAGCCAGAAGCTCAAGGCGCTCGTCGAGGAGCGCGTCGAGCCGATGCCCGCCAGCGCTGCGTAA

Upstream 100 bases:

>100_bases
CGATCAACACGCATCCTCGCTGGCGGCTTCGCTGGGCGACGCGCTCGGTTCTTCCTCGGCGGCCCTGGCCGATGCGCGCG
ATGCCGCGCGCGGCCAGGAC

Downstream 100 bases:

>100_bases
TTTCGCGTCTTCGCTTGCGCCACCATGGTCGCCGATAAACACACGGAGCGGATCAATCTGCCGCCGATTCCTGCCAAGCG
CTACTTCACCATCGGTGAGG

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MPTLTKAELAEMLFEQVGLNKRESKDMVEAFFDVIREALEQGDSVKLSGFGNFQLRDKPQRPGRNPKTGEIIPITARRVV
TFHASQKLKALVEERVEPMPASAA

Sequences:

>Translated_104_residues
MPTLTKAELAEMLFEQVGLNKRESKDMVEAFFDVIREALEQGDSVKLSGFGNFQLRDKPQRPGRNPKTGEIIPITARRVV
TFHASQKLKALVEERVEPMPASAA
>Mature_103_residues
PTLTKAELAEMLFEQVGLNKRESKDMVEAFFDVIREALEQGDSVKLSGFGNFQLRDKPQRPGRNPKTGEIIPITARRVVT
FHASQKLKALVEERVEPMPASAA

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=90, Percent_Identity=71.1111111111111, Blast_Score=132, Evalue=4e-33,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=36.6666666666667, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_RALSO (Q8XZ23)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519704.1
- ProteinModelPortal:   Q8XZ23
- SMR:   Q8XZ23
- GeneID:   1220415
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1583
- NMPDR:   fig|267608.1.peg.1583
- HOGENOM:   HBG705085
- OMA:   VRGETVK
- ProtClustDB:   PRK00285
- BioCyc:   RSOL267608:RSC1583-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11640; Mature: 11508

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLTKAELAEMLFEQVGLNKRESKDMVEAFFDVIREALEQGDSVKLSGFGNFQLRDKPQ
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
RPGRNPKTGEIIPITARRVVTFHASQKLKALVEERVEPMPASAA
CCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PTLTKAELAEMLFEQVGLNKRESKDMVEAFFDVIREALEQGDSVKLSGFGNFQLRDKPQ
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
RPGRNPKTGEIIPITARRVVTFHASQKLKALVEERVEPMPASAA
CCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852