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The map label for this gene is pheT

Identifier: 17546301

GI number: 17546301

Start: 1696988

End: 1699417

Strand: Direct

Name: pheT

Synonym: RSc1582

Alternate gene names: 17546301

Gene position: 1696988-1699417 (Clockwise)

Preceding gene: 17546300

Following gene: 17546302

Centisome position: 45.66

GC content: 67.0

Gene sequence:

>2430_bases
ATGCAATTTCCGGAATCCTGGCTTCGCAGTTTCGTCAATCCGCCGATCGCCACCGCTGAGCTCTCCCATCGCCTGACGAT
GGCCGGTCTCGAGGTGGAAGAGGTCGATCCCGTCGCGCCACCGTTCTCGCAGATCGTTGTCGGCCACGTGGTCGAGGTGA
ACAAGCACCCGGACGCCGATCGCCTGAACGTCTGCAAGGTGGATGCCGGCACGGGCGAGCTGCTGCAGATCGTCTGCGGC
GCCCCGAATGTGTCGGTGGGCATCAAGGTGCCGTGCGCATTGGTGGGCGCCGAGCTGCCGCCGGGCGACGACGGCAAGCC
GTTCAAGATCAAGATCGGCAAGCTGCGCGGTGTGGAGAGCTACGGCATGCTGTGCTCGGCGCGCGAGCTGAAGCTGTCGG
AAGAGCACGGCGGCCTGCTGATCCTGCCGGAAGACACGCCGGTGGGCGCGGACATCCGCAAGGTGCTGGACCTGGACGAC
CAGATCTTCATCATCAAGCTCACGCCCAACAAGGCGGACTGCCTGTCGATCCACGGCGTGGCGCGCGAGGTGTCCGCGCT
GACGGGCGCGCCGATCACGCTGCCGACGATGGCGCCGGTGGCAGTGACGCTCTCCGACAAGCTGCCGGTCAAGGTGGAGG
CGCCGGACCTGTGCGGCCGCTTTGCGGGTCGCATCATCCGCGGCGTCAATGCGCGTGCGAAGACGCCGGCATGGATGGTG
TCGCGCATCGAGCGCGCGGGCATGCGCAGCGTGTCGGCGCTGGTCGATATCTCCAACTATGTGATGCTGGAACTGGGCCG
TCCGTCGCACGTGTTCGACCTGGACAAGATCCATGGCGGCCTGACGGTGCGCTGGGGCAAGCCCGGTGAGCAGCTGAAGC
TGCTGAACGGCGACACCGTCACCGTCGATGACAAGGTCGGCGTGATCTCGGACGAGCAGGCCATCGAAAGCTTGGCCGGC
ATCATGGGCGGCGACAAGACCGCCGTCACGCTCGACACGCAAAACATCTACGTCGAGGCCGCGTTCTGGTGGCCCGCCGC
CATCCAGGGGCGCGCGCGCCGCTACAACTTCTCGACCGACGCCGGCCACCGCTTCGAGCGCGGCGTCGACTATGCGACCA
TCGTCGAACACATCGAGCGCATCAGCGCGTTGATCCTCGATATCTGCGGCGGCCAGGCCGGCCCGATCGACGATCAGATC
GTCAATTGCCCCAAGCGCGAGCCGGTGCGCATGCGCGTGGCGCGTGCCGCGCGTGTGCTCGGTATTCCGCTGTCGCACGA
AGTCGTGTCGGATGTGTTCAAGCGCCTCGGTCTCACGTTCAGCGTGGACGGCGATGTGTTCGTGGTCGAGCCGCCGTCGT
ACCGTTTCGACATCGAGATCGAGGAAGACCTGATCGAAGAGGTCGCCCGCATCTACGGTTTCGAGCAGATCCCGGCCAAG
CCGCCGGTTGCTGAAAACGCCATGCGCCCGACCAACGAGGCACGCCGCACGATGCACGACGTGCGTCACGCCGTGGCCGC
GCGCGATTACCACGAGGTCGTGAACTTCGCCTTCGTCGAGACCGAATGGGAAGCCGACTTTGCCGGCAACACGCAGCCGA
TCCCGTTGCTGAACCCGATCGCCAGCCAGTATTCGGTGATGCGCAGCACGCTGATCGGCGGCTTGCTCGACAAGGTGCGC
TATAACCTGAACCGCAAGGCTTCGCGCGTGCGCCTGTTCGAGGTGGGCCGCGTGTTCCGCCGCGATGCGGAGGTGGCCGA
CGGCGGCCTGTCCGTGGCCGGCTATGCGCAGCCGATGCGGGTGGGCGGCATTGCCTACGGCCCGGCCGCGGAGGAGCAGT
GGGGCGTGCCGGCGCGCGCTGTCGATTTCTTCGATGTGAAGGGCGATGTCGAGTCGCTGCTGTGGCCGCTGCAGGCGCGC
TTCGAGCGTGCCGAGCATTCGGCGCTGCATCCGGGCCGCGCTGCCCGCGTGGTGCTGGACGGCCGCGCCGTCGGCTGGAT
CGGTGAGCTGCATCCGCGCTGGCTGCAGAAGTACGAGCTGCCCACCGCGCCGGTGGTGTGGGAGCTGGACCTGGACGCCA
TCACTGCCGTCGGGCTGCCGGCCTATCGCGAAGTGCCGCGCGTGCCGGCGGTGACGCGCGACATCGCGCTGGTCGTGCGT
CAGGACGTGGGCGTGCAGGACCTCGTCGATGCGTTCGAGAAGGCGGCGGCCGGCATGCCGTGGCAGCGTTACCTGCAGGG
CGTCGTGCTGTTCGACGAGTTCCGTCCGAAGGCCGCGACGGCCGCGATCGGGGCGCAGGAGAAAAGCCTTGCCTTCAGGA
TTACGTTGCAAGATACTGACAGCACCCTTCAGGACGATCTCGTCGAGGCCGCCACGCAGCAGCTGATTCGTGCGGCCGGC
GATGCATTCGGTGCGCGTCTGCGTGCCTGA

Upstream 100 bases:

>100_bases
GGGCGACGTGCGCTTCCTGCGCCAGTTCGCGTAACGCGGACGCCTGCCGTCCGCGGGTTCGCCGTTTCCCTGTTCACCGA
ATTCCTTTTTCTGTCGCGCC

Downstream 100 bases:

>100_bases
CGTCCGCGCCGCGCTCAGACCGCTCGAACGAACCTCCGCATTCGGATCGACCACGCAAGCGAATCCTATGAACGATCAAC
ACGCATCCTCGCTGGCGGCT

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS

Number of amino acids: Translated: 809; Mature: 809

Protein sequence:

>809_residues
MQFPESWLRSFVNPPIATAELSHRLTMAGLEVEEVDPVAPPFSQIVVGHVVEVNKHPDADRLNVCKVDAGTGELLQIVCG
APNVSVGIKVPCALVGAELPPGDDGKPFKIKIGKLRGVESYGMLCSARELKLSEEHGGLLILPEDTPVGADIRKVLDLDD
QIFIIKLTPNKADCLSIHGVAREVSALTGAPITLPTMAPVAVTLSDKLPVKVEAPDLCGRFAGRIIRGVNARAKTPAWMV
SRIERAGMRSVSALVDISNYVMLELGRPSHVFDLDKIHGGLTVRWGKPGEQLKLLNGDTVTVDDKVGVISDEQAIESLAG
IMGGDKTAVTLDTQNIYVEAAFWWPAAIQGRARRYNFSTDAGHRFERGVDYATIVEHIERISALILDICGGQAGPIDDQI
VNCPKREPVRMRVARAARVLGIPLSHEVVSDVFKRLGLTFSVDGDVFVVEPPSYRFDIEIEEDLIEEVARIYGFEQIPAK
PPVAENAMRPTNEARRTMHDVRHAVAARDYHEVVNFAFVETEWEADFAGNTQPIPLLNPIASQYSVMRSTLIGGLLDKVR
YNLNRKASRVRLFEVGRVFRRDAEVADGGLSVAGYAQPMRVGGIAYGPAAEEQWGVPARAVDFFDVKGDVESLLWPLQAR
FERAEHSALHPGRAARVVLDGRAVGWIGELHPRWLQKYELPTAPVVWELDLDAITAVGLPAYREVPRVPAVTRDIALVVR
QDVGVQDLVDAFEKAAAGMPWQRYLQGVVLFDEFRPKAATAAIGAQEKSLAFRITLQDTDSTLQDDLVEAATQQLIRAAG
DAFGARLRA

Sequences:

>Translated_809_residues
MQFPESWLRSFVNPPIATAELSHRLTMAGLEVEEVDPVAPPFSQIVVGHVVEVNKHPDADRLNVCKVDAGTGELLQIVCG
APNVSVGIKVPCALVGAELPPGDDGKPFKIKIGKLRGVESYGMLCSARELKLSEEHGGLLILPEDTPVGADIRKVLDLDD
QIFIIKLTPNKADCLSIHGVAREVSALTGAPITLPTMAPVAVTLSDKLPVKVEAPDLCGRFAGRIIRGVNARAKTPAWMV
SRIERAGMRSVSALVDISNYVMLELGRPSHVFDLDKIHGGLTVRWGKPGEQLKLLNGDTVTVDDKVGVISDEQAIESLAG
IMGGDKTAVTLDTQNIYVEAAFWWPAAIQGRARRYNFSTDAGHRFERGVDYATIVEHIERISALILDICGGQAGPIDDQI
VNCPKREPVRMRVARAARVLGIPLSHEVVSDVFKRLGLTFSVDGDVFVVEPPSYRFDIEIEEDLIEEVARIYGFEQIPAK
PPVAENAMRPTNEARRTMHDVRHAVAARDYHEVVNFAFVETEWEADFAGNTQPIPLLNPIASQYSVMRSTLIGGLLDKVR
YNLNRKASRVRLFEVGRVFRRDAEVADGGLSVAGYAQPMRVGGIAYGPAAEEQWGVPARAVDFFDVKGDVESLLWPLQAR
FERAEHSALHPGRAARVVLDGRAVGWIGELHPRWLQKYELPTAPVVWELDLDAITAVGLPAYREVPRVPAVTRDIALVVR
QDVGVQDLVDAFEKAAAGMPWQRYLQGVVLFDEFRPKAATAAIGAQEKSLAFRITLQDTDSTLQDDLVEAATQQLIRAAG
DAFGARLRA
>Mature_809_residues
MQFPESWLRSFVNPPIATAELSHRLTMAGLEVEEVDPVAPPFSQIVVGHVVEVNKHPDADRLNVCKVDAGTGELLQIVCG
APNVSVGIKVPCALVGAELPPGDDGKPFKIKIGKLRGVESYGMLCSARELKLSEEHGGLLILPEDTPVGADIRKVLDLDD
QIFIIKLTPNKADCLSIHGVAREVSALTGAPITLPTMAPVAVTLSDKLPVKVEAPDLCGRFAGRIIRGVNARAKTPAWMV
SRIERAGMRSVSALVDISNYVMLELGRPSHVFDLDKIHGGLTVRWGKPGEQLKLLNGDTVTVDDKVGVISDEQAIESLAG
IMGGDKTAVTLDTQNIYVEAAFWWPAAIQGRARRYNFSTDAGHRFERGVDYATIVEHIERISALILDICGGQAGPIDDQI
VNCPKREPVRMRVARAARVLGIPLSHEVVSDVFKRLGLTFSVDGDVFVVEPPSYRFDIEIEEDLIEEVARIYGFEQIPAK
PPVAENAMRPTNEARRTMHDVRHAVAARDYHEVVNFAFVETEWEADFAGNTQPIPLLNPIASQYSVMRSTLIGGLLDKVR
YNLNRKASRVRLFEVGRVFRRDAEVADGGLSVAGYAQPMRVGGIAYGPAAEEQWGVPARAVDFFDVKGDVESLLWPLQAR
FERAEHSALHPGRAARVVLDGRAVGWIGELHPRWLQKYELPTAPVVWELDLDAITAVGLPAYREVPRVPAVTRDIALVVR
QDVGVQDLVDAFEKAAAGMPWQRYLQGVVLFDEFRPKAATAAIGAQEKSLAFRITLQDTDSTLQDDLVEAATQQLIRAAG
DAFGARLRA

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain

Homologues:

Organism=Homo sapiens, GI124028525, Length=405, Percent_Identity=23.9506172839506, Blast_Score=84, Evalue=5e-16,
Organism=Escherichia coli, GI1788006, Length=816, Percent_Identity=42.0343137254902, Blast_Score=615, Evalue=1e-177,
Organism=Drosophila melanogaster, GI21355211, Length=398, Percent_Identity=27.3869346733668, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFB_RALSO (Q8XZ24)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519703.1
- ProteinModelPortal:   Q8XZ24
- SMR:   Q8XZ24
- GeneID:   1220414
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1582
- NMPDR:   fig|267608.1.peg.1582
- HOGENOM:   HBG399638
- OMA:   ADKLRVC
- ProtClustDB:   PRK00629
- BioCyc:   RSOL267608:RSC1582-MONOMER
- BRENDA:   6.1.1.20
- GO:   GO:0005737
- HAMAP:   MF_00283
- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547
- Gene3D:   G3DSA:3.50.40.10
- Gene3D:   G3DSA:3.30.56.20
- Gene3D:   G3DSA:3.30.70.380
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00873
- SMART:   SM00874
- SMART:   SM00896
- TIGRFAMs:   TIGR00472

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind; SSF56037 B3_4; SSF54991 Fdx_AntiC_bd; SSF50249 Nucleic_acid_OB; SSF46955 Putativ_DNA_bind

EC number: =6.1.1.20

Molecular weight: Translated: 88487; Mature: 88487

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS51483 B5; PS51447 FDX_ACB; PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFPESWLRSFVNPPIATAELSHRLTMAGLEVEEVDPVAPPFSQIVVGHVVEVNKHPDAD
CCCHHHHHHHHCCCCCCHHHHHCEEEEECCCHHHCCCCCCCHHHHHHHHEEEECCCCCCC
RLNVCKVDAGTGELLQIVCGAPNVSVGIKVPCALVGAELPPGDDGKPFKIKIGKLRGVES
CCEEEEEECCCCHHHHEEECCCCCEEEEECCHHEECCCCCCCCCCCEEEEEEECCCCCHH
YGMLCSARELKLSEEHGGLLILPEDTPVGADIRKVLDLDDQIFIIKLTPNKADCLSIHGV
HCCEECCHHCEEECCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCEEEHHHH
AREVSALTGAPITLPTMAPVAVTLSDKLPVKVEAPDLCGRFAGRIIRGVNARAKTPAWMV
HHHHHHHCCCCEEECCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCHHHHH
SRIERAGMRSVSALVDISNYVMLELGRPSHVFDLDKIHGGLTVRWGKPGEQLKLLNGDTV
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEHHHCCCCEEEEECCCCCEEEEECCCEE
TVDDKVGVISDEQAIESLAGIMGGDKTAVTLDTQNIYVEAAFWWPAAIQGRARRYNFSTD
EECCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEEEEEECCHHHCCCCCEECCCCC
AGHRFERGVDYATIVEHIERISALILDICGGQAGPIDDQIVNCPKREPVRMRVARAARVL
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHH
GIPLSHEVVSDVFKRLGLTFSVDGDVFVVEPPSYRFDIEIEEDLIEEVARIYGFEQIPAK
CCCCCHHHHHHHHHHCCCEEEECCCEEEECCCCEEEEEEEHHHHHHHHHHHCCCHHCCCC
PPVAENAMRPTNEARRTMHDVRHAVAARDYHEVVNFAFVETEWEADFAGNTQPIPLLNPI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCHH
ASQYSVMRSTLIGGLLDKVRYNLNRKASRVRLFEVGRVFRRDAEVADGGLSVAGYAQPMR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCCCEECCCCCCCE
VGGIAYGPAAEEQWGVPARAVDFFDVKGDVESLLWPLQARFERAEHSALHPGRAARVVLD
ECCEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
GRAVGWIGELHPRWLQKYELPTAPVVWELDLDAITAVGLPAYREVPRVPAVTRDIALVVR
CCCEECHHHCCHHHHHHCCCCCCCEEEEECHHHHHHCCCCHHHHCCCCCCHHHHHHHHHH
QDVGVQDLVDAFEKAAAGMPWQRYLQGVVLFDEFRPKAATAAIGAQEKSLAFRITLQDTD
CCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEECCCCCHHHHHCCCCCCCEEEEEEEECCC
STLQDDLVEAATQQLIRAAGDAFGARLRA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQFPESWLRSFVNPPIATAELSHRLTMAGLEVEEVDPVAPPFSQIVVGHVVEVNKHPDAD
CCCHHHHHHHHCCCCCCHHHHHCEEEEECCCHHHCCCCCCCHHHHHHHHEEEECCCCCCC
RLNVCKVDAGTGELLQIVCGAPNVSVGIKVPCALVGAELPPGDDGKPFKIKIGKLRGVES
CCEEEEEECCCCHHHHEEECCCCCEEEEECCHHEECCCCCCCCCCCEEEEEEECCCCCHH
YGMLCSARELKLSEEHGGLLILPEDTPVGADIRKVLDLDDQIFIIKLTPNKADCLSIHGV
HCCEECCHHCEEECCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCEEEHHHH
AREVSALTGAPITLPTMAPVAVTLSDKLPVKVEAPDLCGRFAGRIIRGVNARAKTPAWMV
HHHHHHHCCCCEEECCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCHHHHH
SRIERAGMRSVSALVDISNYVMLELGRPSHVFDLDKIHGGLTVRWGKPGEQLKLLNGDTV
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEHHHCCCCEEEEECCCCCEEEEECCCEE
TVDDKVGVISDEQAIESLAGIMGGDKTAVTLDTQNIYVEAAFWWPAAIQGRARRYNFSTD
EECCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEEEEEECCHHHCCCCCEECCCCC
AGHRFERGVDYATIVEHIERISALILDICGGQAGPIDDQIVNCPKREPVRMRVARAARVL
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHH
GIPLSHEVVSDVFKRLGLTFSVDGDVFVVEPPSYRFDIEIEEDLIEEVARIYGFEQIPAK
CCCCCHHHHHHHHHHCCCEEEECCCEEEECCCCEEEEEEEHHHHHHHHHHHCCCHHCCCC
PPVAENAMRPTNEARRTMHDVRHAVAARDYHEVVNFAFVETEWEADFAGNTQPIPLLNPI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCHH
ASQYSVMRSTLIGGLLDKVRYNLNRKASRVRLFEVGRVFRRDAEVADGGLSVAGYAQPMR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCCCEECCCCCCCE
VGGIAYGPAAEEQWGVPARAVDFFDVKGDVESLLWPLQARFERAEHSALHPGRAARVVLD
ECCEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
GRAVGWIGELHPRWLQKYELPTAPVVWELDLDAITAVGLPAYREVPRVPAVTRDIALVVR
CCCEECHHHCCHHHHHHCCCCCCCEEEEECHHHHHHCCCCHHHHCCCCCCHHHHHHHHHH
QDVGVQDLVDAFEKAAAGMPWQRYLQGVVLFDEFRPKAATAAIGAQEKSLAFRITLQDTD
CCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEECCCCCHHHHHCCCCCCCEEEEEEEECCC
STLQDDLVEAATQQLIRAAGDAFGARLRA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852