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The map label for this gene is pncB [H]

Identifier: 17545750

GI number: 17545750

Start: 1083178

End: 1084392

Strand: Direct

Name: pncB [H]

Synonym: RSc1031

Alternate gene names: 17545750

Gene position: 1083178-1084392 (Clockwise)

Preceding gene: 17545745

Following gene: 17545751

Centisome position: 29.15

GC content: 64.69

Gene sequence:

>1215_bases
ATGACGACCATCCCGCGCGCAGGCGCCCCGCTTCCGGCCGTCCCGATGATCATCCGCTCGCTGCTCGACACCGATCTGTA
CAAGTTCACCATGATGCAGGTGGTGTTGCATCACTTTCCCGGTGCGCACGTCGAATACCGCTTCAAGTGCCGCAACCCGG
GCGTCGACCTGGTGCCGTACATCGAGGCGATCCGCGCGGAGATCCGCCACCTGTGCTCGCTGCGCTTCACCGAGGCGGAA
CTGGACTACCTGCGCGGGCTGCGCTTCATCAAGAGCGATTTCGTCGATTTTCTCGACCTGTTCCATCTCAGCGAGAAGTA
CATCGATATCCGCCCGGCGGCCTCCAACGACGGCCAGATCGACATCGTCATCAGCGGGCCGTGGCTGCACACCATCATGT
TCGAGGTGCCGGTGCTGGCCATCGTCAACGAGGTGTACTTCAGCCGCACCCAGGCCCACCCGCAGTGGGACGAGGGCAAG
CGCCGCCTGACCGAGAAGCTCGCCTCGCTCACGCGCCCGGGCCTGGAGGACTGCCGCATCGCCGATTACGGCACGCGCCG
CCGCTTCTCCCACACCTGGCACGAGCACGTGCTGATGGAGGCGCGCAGCCAGCTTGGCAGCCAGTACGCCGGCACCAGCA
ACGTCTACTTCGCCATGAAGCACAACATGACGCCGCTGGGCACCATGGCGCACGAGTACCTGCAGGCGTGCCAGTCGCTG
GGCCCGCGCCTGCGCGATTCACAGGTCTTCGCGCTGGAGACCTGGGCCCGGGAATACCGTGGCGACCTGGGCATCGCGTT
GTCCGACACCTACGGATTCGACGCCTTCCTGCGCGACTTCGACATGTTTTTCTGCAAGCTCTTCGATGGCGTGCGGCACG
ATTCCGGTGATCCGTTCGAGTGGGGCGAGCGCATGCTCAAGCACTACGAGGGCATGCGCGTCGACCCGCAATCCAAGGCG
CTGATCTTCTCCGACAGCCTGGACATGCCCAAGGTGGTGCGCCTGTACGAGCGCTTCCGCAGCCGCTGCAAGCTGGCCTT
CGGCGTCGGCACCAACCTGACCAACGACCTCGGCTACACGCCGCTGCAGATCGTCATCAAGATGGTCCGCTGCAACGGCC
AGCCGGTCGCCAAGCTGTCGGATGCGCCCGAGAAGACCATGTGCGACGACCCGGCCTACCTGGCCTACCTGAAGCAGGTG
TTCGGCGTGCAATGA

Upstream 100 bases:

>100_bases
GCGGAATCAAGGCCTTTTCCGGCCAGCAGGGCGGTCGAGGCCGGTGTTTTCACAGAGATTGACGGAAGTGGTCCCGACGG
CCCGCGAGGCTTCGGTTAGC

Downstream 100 bases:

>100_bases
GGCTCATGCGGGTGTCGAATACCTTTCAGCAGCCGGGCGCGCGATACCCGCGCGGCCGGCTCGTATAATCGACCGATTCC
ACGCAAGCCGCCCGGACATG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTTIPRAGAPLPAVPMIIRSLLDTDLYKFTMMQVVLHHFPGAHVEYRFKCRNPGVDLVPYIEAIRAEIRHLCSLRFTEAE
LDYLRGLRFIKSDFVDFLDLFHLSEKYIDIRPAASNDGQIDIVISGPWLHTIMFEVPVLAIVNEVYFSRTQAHPQWDEGK
RRLTEKLASLTRPGLEDCRIADYGTRRRFSHTWHEHVLMEARSQLGSQYAGTSNVYFAMKHNMTPLGTMAHEYLQACQSL
GPRLRDSQVFALETWAREYRGDLGIALSDTYGFDAFLRDFDMFFCKLFDGVRHDSGDPFEWGERMLKHYEGMRVDPQSKA
LIFSDSLDMPKVVRLYERFRSRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQPVAKLSDAPEKTMCDDPAYLAYLKQV
FGVQ

Sequences:

>Translated_404_residues
MTTIPRAGAPLPAVPMIIRSLLDTDLYKFTMMQVVLHHFPGAHVEYRFKCRNPGVDLVPYIEAIRAEIRHLCSLRFTEAE
LDYLRGLRFIKSDFVDFLDLFHLSEKYIDIRPAASNDGQIDIVISGPWLHTIMFEVPVLAIVNEVYFSRTQAHPQWDEGK
RRLTEKLASLTRPGLEDCRIADYGTRRRFSHTWHEHVLMEARSQLGSQYAGTSNVYFAMKHNMTPLGTMAHEYLQACQSL
GPRLRDSQVFALETWAREYRGDLGIALSDTYGFDAFLRDFDMFFCKLFDGVRHDSGDPFEWGERMLKHYEGMRVDPQSKA
LIFSDSLDMPKVVRLYERFRSRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQPVAKLSDAPEKTMCDDPAYLAYLKQV
FGVQ
>Mature_403_residues
TTIPRAGAPLPAVPMIIRSLLDTDLYKFTMMQVVLHHFPGAHVEYRFKCRNPGVDLVPYIEAIRAEIRHLCSLRFTEAEL
DYLRGLRFIKSDFVDFLDLFHLSEKYIDIRPAASNDGQIDIVISGPWLHTIMFEVPVLAIVNEVYFSRTQAHPQWDEGKR
RLTEKLASLTRPGLEDCRIADYGTRRRFSHTWHEHVLMEARSQLGSQYAGTSNVYFAMKHNMTPLGTMAHEYLQACQSLG
PRLRDSQVFALETWAREYRGDLGIALSDTYGFDAFLRDFDMFFCKLFDGVRHDSGDPFEWGERMLKHYEGMRVDPQSKAL
IFSDSLDMPKVVRLYERFRSRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQPVAKLSDAPEKTMCDDPAYLAYLKQVF
GVQ

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=393, Percent_Identity=43.765903307888, Blast_Score=324, Evalue=6e-90,
Organism=Saccharomyces cerevisiae, GI6324783, Length=416, Percent_Identity=30.2884615384615, Blast_Score=200, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 46461; Mature: 46330

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIPRAGAPLPAVPMIIRSLLDTDLYKFTMMQVVLHHFPGAHVEYRFKCRNPGVDLVPY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHH
IEAIRAEIRHLCSLRFTEAELDYLRGLRFIKSDFVDFLDLFHLSEKYIDIRPAASNDGQI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEE
DIVISGPWLHTIMFEVPVLAIVNEVYFSRTQAHPQWDEGKRRLTEKLASLTRPGLEDCRI
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEE
ADYGTRRRFSHTWHEHVLMEARSQLGSQYAGTSNVYFAMKHNMTPLGTMAHEYLQACQSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
GPRLRDSQVFALETWAREYRGDLGIALSDTYGFDAFLRDFDMFFCKLFDGVRHDSGDPFE
CCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
WGERMLKHYEGMRVDPQSKALIFSDSLDMPKVVRLYERFRSRCKLAFGVGTNLTNDLGYT
HHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCC
PLQIVIKMVRCNGQPVAKLSDAPEKTMCDDPAYLAYLKQVFGVQ
HHHHHHHHHHCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTIPRAGAPLPAVPMIIRSLLDTDLYKFTMMQVVLHHFPGAHVEYRFKCRNPGVDLVPY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHH
IEAIRAEIRHLCSLRFTEAELDYLRGLRFIKSDFVDFLDLFHLSEKYIDIRPAASNDGQI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEE
DIVISGPWLHTIMFEVPVLAIVNEVYFSRTQAHPQWDEGKRRLTEKLASLTRPGLEDCRI
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEE
ADYGTRRRFSHTWHEHVLMEARSQLGSQYAGTSNVYFAMKHNMTPLGTMAHEYLQACQSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
GPRLRDSQVFALETWAREYRGDLGIALSDTYGFDAFLRDFDMFFCKLFDGVRHDSGDPFE
CCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
WGERMLKHYEGMRVDPQSKALIFSDSLDMPKVVRLYERFRSRCKLAFGVGTNLTNDLGYT
HHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCC
PLQIVIKMVRCNGQPVAKLSDAPEKTMCDDPAYLAYLKQVFGVQ
HHHHHHHHHHCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA