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The map label for this gene is arsR [H]

Identifier: 17230258

GI number: 17230258

Start: 3362493

End: 3362819

Strand: Direct

Name: arsR [H]

Synonym: alr2766

Alternate gene names: 17230258

Gene position: 3362493-3362819 (Clockwise)

Preceding gene: 17230257

Following gene: 17230260

Centisome position: 52.43

GC content: 42.81

Gene sequence:

>327_bases
ATGCAAACCCCCACTGCTACCGTTCCTCATTTCATCGCTGCCGGTTTCCATGCTCTTTCTGATCCTATCAGGATTAATGT
CTTGGAATTACTTCGTCAGCGAGAATTGTGCGTCTGTGACTTGTGCGAAGCTTTGGGGGTAAGTCAATCAAAACTGTCTT
TTCACCTCAAAACTCTCAAAGAAGCTAGTTTAGTTAACTCCCGTCAACAAGGGCGCTGGATTTATTACAGTCTGAATTTG
CCTCAATTTGCTGTGTTAGAAAAGTATTTGACAGATTACCAACACTTTGGGCAAGTATTACCTGCACGCTGCTGTGATAA
TAAGTAG

Upstream 100 bases:

>100_bases
AAGCCTTAGACCGAATTAAGCAAGCTGGCATCCGTTATCGTCCAGAAGCTCTCGTTTCTGCCCCAGAATAGAGATAGCAG
CCCTTTATTGACTTTCATTC

Downstream 100 bases:

>100_bases
CCGATAATAGGTTAGGACTGACGCTGGGCAAGGGTATAGGGATTTATATAACTAAATTCCTTTGCAGTAGGGTGGGCATT
GCCCACCCTACTTATATTTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 108; Mature: 108

Protein sequence:

>108_residues
MQTPTATVPHFIAAGFHALSDPIRINVLELLRQRELCVCDLCEALGVSQSKLSFHLKTLKEASLVNSRQQGRWIYYSLNL
PQFAVLEKYLTDYQHFGQVLPARCCDNK

Sequences:

>Translated_108_residues
MQTPTATVPHFIAAGFHALSDPIRINVLELLRQRELCVCDLCEALGVSQSKLSFHLKTLKEASLVNSRQQGRWIYYSLNL
PQFAVLEKYLTDYQHFGQVLPARCCDNK
>Mature_108_residues
MQTPTATVPHFIAAGFHALSDPIRINVLELLRQRELCVCDLCEALGVSQSKLSFHLKTLKEASLVNSRQQGRWIYYSLNL
PQFAVLEKYLTDYQHFGQVLPARCCDNK

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=72, Percent_Identity=45.8333333333333, Blast_Score=64, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12308; Mature: 12308

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTPTATVPHFIAAGFHALSDPIRINVLELLRQRELCVCDLCEALGVSQSKLSFHLKTLK
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
EASLVNSRQQGRWIYYSLNLPQFAVLEKYLTDYQHFGQVLPARCCDNK
HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQTPTATVPHFIAAGFHALSDPIRINVLELLRQRELCVCDLCEALGVSQSKLSFHLKTLK
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
EASLVNSRQQGRWIYYSLNLPQFAVLEKYLTDYQHFGQVLPARCCDNK
HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8674982 [H]