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The map label for this gene is dapL [H]

Identifier: 17230257

GI number: 17230257

Start: 3361252

End: 3362463

Strand: Direct

Name: dapL [H]

Synonym: alr2765

Alternate gene names: 17230257

Gene position: 3361252-3362463 (Clockwise)

Preceding gene: 17230256

Following gene: 17230258

Centisome position: 52.41

GC content: 48.93

Gene sequence:

>1212_bases
ATGAGTTTCGATTGGATTACGCCAGCAGATAGGATACAGCAACTACCACCTTATGTATTTGCCCGTCTTGACGAGCTGAA
AGCTAAGGCAAGGGAGCAAGGAATTGATTTAATAGATTTGGGGATGGGGAATCCTGATGGCGCGACGCCACAACCAGTGG
TAGATGCGGCTATCCAAGCTTTGCAAGACCCCAAAAATCACGGTTACCCTCCCTTTGAAGGTACAGCAAGTTTCCGCCGT
GCCATTACTAACTGGTACAATCGCCGCTATGGGGTTGTACTAGACCCTGATAGTGAAGCCTTACCCCTACTCGGTTCTAA
AGAAGGATTATCTCATTTAGCGATCGCCTATGTGAACCCTGGCGATGTGGTGCTGGTTCCTTCTCCCGCCTACCCCGCCC
ATTTTCGTGGCCCGGTAATCGCTGGGGGTACAGTCCACAGCTTAATTCTTAAACCTGAGAATGACTGGTTAATTGATTTA
ACCGCCATTCCTGAAGAAGTTGCCAGAAAAGCCAAAATATTATACTTTAACTATCCCAGCAACCCCACAGGCGCAACTGC
ACCCCGTGAATTTTTCGAGGAAATTGTGGCATTTGCCCGCAAATACGAAATTCTCTTGGTGCATGATTTGTGTTATGCCG
AGTTAGCCTTTGATGGCTATCAACCCACCAGCTTACTAGAAATTCCTGGCGCAAAAGATATCGGCGTGGAGTTCCACACC
TTATCGAAAACCTACAATATGGCTGGTTGGCGTGTGGGCTTTGTTGTGGGGAATCGTCATGTAATTCAAGGCTTGCGGAC
ACTCAAAACCAACCTGGACTATGGCATTTTCGCCGCCTTGCAAACAGCCGCCGAAACAGCCTTACAACTACCAGATATTT
ATCTGCACGAAGTACAACAACGCTACCGCACCCGTCGGGATTTCCTCATCCAAGGATTAGGCGAGTTGGGCTGGGATGTT
CCCAAGACCAAAGCCACCATGTATCTGTGGGTGAAATGTCCTGTGGGTATGGGTTCAACGGATTTCGCCCTCAACTTGTT
GCAACAAACAGGCGTTGTCGTCACCCCTGGTAATGCCTTTGGGGTTGCCGGGGAGGGATATGTGCGGATAAGCTTAATTG
CAGATTGCGATCGTTTAGGTGAAGCCTTAGACCGAATTAAGCAAGCTGGCATCCGTTATCGTCCAGAAGCTCTCGTTTCT
GCCCCAGAATAG

Upstream 100 bases:

>100_bases
AACAGTTAATGGCAGCGATGGTTTCTACCACTGCACCAACAGATAGTAGAGACTCAGTTCATCGTGTCTCCACCAGGGGA
ATAAGTGACGAGGTTGAGGA

Downstream 100 bases:

>100_bases
AGATAGCAGCCCTTTATTGACTTTCATTCATGCAAACCCCCACTGCTACCGTTCCTCATTTCATCGCTGCCGGTTTCCAT
GCTCTTTCTGATCCTATCAG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSFDWITPADRIQQLPPYVFARLDELKAKAREQGIDLIDLGMGNPDGATPQPVVDAAIQALQDPKNHGYPPFEGTASFRR
AITNWYNRRYGVVLDPDSEALPLLGSKEGLSHLAIAYVNPGDVVLVPSPAYPAHFRGPVIAGGTVHSLILKPENDWLIDL
TAIPEEVARKAKILYFNYPSNPTGATAPREFFEEIVAFARKYEILLVHDLCYAELAFDGYQPTSLLEIPGAKDIGVEFHT
LSKTYNMAGWRVGFVVGNRHVIQGLRTLKTNLDYGIFAALQTAAETALQLPDIYLHEVQQRYRTRRDFLIQGLGELGWDV
PKTKATMYLWVKCPVGMGSTDFALNLLQQTGVVVTPGNAFGVAGEGYVRISLIADCDRLGEALDRIKQAGIRYRPEALVS
APE

Sequences:

>Translated_403_residues
MSFDWITPADRIQQLPPYVFARLDELKAKAREQGIDLIDLGMGNPDGATPQPVVDAAIQALQDPKNHGYPPFEGTASFRR
AITNWYNRRYGVVLDPDSEALPLLGSKEGLSHLAIAYVNPGDVVLVPSPAYPAHFRGPVIAGGTVHSLILKPENDWLIDL
TAIPEEVARKAKILYFNYPSNPTGATAPREFFEEIVAFARKYEILLVHDLCYAELAFDGYQPTSLLEIPGAKDIGVEFHT
LSKTYNMAGWRVGFVVGNRHVIQGLRTLKTNLDYGIFAALQTAAETALQLPDIYLHEVQQRYRTRRDFLIQGLGELGWDV
PKTKATMYLWVKCPVGMGSTDFALNLLQQTGVVVTPGNAFGVAGEGYVRISLIADCDRLGEALDRIKQAGIRYRPEALVS
APE
>Mature_402_residues
SFDWITPADRIQQLPPYVFARLDELKAKAREQGIDLIDLGMGNPDGATPQPVVDAAIQALQDPKNHGYPPFEGTASFRRA
ITNWYNRRYGVVLDPDSEALPLLGSKEGLSHLAIAYVNPGDVVLVPSPAYPAHFRGPVIAGGTVHSLILKPENDWLIDLT
AIPEEVARKAKILYFNYPSNPTGATAPREFFEEIVAFARKYEILLVHDLCYAELAFDGYQPTSLLEIPGAKDIGVEFHTL
SKTYNMAGWRVGFVVGNRHVIQGLRTLKTNLDYGIFAALQTAAETALQLPDIYLHEVQQRYRTRRDFLIQGLGELGWDVP
KTKATMYLWVKCPVGMGSTDFALNLLQQTGVVVTPGNAFGVAGEGYVRISLIADCDRLGEALDRIKQAGIRYRPEALVSA
PE

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=23.0379746835443, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=23.0379746835443, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI56713256, Length=333, Percent_Identity=25.5255255255255, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI56713254, Length=334, Percent_Identity=25.4491017964072, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881281, Length=378, Percent_Identity=21.4285714285714, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4507369, Length=405, Percent_Identity=23.2098765432099, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=45.9390862944162, Blast_Score=363, Evalue=1e-102,
Organism=Escherichia coli, GI1786816, Length=393, Percent_Identity=24.1730279898219, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788627, Length=389, Percent_Identity=25.9640102827763, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=419, Percent_Identity=23.3890214797136, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=419, Percent_Identity=23.3890214797136, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=329, Percent_Identity=23.7082066869301, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=385, Percent_Identity=26.2337662337662, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=23.3933161953728, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573069, Length=297, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=297, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=297, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=297, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859735, Length=397, Percent_Identity=23.1738035264484, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44523; Mature: 44392

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDWITPADRIQQLPPYVFARLDELKAKAREQGIDLIDLGMGNPDGATPQPVVDAAIQA
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
LQDPKNHGYPPFEGTASFRRAITNWYNRRYGVVLDPDSEALPLLGSKEGLSHLAIAYVNP
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEECC
GDVVLVPSPAYPAHFRGPVIAGGTVHSLILKPENDWLIDLTAIPEEVARKAKILYFNYPS
CCEEEECCCCCCCCCCCCEEECCCEEEEEEECCCCCEEEEECCCHHHHCCEEEEEEECCC
NPTGATAPREFFEEIVAFARKYEILLVHDLCYAELAFDGYQPTSLLEIPGAKDIGVEFHT
CCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEE
LSKTYNMAGWRVGFVVGNRHVIQGLRTLKTNLDYGIFAALQTAAETALQLPDIYLHEVQQ
HHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RYRTRRDFLIQGLGELGWDVPKTKATMYLWVKCPVGMGSTDFALNLLQQTGVVVTPGNAF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCE
GVAGEGYVRISLIADCDRLGEALDRIKQAGIRYRPEALVSAPE
ECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHCCCCC
>Mature Secondary Structure 
SFDWITPADRIQQLPPYVFARLDELKAKAREQGIDLIDLGMGNPDGATPQPVVDAAIQA
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
LQDPKNHGYPPFEGTASFRRAITNWYNRRYGVVLDPDSEALPLLGSKEGLSHLAIAYVNP
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEECC
GDVVLVPSPAYPAHFRGPVIAGGTVHSLILKPENDWLIDLTAIPEEVARKAKILYFNYPS
CCEEEECCCCCCCCCCCCEEECCCEEEEEEECCCCCEEEEECCCHHHHCCEEEEEEECCC
NPTGATAPREFFEEIVAFARKYEILLVHDLCYAELAFDGYQPTSLLEIPGAKDIGVEFHT
CCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEE
LSKTYNMAGWRVGFVVGNRHVIQGLRTLKTNLDYGIFAALQTAAETALQLPDIYLHEVQQ
HHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RYRTRRDFLIQGLGELGWDVPKTKATMYLWVKCPVGMGSTDFALNLLQQTGVVVTPGNAF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCE
GVAGEGYVRISLIADCDRLGEALDRIKQAGIRYRPEALVSAPE
ECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA