Click here to switch to the map view.

The map label for this gene is frr

Identifier: 17228703

GI number: 17228703

Start: 1423008

End: 1423556

Strand: Direct

Name: frr

Synonym: alr1208

Alternate gene names: 17228703

Gene position: 1423008-1423556 (Clockwise)

Preceding gene: 17228702

Following gene: 17228704

Centisome position: 22.19

GC content: 42.99

Gene sequence:

>549_bases
GTGAAATTAGCTGAAGCTGAAAGTAAAATGCAACATACTGTTGAGGCGACTCAACGGGCATTTAATACAATTCGTACTGG
CCGCGCCAATGCCAGCTTGTTAGATAAGGTGTTAGTAGACTACTACGGTTCACCTACACCCTTAAAATCTCTGGCAAATA
TTAGCACGCCAGACGCAACGACAATACTGATTCAGCCTTACGATAAGAGCAGTTTAAATATTGTCGAAAAAGCCATTTCT
CTCTCCGATGTTGGTTTAACACCAAGTAACGATGGTGCTGTTATTCGCTTGAATATACCACCATTGACAAGCGATCGCCG
CAAAGAACTAGTCAAAATTGCAGCCAAGTACGCGGAAGAAGGGCGTGTTGCTATTCGTAACATCCGCCGTGATGCCGTAG
ACTCAATTCGCAAGCTAGAGAAAAACGCCGAGGTTTCCGAAGATGAAGCCAAAGACCAACAAGACAAACTGCAAAAGCTA
ACCAATAAATACACCGCCAGAATCGATGAATTGTTGGTAGAAAAAGAAAAAGACATCTCCACTGTTTAA

Upstream 100 bases:

>100_bases
GAAAATAATATCCCTATTCTTGTATTTGACCTAACAACGCGGGGTAATATTCGCCGCGCCGTTTTAGGAGAATCTATCGG
TACCCTTGTGGGAGGTTCTT

Downstream 100 bases:

>100_bases
ACAGTTTTCAGGCTGAGGAACATGAGATTCTTCAGCCTTTTTTATCTGTAAGTGTTGACTGTTGATCAGTCTCAGAAATT
TTGAATTTTGAATTTTGAAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKLAEAESKMQHTVEATQRAFNTIRTGRANASLLDKVLVDYYGSPTPLKSLANISTPDATTILIQPYDKSSLNIVEKAIS
LSDVGLTPSNDGAVIRLNIPPLTSDRRKELVKIAAKYAEEGRVAIRNIRRDAVDSIRKLEKNAEVSEDEAKDQQDKLQKL
TNKYTARIDELLVEKEKDISTV

Sequences:

>Translated_182_residues
MKLAEAESKMQHTVEATQRAFNTIRTGRANASLLDKVLVDYYGSPTPLKSLANISTPDATTILIQPYDKSSLNIVEKAIS
LSDVGLTPSNDGAVIRLNIPPLTSDRRKELVKIAAKYAEEGRVAIRNIRRDAVDSIRKLEKNAEVSEDEAKDQQDKLQKL
TNKYTARIDELLVEKEKDISTV
>Mature_182_residues
MKLAEAESKMQHTVEATQRAFNTIRTGRANASLLDKVLVDYYGSPTPLKSLANISTPDATTILIQPYDKSSLNIVEKAIS
LSDVGLTPSNDGAVIRLNIPPLTSDRRKELVKIAAKYAEEGRVAIRNIRRDAVDSIRKLEKNAEVSEDEAKDQQDKLQKL
TNKYTARIDELLVEKEKDISTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Escherichia coli, GI1786368, Length=175, Percent_Identity=46.8571428571429, Blast_Score=163, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=28.3236994219653, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_NOSS1 (Q8YXK4)

Other databases:

- EMBL:   BA000019
- PIR:   AE1957
- RefSeq:   NP_485251.1
- ProteinModelPortal:   Q8YXK4
- SMR:   Q8YXK4
- STRING:   Q8YXK4
- GeneID:   1104803
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr1208
- NMPDR:   fig|103690.1.peg.1518
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q8YXK4
- ProtClustDB:   PRK00083
- BioCyc:   NSP103690:ALR1208-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20237; Mature: 20237

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAEAESKMQHTVEATQRAFNTIRTGRANASLLDKVLVDYYGSPTPLKSLANISTPDAT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCE
TILIQPYDKSSLNIVEKAISLSDVGLTPSNDGAVIRLNIPPLTSDRRKELVKIAAKYAEE
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHC
GRVAIRNIRRDAVDSIRKLEKNAEVSEDEAKDQQDKLQKLTNKYTARIDELLVEKEKDIS
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TV
CC
>Mature Secondary Structure
MKLAEAESKMQHTVEATQRAFNTIRTGRANASLLDKVLVDYYGSPTPLKSLANISTPDAT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCE
TILIQPYDKSSLNIVEKAISLSDVGLTPSNDGAVIRLNIPPLTSDRRKELVKIAAKYAEE
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHC
GRVAIRNIRRDAVDSIRKLEKNAEVSEDEAKDQQDKLQKLTNKYTARIDELLVEKEKDIS
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840