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The map label for this gene is yciC [H]

Identifier: 17228588

GI number: 17228588

Start: 1280559

End: 1281683

Strand: Direct

Name: yciC [H]

Synonym: alr1093

Alternate gene names: 17228588

Gene position: 1280559-1281683 (Clockwise)

Preceding gene: 17228581

Following gene: 17228589

Centisome position: 19.97

GC content: 41.07

Gene sequence:

>1125_bases
ATGCAATCAGCAGTCACCGATAATTCTCAACCAATGGATGCTCCTAAACAAGGAATGCCAGTCACGATTATTACTGGATT
TCTCGGTAGTGGCAAGACAACTTTACTAAATCATATTCTCAGCAATCAACAGGGCTTAAAAACCGCCGTTTTGGTCAACG
AGTTTGGAGAAATCGGCATTGACAACGAGTTAATTGTTTCCACCGATGAGAACATGGTGGAACTGAGTAACGGTTGTATC
TGCTGCACTATTAATAATGATTTAGTAGATGCTGTATACAAGGTTTTAGAAAGGGAAGAAAAGCTAGATTATCTAGTTGT
AGAAACCACTGGACTAGCTGACCCCCTACCAGTAGCCCTAACATTTTTGGGTACAGAATTGCGGGATTTAACCCGGTTAG
ATTCCATTATTACTGTAGTAGATGCAGCCAATTACAGTTTAGATTTATTCAACTCGCAAGCGGCTTACAGCCAAATTGCC
TACGGTGATGTCATTCTGTTGAACAAGACAGATTTGGTTGATGAAGCCAGCTTGAATGATTTGGAAAGAAAAATCAATGA
AGTTAAAGAAGGTGCGAGGATTTTAAGAACGAAGCGATCGCAAGTTCCCCTCCCTTTAATCTTAAGTGTGGGTCTATTTG
AGTCGGATAAGTATTATGATGCAGCCGATGAGCATAGTCACGACCACCATGACCACGACCACGACCATTCAGCTTGTGAG
CATGATCATCATGACCATGATCATTCAGCTTGCGGTCACGACCATCACGACCACGAACACCATCATCACCACTCCGACCA
TTTAGAAAACGATGGTTTCACCTCAATATCTTTCCAAAGTGATCAACCTTTTTCGATTCGCAAGTTTCAATATTTCCTAG
ATAACCAGCTATCCACAAATATTTTCCGAGCCAAGGGGATTATGTGGTTTGATGAAAGTCCCAAACGTCACATTTTCCAC
CTCTGTGGTAAACGTTTTACTTTAGATGATGAAGAATGGAAGGGTGAACCAAAAAACCAAATAGTGTTGATTGGTCAAAA
TTTAGATCGTGAAACCTTACTCACTCAATTAGAAAACTGCGTTTGTCTTCCTTCTACCAGCAGAGGTCAAGGTTTTGGGA
AATAG

Upstream 100 bases:

>100_bases
AGTGTTTTCTGGACTATCTCCGCTACCATTTTGCCATTCTGCTCGAAACAAGCTGCCCTGAAAGTCCTCTCGTATCTTTT
AATTTTGCGACCATATTGCT

Downstream 100 bases:

>100_bases
AACGGATAAGCTAATGTGCGCCTAAATTGCATAACTACTAATAAGGGATGTTGACTGTTAACGGTTAACTGTTAACGGTC
AACAGCCTTCACTATGGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MQSAVTDNSQPMDAPKQGMPVTIITGFLGSGKTTLLNHILSNQQGLKTAVLVNEFGEIGIDNELIVSTDENMVELSNGCI
CCTINNDLVDAVYKVLEREEKLDYLVVETTGLADPLPVALTFLGTELRDLTRLDSIITVVDAANYSLDLFNSQAAYSQIA
YGDVILLNKTDLVDEASLNDLERKINEVKEGARILRTKRSQVPLPLILSVGLFESDKYYDAADEHSHDHHDHDHDHSACE
HDHHDHDHSACGHDHHDHEHHHHHSDHLENDGFTSISFQSDQPFSIRKFQYFLDNQLSTNIFRAKGIMWFDESPKRHIFH
LCGKRFTLDDEEWKGEPKNQIVLIGQNLDRETLLTQLENCVCLPSTSRGQGFGK

Sequences:

>Translated_374_residues
MQSAVTDNSQPMDAPKQGMPVTIITGFLGSGKTTLLNHILSNQQGLKTAVLVNEFGEIGIDNELIVSTDENMVELSNGCI
CCTINNDLVDAVYKVLEREEKLDYLVVETTGLADPLPVALTFLGTELRDLTRLDSIITVVDAANYSLDLFNSQAAYSQIA
YGDVILLNKTDLVDEASLNDLERKINEVKEGARILRTKRSQVPLPLILSVGLFESDKYYDAADEHSHDHHDHDHDHSACE
HDHHDHDHSACGHDHHDHEHHHHHSDHLENDGFTSISFQSDQPFSIRKFQYFLDNQLSTNIFRAKGIMWFDESPKRHIFH
LCGKRFTLDDEEWKGEPKNQIVLIGQNLDRETLLTQLENCVCLPSTSRGQGFGK
>Mature_374_residues
MQSAVTDNSQPMDAPKQGMPVTIITGFLGSGKTTLLNHILSNQQGLKTAVLVNEFGEIGIDNELIVSTDENMVELSNGCI
CCTINNDLVDAVYKVLEREEKLDYLVVETTGLADPLPVALTFLGTELRDLTRLDSIITVVDAANYSLDLFNSQAAYSQIA
YGDVILLNKTDLVDEASLNDLERKINEVKEGARILRTKRSQVPLPLILSVGLFESDKYYDAADEHSHDHHDHDHDHSACE
HDHHDHDHSACGHDHHDHEHHHHHSDHLENDGFTSISFQSDQPFSIRKFQYFLDNQLSTNIFRAKGIMWFDESPKRHIFH
LCGKRFTLDDEEWKGEPKNQIVLIGQNLDRETLLTQLENCVCLPSTSRGQGFGK

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=368, Percent_Identity=31.5217391304348, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI33469141, Length=368, Percent_Identity=31.5217391304348, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI148727351, Length=368, Percent_Identity=31.25, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI146231952, Length=370, Percent_Identity=31.8918918918919, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI223941779, Length=213, Percent_Identity=40.3755868544601, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI223941776, Length=342, Percent_Identity=30.7017543859649, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI119120938, Length=146, Percent_Identity=41.0958904109589, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI87082430, Length=345, Percent_Identity=31.5942028985507, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1788499, Length=167, Percent_Identity=34.1317365269461, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=244, Percent_Identity=33.1967213114754, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 42141; Mature: 42141

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAVTDNSQPMDAPKQGMPVTIITGFLGSGKTTLLNHILSNQQGLKTAVLVNEFGEIGI
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
DNELIVSTDENMVELSNGCICCTINNDLVDAVYKVLEREEKLDYLVVETTGLADPLPVAL
CCCEEEECCCCEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
TFLGTELRDLTRLDSIITVVDAANYSLDLFNSQAAYSQIAYGDVILLNKTDLVDEASLND
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCEEEEECCCCCCCCHHHH
LERKINEVKEGARILRTKRSQVPLPLILSVGLFESDKYYDAADEHSHDHHDHDHDHSACE
HHHHHHHHHHHHHHHHHHHCCCCEEHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
HDHHDHDHSACGHDHHDHEHHHHHSDHLENDGFTSISFQSDQPFSIRKFQYFLDNQLSTN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHCC
IFRAKGIMWFDESPKRHIFHLCGKRFTLDDEEWKGEPKNQIVLIGQNLDRETLLTQLENC
HHHHCCEEEECCCCHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHCE
VCLPSTSRGQGFGK
EECCCCCCCCCCCC
>Mature Secondary Structure
MQSAVTDNSQPMDAPKQGMPVTIITGFLGSGKTTLLNHILSNQQGLKTAVLVNEFGEIGI
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
DNELIVSTDENMVELSNGCICCTINNDLVDAVYKVLEREEKLDYLVVETTGLADPLPVAL
CCCEEEECCCCEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
TFLGTELRDLTRLDSIITVVDAANYSLDLFNSQAAYSQIAYGDVILLNKTDLVDEASLND
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCEEEEECCCCCCCCHHHH
LERKINEVKEGARILRTKRSQVPLPLILSVGLFESDKYYDAADEHSHDHHDHDHDHSACE
HHHHHHHHHHHHHHHHHHHCCCCEEHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
HDHHDHDHSACGHDHHDHEHHHHHSDHLENDGFTSISFQSDQPFSIRKFQYFLDNQLSTN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHCC
IFRAKGIMWFDESPKRHIFHLCGKRFTLDDEEWKGEPKNQIVLIGQNLDRETLLTQLENC
HHHHCCEEEECCCCHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHCE
VCLPSTSRGQGFGK
EECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]