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The map label for this gene is fimH

Identifier: 16763927

GI number: 16763927

Start: 608675

End: 609682

Strand: Direct

Name: fimH

Synonym: STM0547

Alternate gene names: 16763927

Gene position: 608675-609682 (Clockwise)

Preceding gene: 16763926

Following gene: 16763928

Centisome position: 12.53

GC content: 51.69

Gene sequence:

>1008_bases
ATGAAAATATACTCAGCGCTATTGCTGGCGGGGACCGCGCTCTTTTTCACCCATCCCGCGCTGGCGACGGTTTGCCGTAA
TTCAAACGGGACGGCGACCGATATCTTTTACGACCTGTCAGATGTTTTCACCAGCGGCAATAATCAGCCGGGACAGGTGG
TGACGCTGCCGGAAAAATCAGGTTGGGTCGGCGTAAACGCGACGTGCCCGGCGGGGACAACGGTGAATTATACCTACCGA
AGCTATGTATCAGAATTACCGGTACAAAGTACCGAAGGAAATTTTAAATACCTCAAGTTGAATGACTACCTTCTGGGCGC
GATGAGCATCACCGATAGTGTCGCTGGCGTATTTTATCCGCCCCGTAACTATATTCTCATGGGCGTCGACTATAACGTGT
CGCAGCAAAAGCCGTTTGGCGTGCAGGACTCAAAGCTGGTTTTTAAATTAAAAGTGATACGGCCTTTTATTAATATGGTG
ACGATCCCTCGCCAGACAATGTTTACCGTCTATGTGACGACCTCTACCGGCGACGCGTTGAGCACGCCGGTATATACCAT
TAGCTACAGCGGCAAAGTGGAAGTGCCGCAAAACTGTGAAGTGAATGCCGGACAGGTCGTGGAGTTTGATTTCGGCGATA
TCGGCGCGTCGTTATTTAGTCAGGCGGGGGCGGGTAATCGTCCGCAAGGCGTCACGCCGCAAACGAAAACCATTGCTATC
AAATGTACCAACGTCGCGGCGCAGGCCTATTTATCGATGCGGCTTGAAGCCGAAAAGGCCTCAGGGCAGGCGATGGTGTC
CGATAATCCGGATTTAGGCTTTGTGGTTGCTAATAGCAACGGTACGCCGCTTACACCCAATAATTTGTCGAGTAAAATTC
CGTTTCATCTTGATGATAACGCCGCCGCTCGCGTAGGTATTCGCGCCTGGCCAATCAGCGTGACGGGGATTAAACCGGCG
GAAGGGCCGTTTACTGCGCGCGGCTATCTACGAGTCGATTATGATTAA

Upstream 100 bases:

>100_bases
GTATCGCCCCTTACGCCCTGGCGGAGGATAGCCTGAAGCAGGCGATTACGATAGCCAGCGCAACCTGTATCCGTCCGGCG
TCATAAAAGGAAAAATAGAG

Downstream 100 bases:

>100_bases
GGAGGCATAATGATCCTTCGGCGCGTTTTCATCGCTATCGGTTGTGTTTTGTTCAGCCCGCTGAGTCAGGCCAACTCATC
TCTGGGCGAAGTGAATATTG

Product: minor fimbrial subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKSGWVGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYPPRNYILMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMV
TIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGIKPA
EGPFTARGYLRVDYD

Sequences:

>Translated_335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKSGWVGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYPPRNYILMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMV
TIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGIKPA
EGPFTARGYLRVDYD
>Mature_335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKSGWVGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYPPRNYILMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMV
TIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGIKPA
EGPFTARGYLRVDYD

Specific function: Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Seems to be a mannose-binding adhesin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI145693100, Length=326, Percent_Identity=69.9386503067485, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1787173, Length=196, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789534, Length=307, Percent_Identity=28.0130293159609, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIMH_SALTY (P37925)

Other databases:

- EMBL:   L19338
- EMBL:   AE006468
- RefSeq:   NP_459542.1
- ProteinModelPortal:   P37925
- PRIDE:   P37925
- GeneID:   1252067
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM0547
- NMPDR:   fig|99287.1.peg.532
- HOGENOM:   HBG416521
- OMA:   PPRNYIR
- ProtClustDB:   PRK15199
- BioCyc:   STYP99287:STM0547-MONOMER
- GO:   GO:0009289
- InterPro:   IPR008966

Pfam domain/function: SSF49401 Adhes_bact

EC number: NA

Molecular weight: Translated: 36102; Mature: 36102

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKS
CCHHHHHHHHHHHHHHCCHHHHHHEECCCCCEEEEEEEHHHHHHCCCCCCCEEEECCCCC
GWVGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYP
CEEEEEEECCCCCEEEEEHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECCCCCCEEEEC
PRNYILMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMVTIPRQTMFTVYVTTSTGDAL
CCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEHHHHHHHEECCCCEEEEEEEEECCCCCC
STPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
CCCEEEEEECCEEECCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDN
EEECHHHEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCC
AAARVGIRAWPISVTGIKPAEGPFTARGYLRVDYD
CCEEEEEEEEEEEEECCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKS
CCHHHHHHHHHHHHHHCCHHHHHHEECCCCCEEEEEEEHHHHHHCCCCCCCEEEECCCCC
GWVGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYP
CEEEEEEECCCCCEEEEEHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECCCCCCEEEEC
PRNYILMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMVTIPRQTMFTVYVTTSTGDAL
CCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEHHHHHHHEECCCCEEEEEEEEECCCCCC
STPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
CCCEEEEEECCEEECCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDN
EEECHHHEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCC
AAARVGIRAWPISVTGIKPAEGPFTARGYLRVDYD
CCEEEEEEEEEEEEECCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609