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The map label for this gene is fimC

Identifier: 16763925

GI number: 16763925

Start: 605325

End: 606017

Strand: Direct

Name: fimC

Synonym: STM0545

Alternate gene names: 16763925

Gene position: 605325-606017 (Clockwise)

Preceding gene: 16763924

Following gene: 16763926

Centisome position: 12.46

GC content: 50.36

Gene sequence:

>693_bases
ATGCTGAATAGTATAAAAGTAGGCTTTATTGTTCTTCTCACGTTATTTACTTCGCTGAACGTACAGGCGGCGGGGGGGAT
TGCATTAGGCGCCACGCGCGTTATTTATCCCTCGGCGGCGAAGCAGACTTCTCTGGCAATCAGTAATAGCGATACTCAAG
AACGTTACCTCGTCAATTCATGGATCGAAAATAACGCTGGGCAGAAAGAAAAAACGTTTATCGTTACGCCGCCTTTATTC
GTCAGCGAGCCCAAAAGTGAAAACACGCTGCGTATTATCTACGCCGGGCAACCGCTACCCGGGGATCGGGAGTCGTTATT
CTGGATGAACGTGAAAGCCATCCCGTCGGTCGATAAAAGTCATATTGAAGGAAAAAACGTTCTGCAACTGGCGATTCTGT
CGCGCATCAAACTGTTCGTGCGTCCGGCGAATTTGCCGCAGACGCCGGAAGACGCGCCGACCTTGCTGAAATTTTCCCGT
GTCGGCAACCATCTCAAGATAACCAACCCATCTGCTTATTACCTCACGCTGGTCAATATCAGCGTGGGCGCGAAAAAGAT
TGATAACGTGATGATCGCGCCAAAAAGCGACATGCAAATTCCCTTACCGACTGGCGCGCAGGGCAACGTGACATTTCAGT
CCGTCAATGATTACGGCGCATTGACGTCGGCGACAACGGCCAGTCTCGGTTAA

Upstream 100 bases:

>100_bases
AATATGACGCCGGGACGAATTCATTCAGAAGTGTGGTTTACGCTGGTTTACCCATGAATTTTCTTGCCGACGTGACTCAA
TGCAAAAGGTATTTTTTACC

Downstream 100 bases:

>100_bases
GCAGAGAGCGTGAAGCCACACGAGAACACGATGAAGAAGACAACCTGGTTTGCAGGGCGATTTCCCGGCTATGTATCACC
GTTAAGCAGCGTGGCGCTGT

Product: periplasmic chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLNSIKVGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNSWIENNAGQKEKTFIVTPPLF
VSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKSHIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSR
VGNHLKITNPSAYYLTLVNISVGAKKIDNVMIAPKSDMQIPLPTGAQGNVTFQSVNDYGALTSATTASLG

Sequences:

>Translated_230_residues
MLNSIKVGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNSWIENNAGQKEKTFIVTPPLF
VSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKSHIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSR
VGNHLKITNPSAYYLTLVNISVGAKKIDNVMIAPKSDMQIPLPTGAQGNVTFQSVNDYGALTSATTASLG
>Mature_230_residues
MLNSIKVGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNSWIENNAGQKEKTFIVTPPLF
VSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKSHIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSR
VGNHLKITNPSAYYLTLVNISVGAKKIDNVMIAPKSDMQIPLPTGAQGNVTFQSVNDYGALTSATTASLG

Specific function: Required for the biogenesis of type 1 fimbriae. Binds and interact with fimH

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain

Homologues:

Organism=Escherichia coli, GI1786743, Length=229, Percent_Identity=61.5720524017467, Blast_Score=301, Evalue=3e-83,
Organism=Escherichia coli, GI1790771, Length=231, Percent_Identity=48.0519480519481, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1787171, Length=219, Percent_Identity=40.1826484018265, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1789532, Length=228, Percent_Identity=39.9122807017544, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786936, Length=228, Percent_Identity=36.8421052631579, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786333, Length=213, Percent_Identity=34.7417840375587, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87081806, Length=237, Percent_Identity=31.2236286919831, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788428, Length=231, Percent_Identity=30.7359307359307, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788677, Length=235, Percent_Identity=32.3404255319149, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI87082203, Length=228, Percent_Identity=30.2631578947368, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIMC_SALTY (P37923)

Other databases:

- EMBL:   L19338
- EMBL:   AE006468
- RefSeq:   NP_459540.1
- ProteinModelPortal:   P37923
- SMR:   P37923
- PRIDE:   P37923
- GeneID:   1252065
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM0545
- NMPDR:   fig|99287.1.peg.530
- HOGENOM:   HBG758617
- OMA:   YLIISTS
- ProtClustDB:   PRK15195
- BioCyc:   STYP99287:STM0545-MONOMER
- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147
- Gene3D:   G3DSA:2.60.40.360
- Gene3D:   G3DSA:2.60.40.1070
- PRINTS:   PR00969

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N; SSF49354 PapD-like; SSF49584 Pili_assmbl_chaperone_C_bac

EC number: NA

Molecular weight: Translated: 24868; Mature: 24868

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSIKVGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNS
CCCCCHHHHHHHHHHHHHCCEEECCCEEECCEEEEECCCCCCEEEEECCCCCHHHHHHHH
WIENNAGQKEKTFIVTPPLFVSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKS
HHHCCCCCCCCEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCHH
HIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSRVGNHLKITNPSAYYLTLVNI
HCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCEEEEEEEEE
SVGAKKIDNVMIAPKSDMQIPLPTGAQGNVTFQSVNDYGALTSATTASLG
ECCCHHHCCEEEECCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNSIKVGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNS
CCCCCHHHHHHHHHHHHHCCEEECCCEEECCEEEEECCCCCCEEEEECCCCCHHHHHHHH
WIENNAGQKEKTFIVTPPLFVSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKS
HHHCCCCCCCCEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCHH
HIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSRVGNHLKITNPSAYYLTLVNI
HCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCEEEEEEEEE
SVGAKKIDNVMIAPKSDMQIPLPTGAQGNVTFQSVNDYGALTSATTASLG
ECCCHHHCCEEEECCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609