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The map label for this gene is ptxR [C]

Identifier: 218929873

GI number: 218929873

Start: 3139529

End: 3140422

Strand: Reverse

Name: ptxR [C]

Synonym: YPO2807

Alternate gene names: 218929873

Gene position: 3140422-3139529 (Counterclockwise)

Preceding gene: 218929876

Following gene: 218929870

Centisome position: 67.48

GC content: 49.55

Gene sequence:

>894_bases
ATGCTAAAAGAAAACTTCAATGAACTGCAGAGCTTTCTTGTTGTTGCTAGAGAGAGAAGTTTTACCAAAGCAGCAGGTAA
GCTGGGGGTTTCTCAGTCGGCACTCAGCCACGCAATTAAGGGACTGGAAGAAAGATTAAACCTACGCCTTCTGACCCGAA
CAACGCGAAGTGTCGCTCCCACAGAAGCTGGTGAGCGAATTATTGCCTGCCTGGAACCTCGTCTGGCAGATCTTGAACAA
GAGTTGGAAACCCTTCTCCAACTGAACGGTACTGTATCAGGCAATATCCGGCTCTCTGCGGGAGAGCACGCAGCACGTAG
CTTGTTGTGGCCAAAGTTAAAACCATTTCTCAGAAAATACCCGGAAATCAATGTCGAACTGGTGGTTGATAATGGTTTCG
TCAATATCGTAGATGGCCGCTTCGATGCCGGCGTTCGTCTTGGCGAGAGTGTCGATAAGGACATGATTGCCGTAAAGATC
GGGCCGGAAATGCGTATGGCCGTCGTCGGCTCGCCAGAATACTTTATGGCAAACGCCATTCCCGTCACGCCACATGAATT
ACAGCATCATCGCTGCATTAATATGCGGCTGCCCACCGCCGGAGGTTTGTATCACTGGGAGTTTGAGAAAGAAGGCAAGC
CGCTGCGTGTGAAAGTTGAAGGCCAGTTGACGCTGAACATCCTGCCAGAAAGGATAGACGCGGCGCAGTCAGGATTTGGC
CTTGCTTGCGTGCCAGAGGATTCGATTCAGGCATTCTTAAGATCCGGGAAACTTATTCAGGTGCTGGAAGCGTGGTGTCC
ATCTTTCCCTGGTTATTACCTTTACTACCCAAGTAGAAAACAGCACCCACCTGTTTTTGCGCTTATGATAGATGCACTGC
GTTATTCGGATTAA

Upstream 100 bases:

>100_bases
TGACCATAAACTCTCCTGAATCAGGAGAGCAGATTACCCCCTGGATCTGATTTCAGGCGTTGGGTGTGGATCACTATTGC
ACCGTTCGTTACAATAGCCA

Downstream 100 bases:

>100_bases
CTGGCTTACGGATTATCGTAAGCCAGATGAAATTTGAGCGACTACAATTAAGTATTAACGACCCACTCGAGCCTGCATGG
CCGCAGGATAACGCTCTCCC

Product: putative LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLKENFNELQSFLVVARERSFTKAAGKLGVSQSALSHAIKGLEERLNLRLLTRTTRSVAPTEAGERIIACLEPRLADLEQ
ELETLLQLNGTVSGNIRLSAGEHAARSLLWPKLKPFLRKYPEINVELVVDNGFVNIVDGRFDAGVRLGESVDKDMIAVKI
GPEMRMAVVGSPEYFMANAIPVTPHELQHHRCINMRLPTAGGLYHWEFEKEGKPLRVKVEGQLTLNILPERIDAAQSGFG
LACVPEDSIQAFLRSGKLIQVLEAWCPSFPGYYLYYPSRKQHPPVFALMIDALRYSD

Sequences:

>Translated_297_residues
MLKENFNELQSFLVVARERSFTKAAGKLGVSQSALSHAIKGLEERLNLRLLTRTTRSVAPTEAGERIIACLEPRLADLEQ
ELETLLQLNGTVSGNIRLSAGEHAARSLLWPKLKPFLRKYPEINVELVVDNGFVNIVDGRFDAGVRLGESVDKDMIAVKI
GPEMRMAVVGSPEYFMANAIPVTPHELQHHRCINMRLPTAGGLYHWEFEKEGKPLRVKVEGQLTLNILPERIDAAQSGFG
LACVPEDSIQAFLRSGKLIQVLEAWCPSFPGYYLYYPSRKQHPPVFALMIDALRYSD
>Mature_297_residues
MLKENFNELQSFLVVARERSFTKAAGKLGVSQSALSHAIKGLEERLNLRLLTRTTRSVAPTEAGERIIACLEPRLADLEQ
ELETLLQLNGTVSGNIRLSAGEHAARSLLWPKLKPFLRKYPEINVELVVDNGFVNIVDGRFDAGVRLGESVDKDMIAVKI
GPEMRMAVVGSPEYFMANAIPVTPHELQHHRCINMRLPTAGGLYHWEFEKEGKPLRVKVEGQLTLNILPERIDAAQSGFG
LACVPEDSIQAFLRSGKLIQVLEAWCPSFPGYYLYYPSRKQHPPVFALMIDALRYSD

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=47.7966101694915, Blast_Score=304, Evalue=5e-84,
Organism=Escherichia coli, GI1787128, Length=279, Percent_Identity=40.1433691756272, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1786401, Length=280, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI145693193, Length=281, Percent_Identity=30.2491103202847, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI87081978, Length=268, Percent_Identity=28.7313432835821, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789440, Length=273, Percent_Identity=28.2051282051282, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788706, Length=288, Percent_Identity=26.3888888888889, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=25.5972696245734, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788748, Length=126, Percent_Identity=34.9206349206349, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786448, Length=290, Percent_Identity=25.5172413793103, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693105, Length=157, Percent_Identity=25.4777070063694, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787601, Length=134, Percent_Identity=29.1044776119403, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788297, Length=145, Percent_Identity=31.7241379310345, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787879, Length=203, Percent_Identity=27.0935960591133, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33223; Mature: 33223

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKENFNELQSFLVVARERSFTKAAGKLGVSQSALSHAIKGLEERLNLRLLTRTTRSVAP
CCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCC
TEAGERIIACLEPRLADLEQELETLLQLNGTVSGNIRLSAGEHAARSLLWPKLKPFLRKY
CHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEECCEEEECCHHHHHHHCCHHHHHHHHHC
PEINVELVVDNGFVNIVDGRFDAGVRLGESVDKDMIAVKIGPEMRMAVVGSPEYFMANAI
CCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEECCC
PVTPHELQHHRCINMRLPTAGGLYHWEFEKEGKPLRVKVEGQLTLNILPERIDAAQSGFG
CCCHHHHCCCEEEEEECCCCCCEEEEEECCCCCCEEEEEECEEEEEECCHHHHHHHCCCC
LACVPEDSIQAFLRSGKLIQVLEAWCPSFPGYYLYYPSRKQHPPVFALMIDALRYSD
EEECCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLKENFNELQSFLVVARERSFTKAAGKLGVSQSALSHAIKGLEERLNLRLLTRTTRSVAP
CCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCC
TEAGERIIACLEPRLADLEQELETLLQLNGTVSGNIRLSAGEHAARSLLWPKLKPFLRKY
CHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEECCEEEECCHHHHHHHCCHHHHHHHHHC
PEINVELVVDNGFVNIVDGRFDAGVRLGESVDKDMIAVKIGPEMRMAVVGSPEYFMANAI
CCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEECCC
PVTPHELQHHRCINMRLPTAGGLYHWEFEKEGKPLRVKVEGQLTLNILPERIDAAQSGFG
CCCHHHHCCCEEEEEECCCCCCEEEEEECCCCCCEEEEEECEEEEEECCHHHHHHHCCCC
LACVPEDSIQAFLRSGKLIQVLEAWCPSFPGYYLYYPSRKQHPPVFALMIDALRYSD
EEECCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]