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The map label for this gene is yajL [H]

Identifier: 218928021

GI number: 218928021

Start: 926307

End: 926885

Strand: Direct

Name: yajL [H]

Synonym: YPO0845

Alternate gene names: 218928021

Gene position: 926307-926885 (Clockwise)

Preceding gene: 218928020

Following gene: 218928023

Centisome position: 19.9

GC content: 49.74

Gene sequence:

>579_bases
ATGACGAAACACGTTGCCGTATTGCTGGCGCACGGTTTTGAAGAGGCAGAAGCCGTTATTTTTATCGACATCATGCGTCG
TCTGGATATCCGGGTTGATATTCTCTCCTGCGAAGCAACCACGGCCTTGAGCACCTATTTTGAAACGCCGATCAGCGCAG
ATGCGCTGTTAAGCGATCGTCTGGATCACCACTATGATGCGGTCATGATGCCCGGAGGCCCAAAAGGCACAGACAGCCTG
ACGGCAAACCCACAAGTGATTGCATTTTTAAGACGTCATATTGCTCAGGATAAATATATCTGCGCCTTGTGTTCATCTGG
GGCCAAGGTCTTGGCAGCTCATCATTTGCTGGCCGGGCGAACTTACAGTACTGGTGATAAGCTGGCTGATAAATTTGCTG
ATGGGGCCTATCTGGATCAGGATGTGGTGGTTGATGGCAAGTTTATTACAGCCAAAGGGCTGGGTGTCAGCTTTGAGTTT
GCCTTCACCGTGGCCCGCCATTTGCTCAGTGATAACCTGCCAAAAGTTGAGCACCAAGCCAGCCATATCTATTTTAAACA
TGGGTCAGCACAGACGTAA

Upstream 100 bases:

>100_bases
TGGTTCCGGCTAAAGCCGCCATGAAAAAAGTGATTCAGGATAAAATTAACGTCTGCGGCAGCGCTGGCAAACGGTAAAGC
GCCAGGAGAGGAAGCAGATT

Downstream 100 bases:

>100_bases
TTATCACCATTAGCCCCTGTACACGATGCTCTCCCCACGACGGCATTATCAGTACCATTTTCGTTTATATCGTCAGTAGC
ATTGCCGTTTATATAGCCAG

Product: ThiJ/PfpI family thiamine biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTKHVAVLLAHGFEEAEAVIFIDIMRRLDIRVDILSCEATTALSTYFETPISADALLSDRLDHHYDAVMMPGGPKGTDSL
TANPQVIAFLRRHIAQDKYICALCSSGAKVLAAHHLLAGRTYSTGDKLADKFADGAYLDQDVVVDGKFITAKGLGVSFEF
AFTVARHLLSDNLPKVEHQASHIYFKHGSAQT

Sequences:

>Translated_192_residues
MTKHVAVLLAHGFEEAEAVIFIDIMRRLDIRVDILSCEATTALSTYFETPISADALLSDRLDHHYDAVMMPGGPKGTDSL
TANPQVIAFLRRHIAQDKYICALCSSGAKVLAAHHLLAGRTYSTGDKLADKFADGAYLDQDVVVDGKFITAKGLGVSFEF
AFTVARHLLSDNLPKVEHQASHIYFKHGSAQT
>Mature_191_residues
TKHVAVLLAHGFEEAEAVIFIDIMRRLDIRVDILSCEATTALSTYFETPISADALLSDRLDHHYDAVMMPGGPKGTDSLT
ANPQVIAFLRRHIAQDKYICALCSSGAKVLAAHHLLAGRTYSTGDKLADKFADGAYLDQDVVVDGKFITAKGLGVSFEFA
FTVARHLLSDNLPKVEHQASHIYFKHGSAQT

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=171, Percent_Identity=32.7485380116959, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI31543380, Length=171, Percent_Identity=32.7485380116959, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI87081736, Length=192, Percent_Identity=27.6041666666667, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17558714, Length=158, Percent_Identity=30.379746835443, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531319, Length=164, Percent_Identity=28.6585365853659, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571932, Length=170, Percent_Identity=30, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24653499, Length=189, Percent_Identity=28.042328042328, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20959; Mature: 20828

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHVAVLLAHGFEEAEAVIFIDIMRRLDIRVDILSCEATTALSTYFETPISADALLSDR
CCCCEEEEEECCCCCCCCEEHEEHHHHCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHHH
LDHHYDAVMMPGGPKGTDSLTANPQVIAFLRRHIAQDKYICALCSSGAKVLAAHHLLAGR
HCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCC
TYSTGDKLADKFADGAYLDQDVVVDGKFITAKGLGVSFEFAFTVARHLLSDNLPKVEHQA
CCCCHHHHHHHHCCCCCCCCCEEECCEEEEECCCCEEHHHHHHHHHHHHHCCCCCCCCCC
SHIYFKHGSAQT
CEEEEECCCCCC
>Mature Secondary Structure 
TKHVAVLLAHGFEEAEAVIFIDIMRRLDIRVDILSCEATTALSTYFETPISADALLSDR
CCCEEEEEECCCCCCCCEEHEEHHHHCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHHH
LDHHYDAVMMPGGPKGTDSLTANPQVIAFLRRHIAQDKYICALCSSGAKVLAAHHLLAGR
HCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCC
TYSTGDKLADKFADGAYLDQDVVVDGKFITAKGLGVSFEFAFTVARHLLSDNLPKVEHQA
CCCCHHHHHHHHCCCCCCCCCEEECCEEEEECCCCEEHHHHHHHHHHHHHCCCCCCCCCC
SHIYFKHGSAQT
CEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]