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The map label for this gene is gatY [H]

Identifier: 218928020

GI number: 218928020

Start: 925429

End: 926283

Strand: Direct

Name: gatY [H]

Synonym: YPO0844

Alternate gene names: 218928020

Gene position: 925429-926283 (Clockwise)

Preceding gene: 218928019

Following gene: 218928021

Centisome position: 19.89

GC content: 50.18

Gene sequence:

>855_bases
ATGTTTTTGGTTTCTTCCCGAGAAATGTTACGTCAGGCACAGATCGGAGGCTACGCAATCCCAGCCTTCAACATCCATAA
TCTGGAGACCATTCAAGCCGTAGTTGAAACAGCGGCTGAAATGGCTTCTCCGGTCATTTTGGCCGGAACACCGAGCACCT
TTTCTTATGCGGGCACGGAATATCTGGTGCAGATCTGCCAACAAGCGGCACGTCATTACCGTATGCCTTTTGCACTGCAT
CTGGATCACCATGAGTCGTATGATGATATTACCCAGAAAGTCGCGGCGGGCATCAAATCCATAATGATTGATGGCTCGCA
TTTTAACTTTGAGCAAAATATCGCGCTGACACGTCAGGTGGTGGAGTATTGCCATCGCTGGGATGGTACTGTCGAAGCCG
AACTGGGGCGTCTGGGCGGTCAGGAGGATGATCTCACGGTTGATGAGAAAGATGCGCTGTATACTGATCCTGGTTCGGCA
GCACATTTTATTCAGGCGACAGGGATAGACTCTCTGGCCATTGCCATCGGCACTGCCCATGGGATGTACAAAGAGGCCCC
TAGCCTGGACTTTGATCGTCTGGCGCTCATTCGCCGCAATACGGATATCCCTCTGGTACTGCATGGCGGATCAGGGATCC
CAGATGAAGATGTGCGTCGTTGCATTGAATTGGGGATCAGTAAAGTGAATGTGGGTACAGAGCTAAAGATCGCATTCTCT
GGTGCACTGAAAGCCTATTTCCTTGAAAATAAAGGCGCGAATGATCCCCGTCACTATATGGTTCCGGCTAAAGCCGCCAT
GAAAAAAGTGATTCAGGATAAAATTAACGTCTGCGGCAGCGCTGGCAAACGGTAA

Upstream 100 bases:

>100_bases
ACTTTCGATGTGATGCAAATCTCTTTTATTTGATTTCTTTTTGTTTGTGTAAGCTTTTTTATGGTTAAATGAAAGGAAAT
GAAATCACGGAGGTTGAGTT

Downstream 100 bases:

>100_bases
AGCGCCAGGAGAGGAAGCAGATTATGACGAAACACGTTGCCGTATTGCTGGCGCACGGTTTTGAAGAGGCAGAAGCCGTT
ATTTTTATCGACATCATGCG

Product: tagatose-bisphosphate aldolase

Products: NA

Alternate protein names: TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MFLVSSREMLRQAQIGGYAIPAFNIHNLETIQAVVETAAEMASPVILAGTPSTFSYAGTEYLVQICQQAARHYRMPFALH
LDHHESYDDITQKVAAGIKSIMIDGSHFNFEQNIALTRQVVEYCHRWDGTVEAELGRLGGQEDDLTVDEKDALYTDPGSA
AHFIQATGIDSLAIAIGTAHGMYKEAPSLDFDRLALIRRNTDIPLVLHGGSGIPDEDVRRCIELGISKVNVGTELKIAFS
GALKAYFLENKGANDPRHYMVPAKAAMKKVIQDKINVCGSAGKR

Sequences:

>Translated_284_residues
MFLVSSREMLRQAQIGGYAIPAFNIHNLETIQAVVETAAEMASPVILAGTPSTFSYAGTEYLVQICQQAARHYRMPFALH
LDHHESYDDITQKVAAGIKSIMIDGSHFNFEQNIALTRQVVEYCHRWDGTVEAELGRLGGQEDDLTVDEKDALYTDPGSA
AHFIQATGIDSLAIAIGTAHGMYKEAPSLDFDRLALIRRNTDIPLVLHGGSGIPDEDVRRCIELGISKVNVGTELKIAFS
GALKAYFLENKGANDPRHYMVPAKAAMKKVIQDKINVCGSAGKR
>Mature_284_residues
MFLVSSREMLRQAQIGGYAIPAFNIHNLETIQAVVETAAEMASPVILAGTPSTFSYAGTEYLVQICQQAARHYRMPFALH
LDHHESYDDITQKVAAGIKSIMIDGSHFNFEQNIALTRQVVEYCHRWDGTVEAELGRLGGQEDDLTVDEKDALYTDPGSA
AHFIQATGIDSLAIAIGTAHGMYKEAPSLDFDRLALIRRNTDIPLVLHGGSGIPDEDVRRCIELGISKVNVGTELKIAFS
GALKAYFLENKGANDPRHYMVPAKAAMKKVIQDKINVCGSAGKR

Specific function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (T

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=283, Percent_Identity=59.3639575971731, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI87082041, Length=283, Percent_Identity=58.3038869257951, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1788072, Length=271, Percent_Identity=39.1143911439114, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1789293, Length=324, Percent_Identity=26.5432098765432, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322790, Length=278, Percent_Identity=26.978417266187, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000771
- InterPro:   IPR011288 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 31091; Mature: 31091

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVSSREMLRQAQIGGYAIPAFNIHNLETIQAVVETAAEMASPVILAGTPSTFSYAGTE
CEEECHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHH
YLVQICQQAARHYRMPFALHLDHHESYDDITQKVAAGIKSIMIDGSHFNFEQNIALTRQV
HHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
VEYCHRWDGTVEAELGRLGGQEDDLTVDEKDALYTDPGSAAHFIQATGIDSLAIAIGTAH
HHHHHHCCCCEEHHHHHCCCCCCCCEECCCCCEEECCCCCCCEEEECCCCHHHHHHHHHH
GMYKEAPSLDFDRLALIRRNTDIPLVLHGGSGIPDEDVRRCIELGISKVNVGTELKIAFS
HHHHCCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEECCCCEEEEEEC
GALKAYFLENKGANDPRHYMVPAKAAMKKVIQDKINVCGSAGKR
CCEEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFLVSSREMLRQAQIGGYAIPAFNIHNLETIQAVVETAAEMASPVILAGTPSTFSYAGTE
CEEECHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHH
YLVQICQQAARHYRMPFALHLDHHESYDDITQKVAAGIKSIMIDGSHFNFEQNIALTRQV
HHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
VEYCHRWDGTVEAELGRLGGQEDDLTVDEKDALYTDPGSAAHFIQATGIDSLAIAIGTAH
HHHHHHCCCCEEHHHHHCCCCCCCCEECCCCCEEECCCCCCCEEEECCCCHHHHHHHHHH
GMYKEAPSLDFDRLALIRRNTDIPLVLHGGSGIPDEDVRRCIELGISKVNVGTELKIAFS
HHHHCCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEECCCCEEEEEEC
GALKAYFLENKGANDPRHYMVPAKAAMKKVIQDKINVCGSAGKR
CCEEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA