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The map label for this gene is crgA [H]

Identifier: 218927862

GI number: 218927862

Start: 728935

End: 729846

Strand: Direct

Name: crgA [H]

Synonym: YPO0669

Alternate gene names: 218927862

Gene position: 728935-729846 (Clockwise)

Preceding gene: 218927861

Following gene: 218927864

Centisome position: 15.66

GC content: 53.07

Gene sequence:

>912_bases
ATGAAAGTCACGTTGGAAGAGTTGCAGGCATTTACCTCGGTAGTGGACTGCGGCTCTATCACGGCTGCGGCAGAGCAGCG
CAGCCAAACGACATCGGGGATTAGCCGGGCATTGAGTCGGCTAGAGCAGAAGCTGGCGACAACGTTGCTACGCCGTACGA
CTCGGCGTCTGGAGCTGACAGAAGAGGGGGCGCTGTTCCTCAGTCATGCGCGGCAGATTATCGGCGCAGTCGATGATGCT
GAAGAGCAAATTGCCCTGAGGCGGTTGAAGCCTGCTGGCCGGTTACGAGTTAATGCGGCAGCTCCTTTTATGCAACATGT
CATTGTGCCGATGATCACCGGTTTCCGTGCGTTGTATCCGCAAATCACGTTGGAATTGAATACCGACGATCTCAATATCG
ATCTGCTTGAGCAGCGCACTGACATTGCTATCCGTATCGGTGCGTTGAGGGATTCGACGATCCATGCCCGGCTGCTTGGT
GCCAGCCGGGTGCGTCTGCTTGCCAGCCCTAACTACCTACAACGTCACGGTACGCCTCACATCATTGAGGCACTGGCAGA
TCACAGCCTGCTGGGCTTTACTCAGCCCGAATTTCTTAATCAGTGGTCATTACCCCATTTACCCGGCGGGCGTTCGTCAA
TTATCCCCAACTTGGCGGCTTCCAGCGGTGAGACTCTGCGTTTACTGGCTTTACAGGGCGAAGGGATTGCCGAACTCTCT
GATTTCATGACCCGCGAGGATCAATTAGCTGGGCGTTTAGTCGAGGTTCTGGCTGATCAAATTCTAGAGACTTGGCAACC
GATCAACGCCGTTTATTACCGTAATACTCAGCTTGCTGCGCGCATTACCTGTTTTCTTGATTATGTTAGTGAACAGATTA
AGTTACAGGGGAGTCACTGGCTAAGAATATAA

Upstream 100 bases:

>100_bases
TCTGGCCGTTATGGATATGTTGTTGGCAAAGAAACGCTCGGAAGATCGCCGCAACTGGCTACAAGAGAAAGGGGATACTG
CTGAGATCGAGGTCTGATCG

Downstream 100 bases:

>100_bases
ATGAGGGAGGGGTAACGTATAAAACGGCCCTCCCCAGAGAGAGGAGGGCCGAACCGCTTAGCTGTTAACGTTTTCGGCTA
AGTGCTGACGATAGCGGGCA

Product: LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHIIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI

Sequences:

>Translated_303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHIIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI
>Mature_303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHIIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=43.5374149659864, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=30.5369127516779, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI145693193, Length=303, Percent_Identity=29.042904290429, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789440, Length=277, Percent_Identity=29.2418772563177, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=29.2096219931272, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=28.4745762711864, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787589, Length=304, Percent_Identity=25, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789173, Length=272, Percent_Identity=27.5735294117647, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788481, Length=302, Percent_Identity=26.8211920529801, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788706, Length=304, Percent_Identity=23.3552631578947, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=162, Percent_Identity=32.0987654320988, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786448, Length=184, Percent_Identity=27.1739130434783, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=25.968992248062, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33743; Mature: 33743

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
EEGALFLSHARQIIGAVDDAEEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
QITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLGASRVRLLASPNYLQRHGTPH
EEEEEECCCCCCEEHHHCCCCEEEEEECCCCCHHHHHHHCHHHEEEEECCCHHHHCCCHH
IIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
HHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHCCCHHCCCCCEEEEEEECCCCHHHHH
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHEECCCCE
LRI
ECC
>Mature Secondary Structure
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
EEGALFLSHARQIIGAVDDAEEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
QITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLGASRVRLLASPNYLQRHGTPH
EEEEEECCCCCCEEHHHCCCCEEEEEECCCCCHHHHHHHCHHHEEEEECCCHHHHCCCHH
IIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
HHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHCCCHHCCCCCEEEEEEECCCCHHHHH
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHEECCCCE
LRI
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]