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The map label for this gene is ubiC

Identifier: 218927516

GI number: 218927516

Start: 316696

End: 317220

Strand: Direct

Name: ubiC

Synonym: YPO0310

Alternate gene names: 218927516

Gene position: 316696-317220 (Clockwise)

Preceding gene: 218927514

Following gene: 218927517

Centisome position: 6.81

GC content: 50.86

Gene sequence:

>525_bases
ATGTTTATCGGCGATGCATCAATTTTAAAACCTATCCAATGGTGTGCTACCGAGCACCCTGAACTTCCTGCAGACATCGC
AGACTGGCTGATGGAGCTGGGTTCGATGACTCGACGCTTTGAGCAGCATTGCCAGCGTGTTCATGTCGAACCGCAACGTG
AATGCTTTATTACGCGTGATGCGCTAGGGGAAGAGGCTGAACATTTGCCCGTTAGTCAACGCTATTGGTTACGGGAAATT
GTCTTGTTTGGTGACAATGTGCCTTGGTTACTGGGGCGCACGGTTATCCCGGAGGAGACACTGTCTGGTCCGGATAGGGC
GCTGGTGGATTTAGGTACATTACCGCTAGGGCGTTACTTATTCAGTGGTGATGCCCTAACCCGGGACTATATTCACGTCG
GGCGGCAGGATAATCTATGGGCCAGGCGGTCTTTGCTACGCCTTTCAGGCAATCCACTGTTATTGACTGAGGTTTTTTTA
CCGGCATCGCCGCTTTATACCCATTGTGACTCTATACCCAAGTGA

Upstream 100 bases:

>100_bases
GTGACTGCCCGTGTCGCCGGGTACCTATTCTGCGCTACAATAGCGTTCTGTTTACTAATTGCGGGGGTGGCTGTTTTATC
CTCGGCAGGGAGCGTTTCGC

Downstream 100 bases:

>100_bases
CTTCGAGGTGCAGGTAGGCAGCAAGTGAACGGATCCTGATGCGCTGGCTTAAGCCAGTGATTCCGGTAGGCGAATACCGT
TGACCTCCCTACCACATTCA

Product: chorismate pyruvate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRDALGEEAEHLPVSQRYWLREI
VLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYLFSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFL
PASPLYTHCDSIPK

Sequences:

>Translated_174_residues
MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRDALGEEAEHLPVSQRYWLREI
VLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYLFSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFL
PASPLYTHCDSIPK
>Mature_174_residues
MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRDALGEEAEHLPVSQRYWLREI
VLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYLFSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFL
PASPLYTHCDSIPK

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=158, Percent_Identity=55.6962025316456, Blast_Score=170, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_YERP3 (A7FNA0)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402728.1
- ProteinModelPortal:   A7FNA0
- SMR:   A7FNA0
- STRING:   A7FNA0
- GeneID:   5384844
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3774
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   PLGELLY
- ProtClustDB:   PRK11655
- BioCyc:   YPSE349747:YPSIP31758_3774-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 19916; Mature: 19916

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: BINDING 36-36 BINDING 78-78 BINDING 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRD
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEHH
ALGEEAEHLPVSQRYWLREIVLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYL
HHCCHHHHCCCHHHHHHHHHHHHCCCCCHHHCCCCCCHHHCCCCCHHHHHHCCCCHHHHH
FSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFLPASPLYTHCDSIPK
HCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEHHCCCCHHHHHHCCCCC
>Mature Secondary Structure
MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRD
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEHH
ALGEEAEHLPVSQRYWLREIVLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYL
HHCCHHHHCCCHHHHHHHHHHHHCCCCCHHHCCCCCCHHHCCCCCHHHHHHCCCCHHHHH
FSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFLPASPLYTHCDSIPK
HCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEHHCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA