Click here to switch to the map view.

The map label for this gene is ubiA [H]

Identifier: 218927517

GI number: 218927517

Start: 317386

End: 318252

Strand: Direct

Name: ubiA [H]

Synonym: YPO0311

Alternate gene names: 218927517

Gene position: 317386-318252 (Clockwise)

Preceding gene: 218927516

Following gene: 218927519

Centisome position: 6.82

GC content: 48.44

Gene sequence:

>867_bases
TTGAAGGGAAGTACTGTTCATACCAAATGGCAGGCTTATTGCCGTTTGATGCGTATTGACAAACCGATTGGCTCACTGCT
GCTGCTGTGGCCAACATTGTGGGCATTGTGGTTAGCAGGGAGAGGCATCCCCGAGGCCAAAATACTGGTCGTTTTTGTAC
TGGGGGTCTTTTTCATGCGTGCGGCAGGGTGTGTCGTCAATGATTATGCTGACCGCCATATTGATGGTTTTGTCAAACGC
ACCGCATCCCGGCCACTGCCTAGCGGCACTATCAGTGAGAAAGAGAGCAAAATTCTATTTGTGGTATTGATATTGCTCTC
TTTTGGTTTGGTATTGACCCTCAATAGCATGACGATATGGCTGTCACTGGCCGCATTGGCACTGGCTTGGATCTATCCAT
TTATGAAGCGGGTGACTCATCTGCCGCAGGTGGTATTAGGCGCAGCATTTGGTTGGTCTATTCCGATGGGGTTTGCCGCC
GTTAGCGAAAGCTTGCCGCTGGTCTGCTGGCTACTGTTGCTGGCAAATATCTGCTGGACCGTGGCCTATGACACTCAATA
CGCCATGGTTGATCGTGACGATGACCTAAGAATTGGGGTTAAATCTACGGCGATTCTGTTTGGTCAACATGACAAATTGA
TTATCGGCTTGCTGCAACTGGCGACGTTATTATTAATGGTGGCCATTGGCTGGCTAATGAATCTGGGCGGTGCATTTTAT
TGGTCAATCCTTCTCGCCGGTGCTCTGTTTACTCATCAACAGAAAATGATCGCCCAGCGTGAGCGTGAGCCGTGTTTTCG
TGCGTTTTTGAACAATAATTACGTGGGGTTGGTTTTGTTTCTCGGGATATTGATCAGTTACTGGTAA

Upstream 100 bases:

>100_bases
GTAGGCGAATACCGTTGACCTCCCTACCACATTCAAGATGAAAAGGGTATATCAGGTTTAAGCTAGCTGATTCCGTCGTT
AGATTCTGGAGACTGATCAA

Downstream 100 bases:

>100_bases
CCCGCTTTTACTGAGGGTTAGCGATGACTGAGTATGAGCGCAGAGTCCTCTCACCAAGATACCGAGTTCTCACCAAGGTA
ATGGTAAAAAATGGCCGGAT

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKR
TASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAA
VSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW

Sequences:

>Translated_288_residues
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKR
TASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAA
VSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW
>Mature_288_residues
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKR
TASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAA
VSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=37.6344086021505, Blast_Score=183, Evalue=2e-46,
Organism=Escherichia coli, GI1790473, Length=288, Percent_Identity=73.6111111111111, Blast_Score=417, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17553718, Length=282, Percent_Identity=35.4609929078014, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI32565247, Length=279, Percent_Identity=35.1254480286738, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17553720, Length=248, Percent_Identity=34.2741935483871, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32565245, Length=139, Percent_Identity=41.0071942446043, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=40.5797101449275, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=296, Percent_Identity=30.4054054054054, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21355567, Length=278, Percent_Identity=39.568345323741, Blast_Score=198, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32280; Mature: 32280

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMR
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AAGCVVNDYADRHIDGFVKRTASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIW
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAAVSESLPLVCWLLLLANICWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
HHCCCEEEEECCCCCCEEEEHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMR
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AAGCVVNDYADRHIDGFVKRTASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIW
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAAVSESLPLVCWLLLLANICWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
HHCCCEEEEECCCCCCEEEEHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA