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The map label for this gene is ubiE [C]

Identifier: 159184844

GI number: 159184844

Start: 1611335

End: 1612198

Strand: Direct

Name: ubiE [C]

Synonym: Atu1625

Alternate gene names: 159184844

Gene position: 1611335-1612198 (Clockwise)

Preceding gene: 159184843

Following gene: 15888939

Centisome position: 56.71

GC content: 65.97

Gene sequence:

>864_bases
ATGGCACAACAAAATGCGGAGCATATTGCCGACTGGAGAGGCCAAAGCGGGGAGCGCTGGGCCGCCTACCAGGCCCGGCT
CGATGCCATGATGGCGCCATTCGGCCAAGCTGCGATCGAAGCCGCCGCGCCCACTACCGGCGAACGCGTACTGGACGTCG
GCTGCGGCGCGGGGGCGTCCAGCCGAGATCTGGCCGCTCGCGTCGGCGCGGAGGGCCATGTGCTGGGCGTGGACATATCC
GAACCGCTGATCGAGAGAGCCCGCGCCCTCGCGCCACAGGATATGTCGGTCGTGTTCCGGGTAACCGACGCCAGCAGGGC
CGAGTTGCCCGACGGCGCGTTCGACATCCTGTTCTCACGTTTCGGGGTGATGTTCTTCAACGATCCGACAGGGGCGTTCG
CCCATATGCGCCGTGCGCTCAAGCCGGGCGGGCGGGCCGCTTTTGTCTGCTGGCGCGGCGTGACTGAGAACGATTGGATG
CGGTTGCCGATGGGCGCGATGAAGGGCATCCTCCCATCGATGACGCCGCCTGGTCCGGAAGCCCCCGGCCCGTTCTCGTT
TGGCGACCAGGAGCGTGTGGAGCGCATCCTGACGAAGGCAGGGTTCACCGATATCGCTATCGAGCCTTTCGATGCTTCAG
TCTCGTTTGGCGAGGGCGCAACACGGGACGCGGCGCTCGATGACGCAGTGAACATGACACTTGAGGTCGGCCCGTTGTCG
CGGGTGCTCGCTGATCAGCCCGACGACATACGCGACCGCGCCTCGGTTGCGGTTCGTGCCGCTTTGTCGGGATGCCCCGG
TGAGCGGTCGGTGATGATCAACGGCGCGACATGGATCGTCACCGCGCGCAATCCCGCAAGCTGA

Upstream 100 bases:

>100_bases
GCCGGTCGGCCGTCGCCATGTTCATGGCCGCGCACGGTGGCGACGACCACGTGTGCGCACAGCCTGGTTAAGAACGGATC
GGAAAAGAAAGGATGTGGAC

Downstream 100 bases:

>100_bases
CAGGGATTAACAGTCGGCAGGCAGAATGCGGCGCGGGTCTCTCGGAGACAATTGGCGTCACGACGATAAATAAGGGAGGC
CGGCAAGAAAGCCGGCCATG

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; Methyltransferase UbiE/COQ5 Family; UbiE/COQ5 Methyltransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Protein; UbiE/COQ5 Family Methlytransferase; S-Adenosyl-L-Methionine-Dependent Methyltransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase UbiE; Methlytransferase UbiE/COQ5 Family Protein; Demethylmenaquinone Methyltransferase; UbiE/COQ5 Family Methyltransferase; Menaquinone Biosynthesis Methyltransferase UbiE; Aklanonic Acid Methyl Transferase; Sterol-C-Methyltransferase; Delta(24)-Sterol C-Methyltransferase; Methyltransferase Domain-Containing Protein; Cyclopropane-Fatty-Acyl-Phospholipid Synthase; Methyltransferase S-Adenosyl-L-Methionine-MTase Protein; UbiE/COQ5 Methyltransferase Family; Methyltransferase Domain Family; Menaquinone Biosynthesis Methyltransferase; Sam Dependent Methyltransferase

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MAQQNAEHIADWRGQSGERWAAYQARLDAMMAPFGQAAIEAAAPTTGERVLDVGCGAGASSRDLAARVGAEGHVLGVDIS
EPLIERARALAPQDMSVVFRVTDASRAELPDGAFDILFSRFGVMFFNDPTGAFAHMRRALKPGGRAAFVCWRGVTENDWM
RLPMGAMKGILPSMTPPGPEAPGPFSFGDQERVERILTKAGFTDIAIEPFDASVSFGEGATRDAALDDAVNMTLEVGPLS
RVLADQPDDIRDRASVAVRAALSGCPGERSVMINGATWIVTARNPAS

Sequences:

>Translated_287_residues
MAQQNAEHIADWRGQSGERWAAYQARLDAMMAPFGQAAIEAAAPTTGERVLDVGCGAGASSRDLAARVGAEGHVLGVDIS
EPLIERARALAPQDMSVVFRVTDASRAELPDGAFDILFSRFGVMFFNDPTGAFAHMRRALKPGGRAAFVCWRGVTENDWM
RLPMGAMKGILPSMTPPGPEAPGPFSFGDQERVERILTKAGFTDIAIEPFDASVSFGEGATRDAALDDAVNMTLEVGPLS
RVLADQPDDIRDRASVAVRAALSGCPGERSVMINGATWIVTARNPAS
>Mature_286_residues
AQQNAEHIADWRGQSGERWAAYQARLDAMMAPFGQAAIEAAAPTTGERVLDVGCGAGASSRDLAARVGAEGHVLGVDISE
PLIERARALAPQDMSVVFRVTDASRAELPDGAFDILFSRFGVMFFNDPTGAFAHMRRALKPGGRAAFVCWRGVTENDWMR
LPMGAMKGILPSMTPPGPEAPGPFSFGDQERVERILTKAGFTDIAIEPFDASVSFGEGATRDAALDDAVNMTLEVGPLSR
VLADQPDDIRDRASVAVRAALSGCPGERSVMINGATWIVTARNPAS

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30533; Mature: 30402

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQQNAEHIADWRGQSGERWAAYQARLDAMMAPFGQAAIEAAAPTTGERVLDVGCGAGAS
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCCCCC
SRDLAARVGAEGHVLGVDISEPLIERARALAPQDMSVVFRVTDASRAELPDGAFDILFSR
CHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
FGVMFFNDPTGAFAHMRRALKPGGRAAFVCWRGVTENDWMRLPMGAMKGILPSMTPPGPE
CCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECCHHHHHHCCCCCCCCCCC
APGPFSFGDQERVERILTKAGFTDIAIEPFDASVSFGEGATRDAALDDAVNMTLEVGPLS
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCCCHHHHHHHCCEEEECCHH
RVLADQPDDIRDRASVAVRAALSGCPGERSVMINGATWIVTARNPAS
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECEEEEEECCCCCC
>Mature Secondary Structure 
AQQNAEHIADWRGQSGERWAAYQARLDAMMAPFGQAAIEAAAPTTGERVLDVGCGAGAS
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCCCCC
SRDLAARVGAEGHVLGVDISEPLIERARALAPQDMSVVFRVTDASRAELPDGAFDILFSR
CHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
FGVMFFNDPTGAFAHMRRALKPGGRAAFVCWRGVTENDWMRLPMGAMKGILPSMTPPGPE
CCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECCHHHHHHCCCCCCCCCCC
APGPFSFGDQERVERILTKAGFTDIAIEPFDASVSFGEGATRDAALDDAVNMTLEVGPLS
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCCCHHHHHHHCCEEEECCHH
RVLADQPDDIRDRASVAVRAALSGCPGERSVMINGATWIVTARNPAS
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA