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The map label for this gene is galE [C]

Identifier: 15888939

GI number: 15888939

Start: 1612798

End: 1613688

Strand: Direct

Name: galE [C]

Synonym: Atu1626

Alternate gene names: 15888939

Gene position: 1612798-1613688 (Clockwise)

Preceding gene: 159184844

Following gene: 15888942

Centisome position: 56.76

GC content: 63.08

Gene sequence:

>891_bases
ATGCGGATAGTGCTGACGGGCAGCTCCGGTCGGGTCGGCCGCGCGATTTTCAGTGCCCTCGCCGGCCGGCATGATGTCAC
TGGCATAGACCGCTCCCCCTTTTCCACCACCCATATCGTCGACGATTTCGCGGACGAGTCGCTGCTGCGGAGAGCTTTTG
AGCGAGCGGATGCGGTAATTCATACGGCGGCCCTTCATGCTCCGCATGTTGGTTGCGTTCCGAATGCCGAATTCCAGCGC
ATCAATGTCGATGGAGCCCGCATGGTGGCGGAAGCGGCGATGGCGACCGGCGTGCCACGGCTGGTCTTCACCAGCACCAC
GGCACTCTACGGACACGCTGTTTCTTCGGGGTCCTGCACCTTCATCGATGAAGATACGCCGCCCCAGCCAAAAAGTATCT
ATCACCGCACGAAGCTAGAAGCCGAGCATCTGCTAGAGGAAATGGCCGGACCGCACCTCGCTGTGCGCGTGCTCCGCATG
TCACGCAGTTTCCCGGAGCCCGCCGACGTGATGGCAGCATATCGGCAACATCGCGGCGTCGATATCCGTGATGTCGCCGA
CGCTCATGTGCTGGCGCTGGGCAATGCGGGAGAAGACTTCCAGCGCTATATCGTATCGGCCTCCACCCCGTTTTTCGCTG
ATGACTGCGACGCCCTCGCCAAGGATGCGCCCTCCGTTCTCCGCCAGCGGACCCCGGGCCTCACAGACGCTTTCGCACAG
GAAGGCTGGGCGCTGCCGACGACCATCGACCGCGTCTATTCACCCGCCCGCGCCGTAGAGGGGCTTGGCTGGACATCCCA
GTTCGGCTCCGATGAAGTGCTGGCCCAGCTTGCCCGGCGCAGCCTGGAAGTGCTGCCGGCCGGCGCCAATATCGGCAGGA
AATCCGAATAG

Upstream 100 bases:

>100_bases
GAATGGCCAGTATTCGGATACATTGCTCATCTGATCATCCGGATGAACCCTTGAAAGGCGGCGCCAGGCGCTGCTTTTCT
GTTGATGCGGAGGGAACATC

Downstream 100 bases:

>100_bases
GCCGGCCCTATGCCGCCGCATCCTCTCGCACTTCCAGAATGCGGTCGATCAGCCCCCATTCCAGAGCCTCCTGCACCGTC
ATGAAGCGGTCGCGATCCAT

Product: NAD dependent epimerase/dehydratase family protein

Products: UDPgalactose

Alternate protein names: UDP-Glucose 4-Epimerase Protein; UDP-Glucose 4-Epimerase; Nucleoside-Diphosphate-Sugar Epimerase; Oxidoreductase Protein; 3-Beta Hydroxysteroid Dehydrogenase/Isomerase; Oxidoreductase; NAD Dependent Epimerase/Dehydratase Family Protein; Sugar Epimerase/Dehydratase Homolog; 3-Beta Hydroxysteroid Dehydrogenase/Isomerase Family; Nucleoside-Diphosphate-Sugar Epimerases; UDP-Galactose 4-Epimerase; Nucleotide Sugar Epimerase/Dehydratase; Vitamin K Epoxide Reductase; DTDP-Glucose-4 6-Dehydratase; NAD-Dependent Epimerase/Dehydratase Family Protein; DTDP-Glucose-4 6-Dehydratase-Related Protein

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MRIVLTGSSGRVGRAIFSALAGRHDVTGIDRSPFSTTHIVDDFADESLLRRAFERADAVIHTAALHAPHVGCVPNAEFQR
INVDGARMVAEAAMATGVPRLVFTSTTALYGHAVSSGSCTFIDEDTPPQPKSIYHRTKLEAEHLLEEMAGPHLAVRVLRM
SRSFPEPADVMAAYRQHRGVDIRDVADAHVLALGNAGEDFQRYIVSASTPFFADDCDALAKDAPSVLRQRTPGLTDAFAQ
EGWALPTTIDRVYSPARAVEGLGWTSQFGSDEVLAQLARRSLEVLPAGANIGRKSE

Sequences:

>Translated_296_residues
MRIVLTGSSGRVGRAIFSALAGRHDVTGIDRSPFSTTHIVDDFADESLLRRAFERADAVIHTAALHAPHVGCVPNAEFQR
INVDGARMVAEAAMATGVPRLVFTSTTALYGHAVSSGSCTFIDEDTPPQPKSIYHRTKLEAEHLLEEMAGPHLAVRVLRM
SRSFPEPADVMAAYRQHRGVDIRDVADAHVLALGNAGEDFQRYIVSASTPFFADDCDALAKDAPSVLRQRTPGLTDAFAQ
EGWALPTTIDRVYSPARAVEGLGWTSQFGSDEVLAQLARRSLEVLPAGANIGRKSE
>Mature_296_residues
MRIVLTGSSGRVGRAIFSALAGRHDVTGIDRSPFSTTHIVDDFADESLLRRAFERADAVIHTAALHAPHVGCVPNAEFQR
INVDGARMVAEAAMATGVPRLVFTSTTALYGHAVSSGSCTFIDEDTPPQPKSIYHRTKLEAEHLLEEMAGPHLAVRVLRM
SRSFPEPADVMAAYRQHRGVDIRDVADAHVLALGNAGEDFQRYIVSASTPFFADDCDALAKDAPSVLRQRTPGLTDAFAQ
EGWALPTTIDRVYSPARAVEGLGWTSQFGSDEVLAQLARRSLEVLPAGANIGRKSE

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.1.3.2

Molecular weight: Translated: 31988; Mature: 31988

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVLTGSSGRVGRAIFSALAGRHDVTGIDRSPFSTTHIVDDFADESLLRRAFERADAVI
CEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HTAALHAPHVGCVPNAEFQRINVDGARMVAEAAMATGVPRLVFTSTTALYGHAVSSGSCT
HHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEE
FIDEDTPPQPKSIYHRTKLEAEHLLEEMAGPHLAVRVLRMSRSFPEPADVMAAYRQHRGV
EECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
DIRDVADAHVLALGNAGEDFQRYIVSASTPFFADDCDALAKDAPSVLRQRTPGLTDAFAQ
CHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
EGWALPTTIDRVYSPARAVEGLGWTSQFGSDEVLAQLARRSLEVLPAGANIGRKSE
CCCCCCHHHHHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCC
>Mature Secondary Structure
MRIVLTGSSGRVGRAIFSALAGRHDVTGIDRSPFSTTHIVDDFADESLLRRAFERADAVI
CEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HTAALHAPHVGCVPNAEFQRINVDGARMVAEAAMATGVPRLVFTSTTALYGHAVSSGSCT
HHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEE
FIDEDTPPQPKSIYHRTKLEAEHLLEEMAGPHLAVRVLRMSRSFPEPADVMAAYRQHRGV
EECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
DIRDVADAHVLALGNAGEDFQRYIVSASTPFFADDCDALAKDAPSVLRQRTPGLTDAFAQ
CHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
EGWALPTTIDRVYSPARAVEGLGWTSQFGSDEVLAQLARRSLEVLPAGANIGRKSE
CCCCCCHHHHHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDP-glucose

Specific reaction: UDP-glucose = UDP-galactose

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA