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The map label for this gene is aapQ [H]

Identifier: 159184824

GI number: 159184824

Start: 1563516

End: 1564712

Strand: Direct

Name: aapQ [H]

Synonym: Atu1578

Alternate gene names: 159184824

Gene position: 1563516-1564712 (Clockwise)

Preceding gene: 159184823

Following gene: 15888896

Centisome position: 55.02

GC content: 57.31

Gene sequence:

>1197_bases
ATGGCAGGCAACGCGGTCAGTTCGCAACGATCGCGCGCGCAAAGCGCGTCGTCACTTATCTACGATCCACGCATTCGCGG
CATTTTCTATCAGGTCCTGACAGTCGTCATCCTGACCGCCTTCGTCTGGGTCATCGTGACGAATACGATCACCAATCTTC
AACGGTCAAACATTTCGTCCGGCTTTGGCTTCCTCGATGGAAGAGCCGGTTTCGATATCGGCCAGTCGTTGATCGCTTAT
ACGAGCGACTCGACCTATGGCCGGGCTTTGATCGTTGGTATTCTCAACACGATCCAGGTCGCATTTTTCGGCATCATCGC
CGCCTCGATCATCGGTTTTATCGTCGGTATCGCGCGGTTGTCCAATAACTGGCTGATCTCGAAGCTCGCGCAGGCCTATG
TGGAAATCTTCCGCAACATCCCGCCGCTGCTCGTCATCTTCTTCTGGTACAAGGGCGTCATCTCGGTTCTGCCGCAGGCG
CGCGATTCGCTGGAGCTGCCGCTTGGAAGCTATCTCAACAATCGCGGCTTCTTTTTTCCCAAACCACTCTGGGGAGAAGG
CACCTGGCTGATACCGCTCGCCTTTCTGGTCGCAATCGTCATCAGTTTTTTCGTTTATCGCTGGGCAAAGGCGCGACAGG
AACAAACTGGCCAGCAATTCCGCACCGGTATCACGGCCGCACTTCTCATCATCGGCCTTCCGGCCGCGACATTTCTGGCG
CTCGGTTCACCGCTGACATTCGATTACCCGATTGCCGGACGGTTCAACCTTTCTGGCGGCTCAGTCGTGGCACCGGAATT
CATGTCGCTGTTCCTGGCCCTGTCCTTCTACACCGCTTCCTTCATCGCCGAGATCGTTCGCGGCGGCATCAAGGCCGTGG
CGAAGGGGCAGACGGAGGCTGCGGACGCGCTAGGACTTCGCTCGAGCACCACGACGCGTTTGATCGTCGTGCCGCAGGCA
ATGCGCATCATCATCCCGCCACTCACAAGCCAGTTTCTCAACCTGACGAAAAACTCCTCGCTTGCAGTCGCTGTCGGTTT
CGCCGACATCGTCTCCGTCGGCGGCACGATCCTGAACCAGACGGGTCAGGCGGTTGAAGTCGTCGCGATCTGGCTGGTCA
TTTATCTCTCGCTGTCCCTGCTCACGGCCCTGGTCATGAACTGGTTCAACGCGAAAATGGCCCTGGTGGAGAGATAA

Upstream 100 bases:

>100_bases
TCATCGGCTAGATCACGACGGGAGGCTGGGCAACGCCCGGCCTCCATTTTAGAATTATATAAATAAGCTCGCAAAGAGCA
TATAAAAGGGAAAGGTGCCT

Downstream 100 bases:

>100_bases
CGATGACAATAAGCAATCACGCTTTCGTGCGACAGACCATCGAGGACGCCAGACCCGCGCCCTCGAGTGCGGTCGGCTTC
GGCCATTGGCTGCGCACCAA

Product: ABC transporter, membrane spanning protein (amino acid)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAGNAVSSQRSRAQSASSLIYDPRIRGIFYQVLTVVILTAFVWVIVTNTITNLQRSNISSGFGFLDGRAGFDIGQSLIAY
TSDSTYGRALIVGILNTIQVAFFGIIAASIIGFIVGIARLSNNWLISKLAQAYVEIFRNIPPLLVIFFWYKGVISVLPQA
RDSLELPLGSYLNNRGFFFPKPLWGEGTWLIPLAFLVAIVISFFVYRWAKARQEQTGQQFRTGITAALLIIGLPAATFLA
LGSPLTFDYPIAGRFNLSGGSVVAPEFMSLFLALSFYTASFIAEIVRGGIKAVAKGQTEAADALGLRSSTTTRLIVVPQA
MRIIIPPLTSQFLNLTKNSSLAVAVGFADIVSVGGTILNQTGQAVEVVAIWLVIYLSLSLLTALVMNWFNAKMALVER

Sequences:

>Translated_398_residues
MAGNAVSSQRSRAQSASSLIYDPRIRGIFYQVLTVVILTAFVWVIVTNTITNLQRSNISSGFGFLDGRAGFDIGQSLIAY
TSDSTYGRALIVGILNTIQVAFFGIIAASIIGFIVGIARLSNNWLISKLAQAYVEIFRNIPPLLVIFFWYKGVISVLPQA
RDSLELPLGSYLNNRGFFFPKPLWGEGTWLIPLAFLVAIVISFFVYRWAKARQEQTGQQFRTGITAALLIIGLPAATFLA
LGSPLTFDYPIAGRFNLSGGSVVAPEFMSLFLALSFYTASFIAEIVRGGIKAVAKGQTEAADALGLRSSTTTRLIVVPQA
MRIIIPPLTSQFLNLTKNSSLAVAVGFADIVSVGGTILNQTGQAVEVVAIWLVIYLSLSLLTALVMNWFNAKMALVER
>Mature_397_residues
AGNAVSSQRSRAQSASSLIYDPRIRGIFYQVLTVVILTAFVWVIVTNTITNLQRSNISSGFGFLDGRAGFDIGQSLIAYT
SDSTYGRALIVGILNTIQVAFFGIIAASIIGFIVGIARLSNNWLISKLAQAYVEIFRNIPPLLVIFFWYKGVISVLPQAR
DSLELPLGSYLNNRGFFFPKPLWGEGTWLIPLAFLVAIVISFFVYRWAKARQEQTGQQFRTGITAALLIIGLPAATFLAL
GSPLTFDYPIAGRFNLSGGSVVAPEFMSLFLALSFYTASFIAEIVRGGIKAVAKGQTEAADALGLRSSTTTRLIVVPQAM
RIIIPPLTSQFLNLTKNSSLAVAVGFADIVSVGGTILNQTGQAVEVVAIWLVIYLSLSLLTALVMNWFNAKMALVER

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=394, Percent_Identity=48.9847715736041, Blast_Score=350, Evalue=7e-98,
Organism=Escherichia coli, GI1786874, Length=132, Percent_Identity=36.3636363636364, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786873, Length=129, Percent_Identity=31.0077519379845, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788226, Length=133, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787030, Length=119, Percent_Identity=31.0924369747899, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082239, Length=76, Percent_Identity=39.4736842105263, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787087, Length=136, Percent_Identity=30.1470588235294, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43184; Mature: 43053

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGNAVSSQRSRAQSASSLIYDPRIRGIFYQVLTVVILTAFVWVIVTNTITNLQRSNISS
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GFGFLDGRAGFDIGQSLIAYTSDSTYGRALIVGILNTIQVAFFGIIAASIIGFIVGIARL
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNNWLISKLAQAYVEIFRNIPPLLVIFFWYKGVISVLPQARDSLELPLGSYLNNRGFFFP
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHCCCCCCCC
KPLWGEGTWLIPLAFLVAIVISFFVYRWAKARQEQTGQQFRTGITAALLIIGLPAATFLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSPLTFDYPIAGRFNLSGGSVVAPEFMSLFLALSFYTASFIAEIVRGGIKAVAKGQTEA
CCCCCEECCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ADALGLRSSTTTRLIVVPQAMRIIIPPLTSQFLNLTKNSSLAVAVGFADIVSVGGTILNQ
HHHHCCCCCCCEEEEEECCHHHHEECCHHHHHHHHCCCCCEEEEEHHHHHHHHCHHHHHC
TGQAVEVVAIWLVIYLSLSLLTALVMNWFNAKMALVER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]