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The map label for this gene is aapM [H]

Identifier: 15888896

GI number: 15888896

Start: 1564715

End: 1565872

Strand: Direct

Name: aapM [H]

Synonym: Atu1579

Alternate gene names: 15888896

Gene position: 1564715-1565872 (Clockwise)

Preceding gene: 159184824

Following gene: 15888897

Centisome position: 55.06

GC content: 59.15

Gene sequence:

>1158_bases
ATGACAATAAGCAATCACGCTTTCGTGCGACAGACCATCGAGGACGCCAGACCCGCGCCCTCGAGTGCGGTCGGCTTCGG
CCATTGGCTGCGCACCAAACTCTTCGCCACACCCAAGGACACTGTCCTGACGGTGATCGCCCTTGCCCTGCTCGCCTATC
TGGTTCCGCCCATCATCAAGTGGCTCTTCATCGATGCGGTGTGGACCGGCAGCGATCGTTTCGCCTGCCTGACCGTTTCG
CAAGGTGGCGCACTACCGGATGGCCAGTCCGGCGCGTGCTGGGCTTTCGTGTCCGCCAAGCTCGGGCAGTTCGTCTTTGG
CCGCTACCCGATCGATGAGCGCTGGCGTCCCATCCTTGTGATGGTGACATTTGCCATCCTGCTCGTGCCCATGCTTATCC
CCAAAGCGCCGTTCAAGCGCCTCAACGCGCTGGCGCTTTTCATCATCCTGCCTTTCATTGCGTTTTTCCTGCTTATCGGC
GGCGTCTTCGGCCTGCCTAAGGTTGAAACGCAGCTCTGGGGCGGCCTCATGGTGACGCTCATCCTGTCCTTCTTCGGGAT
CACGGTGTCGTTGCCCTTCGGCATTCTTCTGGCGCTCGGGCGGCGATCGAACCTGCCTGTCATCAAGATGCTCTGCGTGC
TCTTCATCGAAGTCATCAGAGGCATCCCGCTGATCACCGTCCTGTTCTTCGCCAGCATCATGTTGCCGTTGTTCCTGCCC
GACGGCTGGACCTTCGACAAGTTCCTGCGCGCGCTTGTCGGTGTGTCGCTGTTCTCGTCTGCCTATATGGCGGAGGTGAT
CCGCGGCGGTCTGCAGGCCATTCCCAAGGGGCAATATGAAGGTGCTGACTCACTCGGCCTGAACTACTGGCAGAAGACGA
GGCTGATCGTGCTGCCGCAGGCGCTGAAGCTCGTCATTCCGGGCATCGTCAACACCTTCATCGGGCTGTTCAAGGACACG
TCGCTGGTCTCGATCATCGGCATGTTCGACCTGCTCGGTATTGTCACACTCAACCAAGCGGATGCGAACTGGGCGACGCC
GGTCACCGCCATGACTGGCTATATTTTCGCAGGCTTCGTATTCTGGATATTCTGCTTCGGCATGTCGCGTTATTCGCTGT
TCATGGAACGGCACCTCGACACCGGGCATAAACGATAA

Upstream 100 bases:

>100_bases
TCGTCGCGATCTGGCTGGTCATTTATCTCTCGCTGTCCCTGCTCACGGCCCTGGTCATGAACTGGTTCAACGCGAAAATG
GCCCTGGTGGAGAGATAACG

Downstream 100 bases:

>100_bases
GGGACGCTCAAAATGGCAGAAAACCAAGCAAAAAAACTGGCCGTCTCGACAACGGACGTCGCAATCGAAATCACCGGCAT
GAACAAGTGGTATGGCGATT

Product: ABC transporter, membrane spanning protein (amino acid)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTISNHAFVRQTIEDARPAPSSAVGFGHWLRTKLFATPKDTVLTVIALALLAYLVPPIIKWLFIDAVWTGSDRFACLTVS
QGGALPDGQSGACWAFVSAKLGQFVFGRYPIDERWRPILVMVTFAILLVPMLIPKAPFKRLNALALFIILPFIAFFLLIG
GVFGLPKVETQLWGGLMVTLILSFFGITVSLPFGILLALGRRSNLPVIKMLCVLFIEVIRGIPLITVLFFASIMLPLFLP
DGWTFDKFLRALVGVSLFSSAYMAEVIRGGLQAIPKGQYEGADSLGLNYWQKTRLIVLPQALKLVIPGIVNTFIGLFKDT
SLVSIIGMFDLLGIVTLNQADANWATPVTAMTGYIFAGFVFWIFCFGMSRYSLFMERHLDTGHKR

Sequences:

>Translated_385_residues
MTISNHAFVRQTIEDARPAPSSAVGFGHWLRTKLFATPKDTVLTVIALALLAYLVPPIIKWLFIDAVWTGSDRFACLTVS
QGGALPDGQSGACWAFVSAKLGQFVFGRYPIDERWRPILVMVTFAILLVPMLIPKAPFKRLNALALFIILPFIAFFLLIG
GVFGLPKVETQLWGGLMVTLILSFFGITVSLPFGILLALGRRSNLPVIKMLCVLFIEVIRGIPLITVLFFASIMLPLFLP
DGWTFDKFLRALVGVSLFSSAYMAEVIRGGLQAIPKGQYEGADSLGLNYWQKTRLIVLPQALKLVIPGIVNTFIGLFKDT
SLVSIIGMFDLLGIVTLNQADANWATPVTAMTGYIFAGFVFWIFCFGMSRYSLFMERHLDTGHKR
>Mature_384_residues
TISNHAFVRQTIEDARPAPSSAVGFGHWLRTKLFATPKDTVLTVIALALLAYLVPPIIKWLFIDAVWTGSDRFACLTVSQ
GGALPDGQSGACWAFVSAKLGQFVFGRYPIDERWRPILVMVTFAILLVPMLIPKAPFKRLNALALFIILPFIAFFLLIGG
VFGLPKVETQLWGGLMVTLILSFFGITVSLPFGILLALGRRSNLPVIKMLCVLFIEVIRGIPLITVLFFASIMLPLFLPD
GWTFDKFLRALVGVSLFSSAYMAEVIRGGLQAIPKGQYEGADSLGLNYWQKTRLIVLPQALKLVIPGIVNTFIGLFKDTS
LVSIIGMFDLLGIVTLNQADANWATPVTAMTGYIFAGFVFWIFCFGMSRYSLFMERHLDTGHKR

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=367, Percent_Identity=49.0463215258856, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=34.5794392523364, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786873, Length=213, Percent_Identity=30.5164319248826, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787030, Length=157, Percent_Identity=35.6687898089172, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786874, Length=170, Percent_Identity=27.0588235294118, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI48994930, Length=128, Percent_Identity=32.03125, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787087, Length=155, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788645, Length=185, Percent_Identity=30.8108108108108, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788646, Length=219, Percent_Identity=26.027397260274, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787086, Length=170, Percent_Identity=27.6470588235294, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 42579; Mature: 42447

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISNHAFVRQTIEDARPAPSSAVGFGHWLRTKLFATPKDTVLTVIALALLAYLVPPIIK
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
WLFIDAVWTGSDRFACLTVSQGGALPDGQSGACWAFVSAKLGQFVFGRYPIDERWRPILV
HHHHHHHEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
MVTFAILLVPMLIPKAPFKRLNALALFIILPFIAFFLLIGGVFGLPKVETQLWGGLMVTL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ILSFFGITVSLPFGILLALGRRSNLPVIKMLCVLFIEVIRGIPLITVLFFASIMLPLFLP
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
DGWTFDKFLRALVGVSLFSSAYMAEVIRGGLQAIPKGQYEGADSLGLNYWQKTRLIVLPQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHCEEEEEHH
ALKLVIPGIVNTFIGLFKDTSLVSIIGMFDLLGIVTLNQADANWATPVTAMTGYIFAGFV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHH
FWIFCFGMSRYSLFMERHLDTGHKR
HHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TISNHAFVRQTIEDARPAPSSAVGFGHWLRTKLFATPKDTVLTVIALALLAYLVPPIIK
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
WLFIDAVWTGSDRFACLTVSQGGALPDGQSGACWAFVSAKLGQFVFGRYPIDERWRPILV
HHHHHHHEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
MVTFAILLVPMLIPKAPFKRLNALALFIILPFIAFFLLIGGVFGLPKVETQLWGGLMVTL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ILSFFGITVSLPFGILLALGRRSNLPVIKMLCVLFIEVIRGIPLITVLFFASIMLPLFLP
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
DGWTFDKFLRALVGVSLFSSAYMAEVIRGGLQAIPKGQYEGADSLGLNYWQKTRLIVLPQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHCEEEEEHH
ALKLVIPGIVNTFIGLFKDTSLVSIIGMFDLLGIVTLNQADANWATPVTAMTGYIFAGFV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHH
FWIFCFGMSRYSLFMERHLDTGHKR
HHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]