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The map label for this gene is clc [C]

Identifier: 159184780

GI number: 159184780

Start: 1481706

End: 1483487

Strand: Reverse

Name: clc [C]

Synonym: Atu1493

Alternate gene names: 159184780

Gene position: 1483487-1481706 (Counterclockwise)

Preceding gene: 159184781

Following gene: 15888817

Centisome position: 52.21

GC content: 61.39

Gene sequence:

>1782_bases
ATGTCGACCAAGCCTTTCCGTGCACCGAGTATGGCGAGCTTCTTCGACAATCTGCGCGCCAGCCGGCTGCGGGCCATGTT
CCGGCGCGGCGAACTTGGTCTCGTCGCGCTCGCCGTTCTCATCGGCGTTGCGGCGGGCCTGTTGGTGGCGCTGATCGGGG
CCTTGAGCACGGCGCTGCATATATTGGTCTTCGGTGTGGAGCGGCTGAGCAGCAGCGACCTGTCCGGTCGGATCGTGCTG
TTCGGGCCAATAATCGGCGGCATGCTGCTTGGCCTCATCATCTTCATTCTGTCGAAGACCCGCAAGAAACCCATGATCGA
CCCGATCGAGGCGAATGCTCTACATGGCGGCCGCCTGTCGCTGACCGACAGCATCATCGTTTGCGTGCAGAACATCGTTT
CCAATGGTTTCGGCGCGTCCGTCGGGCTTGAGGCCGGTTATACGCAGATCGCCAGCGGCGTCGCTTCCAAGATCGGCATC
AAACTGAAACTGAGGCGAGGGGACATGCGCATCCTCGTCGGGTGTGGCGCCGCAGGTGCGATCGCCGCGGCCTTCAACGC
GCCTCTCACCGGAGCCTTCTACGCCATCGAACTCATCATCGGCACCTATACCGTGGTGACGCTGGCGCCGCTCATCGTCT
CTGCACTGGTGGCGACCACCGTCATCGGGCTTATCGGCGGGCATGGTCTGTCGATCGATATTGTCGATGCCAGCCGTGTA
ACGCCGGCGGATTATGTGCCCGCTATCTTCCTCGGTGTCGTCTGTGCCGCCATCGGCATCGTGCTGATGCAGGCGGTATC
CTTCATCGAGGAAACGGCACGCAAAAGCGCCATTCCCGGCTGGCTGCGTCCCACGCTTGGCGGCGTGGCGGTGGGTGGGC
TAGCGCTGATTTCGCCGCAGGTTCTCTCGAGCGGCCATGGTGCGCTGCATCTCAACATCGATGCCGAATTGACCATCTAT
GGGCTGGCCGGGCTGTTTATGCTGAAGGCGGCAGCCAGCGCCATTTCCATCGGCTCGAATTTCCGCGGCGGCCTGTTTTT
CGCCTCACTGTTCATGGGCTCGCTGCTCGGCAAGATTTTCGCGCTCTGCGCACCCTATATCGGTTACGGCTCGACGGCTC
CCATCGTTTATGCGGTGATCGGCATGAGTGCCTTTGCCGCCGCGATTATCGGTGGGCCGTTGACGATGACGTTTCTGGCG
CTGGAATTGACCGGCGACTTCCAGATCACGGCGCTTGTGCTGGCCGCTGTCATCACTACCTCGCTGGTGGTGCGCACCAC
CTTCGGTTACTCGTTCGCCACCTGGCGTTTTCACCTGCGCGGCGAGAGCATTCGCAGCGCCCATGATATTGGCTGGATCC
GCGATCTGACGGTGGGCAAGATGATGCGCGCCGACATCCGCAAAGCCAATGTCAGCATGGGGCTTCCGGCCTTCAAGGAG
AAGTTCCCGCTCGGCTCGACGCAGCGGGTGATCATGACCCATGATGACGGGCGTTACGCCGGTATGGTGCTCGTGCCGGA
AATCTATGCCGATCCGATGGACCGCGACCCCAGCAAAATCAGCCTCGAAACCTATCTGCACTACAAGAACGACATCTTGC
TGCCGACCATGAATGCACGGCAGGCCGCGGCCGCCTTCGACGCGGCCGAAAGCGAAGCCCTGGTCGTCGTCAACGACAAG
ATCGAAAACCGGCCCGTCGGCTTGCTTACCGAGAGCCATACGCTGAGGCGTTATAGCGAAGAGCTTGATCTGAGGCGCCG
GGAGGCTTCCGGAGAACTCTAA

Upstream 100 bases:

>100_bases
GCACGTCTCCTAAAACCGCATTCGGGTTTTGGACATGACGCGCTTTGAAACAACCAATTAAAGGCGCATGGCGCTTTGGC
GCCGTCTGAAAAGGAACAGC

Downstream 100 bases:

>100_bases
ATTACATTAGGAATTTTCACCTATTTATTGATATATAGATGTTATTTCGTTTTTCTTCTGCAGATTTCTCCGAAAATTCC
ACAGATGCAACGCTTAATCG

Product: chloride channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MSTKPFRAPSMASFFDNLRASRLRAMFRRGELGLVALAVLIGVAAGLLVALIGALSTALHILVFGVERLSSSDLSGRIVL
FGPIIGGMLLGLIIFILSKTRKKPMIDPIEANALHGGRLSLTDSIIVCVQNIVSNGFGASVGLEAGYTQIASGVASKIGI
KLKLRRGDMRILVGCGAAGAIAAAFNAPLTGAFYAIELIIGTYTVVTLAPLIVSALVATTVIGLIGGHGLSIDIVDASRV
TPADYVPAIFLGVVCAAIGIVLMQAVSFIEETARKSAIPGWLRPTLGGVAVGGLALISPQVLSSGHGALHLNIDAELTIY
GLAGLFMLKAAASAISIGSNFRGGLFFASLFMGSLLGKIFALCAPYIGYGSTAPIVYAVIGMSAFAAAIIGGPLTMTFLA
LELTGDFQITALVLAAVITTSLVVRTTFGYSFATWRFHLRGESIRSAHDIGWIRDLTVGKMMRADIRKANVSMGLPAFKE
KFPLGSTQRVIMTHDDGRYAGMVLVPEIYADPMDRDPSKISLETYLHYKNDILLPTMNARQAAAAFDAAESEALVVVNDK
IENRPVGLLTESHTLRRYSEELDLRRREASGEL

Sequences:

>Translated_593_residues
MSTKPFRAPSMASFFDNLRASRLRAMFRRGELGLVALAVLIGVAAGLLVALIGALSTALHILVFGVERLSSSDLSGRIVL
FGPIIGGMLLGLIIFILSKTRKKPMIDPIEANALHGGRLSLTDSIIVCVQNIVSNGFGASVGLEAGYTQIASGVASKIGI
KLKLRRGDMRILVGCGAAGAIAAAFNAPLTGAFYAIELIIGTYTVVTLAPLIVSALVATTVIGLIGGHGLSIDIVDASRV
TPADYVPAIFLGVVCAAIGIVLMQAVSFIEETARKSAIPGWLRPTLGGVAVGGLALISPQVLSSGHGALHLNIDAELTIY
GLAGLFMLKAAASAISIGSNFRGGLFFASLFMGSLLGKIFALCAPYIGYGSTAPIVYAVIGMSAFAAAIIGGPLTMTFLA
LELTGDFQITALVLAAVITTSLVVRTTFGYSFATWRFHLRGESIRSAHDIGWIRDLTVGKMMRADIRKANVSMGLPAFKE
KFPLGSTQRVIMTHDDGRYAGMVLVPEIYADPMDRDPSKISLETYLHYKNDILLPTMNARQAAAAFDAAESEALVVVNDK
IENRPVGLLTESHTLRRYSEELDLRRREASGEL
>Mature_592_residues
STKPFRAPSMASFFDNLRASRLRAMFRRGELGLVALAVLIGVAAGLLVALIGALSTALHILVFGVERLSSSDLSGRIVLF
GPIIGGMLLGLIIFILSKTRKKPMIDPIEANALHGGRLSLTDSIIVCVQNIVSNGFGASVGLEAGYTQIASGVASKIGIK
LKLRRGDMRILVGCGAAGAIAAAFNAPLTGAFYAIELIIGTYTVVTLAPLIVSALVATTVIGLIGGHGLSIDIVDASRVT
PADYVPAIFLGVVCAAIGIVLMQAVSFIEETARKSAIPGWLRPTLGGVAVGGLALISPQVLSSGHGALHLNIDAELTIYG
LAGLFMLKAAASAISIGSNFRGGLFFASLFMGSLLGKIFALCAPYIGYGSTAPIVYAVIGMSAFAAAIIGGPLTMTFLAL
ELTGDFQITALVLAAVITTSLVVRTTFGYSFATWRFHLRGESIRSAHDIGWIRDLTVGKMMRADIRKANVSMGLPAFKEK
FPLGSTQRVIMTHDDGRYAGMVLVPEIYADPMDRDPSKISLETYLHYKNDILLPTMNARQAAAAFDAAESEALVVVNDKI
ENRPVGLLTESHTLRRYSEELDLRRREASGEL

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081943, Length=408, Percent_Identity=27.9411764705882, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62655; Mature: 62523

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKPFRAPSMASFFDNLRASRLRAMFRRGELGLVALAVLIGVAAGLLVALIGALSTALH
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILVFGVERLSSSDLSGRIVLFGPIIGGMLLGLIIFILSKTRKKPMIDPIEANALHGGRLS
HHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
LTDSIIVCVQNIVSNGFGASVGLEAGYTQIASGVASKIGIKLKLRRGDMRILVGCGAAGA
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCEEEEEECCCHHH
IAAAFNAPLTGAFYAIELIIGTYTVVTLAPLIVSALVATTVIGLIGGHGLSIDIVDASRV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
TPADYVPAIFLGVVCAAIGIVLMQAVSFIEETARKSAIPGWLRPTLGGVAVGGLALISPQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHCHH
VLSSGHGALHLNIDAELTIYGLAGLFMLKAAASAISIGSNFRGGLFFASLFMGSLLGKIF
HHCCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ALCAPYIGYGSTAPIVYAVIGMSAFAAAIIGGPLTMTFLALELTGDFQITALVLAAVITT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHH
SLVVRTTFGYSFATWRFHLRGESIRSAHDIGWIRDLTVGKMMRADIRKANVSMGLPAFKE
HHHHHHHCCCEEEEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KFPLGSTQRVIMTHDDGRYAGMVLVPEIYADPMDRDPSKISLETYLHYKNDILLPTMNAR
HCCCCCCCEEEEEECCCCEEEEEEECHHHCCCCCCCCCCEEEEHEEEECCCEEEECCCCH
QAAAAFDAAESEALVVVNDKIENRPVGLLTESHTLRRYSEELDLRRREASGEL
HHHHHHCCCCCCEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
STKPFRAPSMASFFDNLRASRLRAMFRRGELGLVALAVLIGVAAGLLVALIGALSTALH
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILVFGVERLSSSDLSGRIVLFGPIIGGMLLGLIIFILSKTRKKPMIDPIEANALHGGRLS
HHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
LTDSIIVCVQNIVSNGFGASVGLEAGYTQIASGVASKIGIKLKLRRGDMRILVGCGAAGA
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCEEEEEECCCHHH
IAAAFNAPLTGAFYAIELIIGTYTVVTLAPLIVSALVATTVIGLIGGHGLSIDIVDASRV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
TPADYVPAIFLGVVCAAIGIVLMQAVSFIEETARKSAIPGWLRPTLGGVAVGGLALISPQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHCHH
VLSSGHGALHLNIDAELTIYGLAGLFMLKAAASAISIGSNFRGGLFFASLFMGSLLGKIF
HHCCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ALCAPYIGYGSTAPIVYAVIGMSAFAAAIIGGPLTMTFLALELTGDFQITALVLAAVITT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHH
SLVVRTTFGYSFATWRFHLRGESIRSAHDIGWIRDLTVGKMMRADIRKANVSMGLPAFKE
HHHHHHHCCCEEEEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KFPLGSTQRVIMTHDDGRYAGMVLVPEIYADPMDRDPSKISLETYLHYKNDILLPTMNAR
HCCCCCCCEEEEEECCCCEEEEEEECHHHCCCCCCCCCCEEEEHEEEECCCEEEECCCCH
QAAAAFDAAESEALVVVNDKIENRPVGLLTESHTLRRYSEELDLRRREASGEL
HHHHHHCCCCCCEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]