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The map label for this gene is lipB [H]

Identifier: 159184781

GI number: 159184781

Start: 1483588

End: 1484412

Strand: Reverse

Name: lipB [H]

Synonym: Atu1494

Alternate gene names: 159184781

Gene position: 1484412-1483588 (Counterclockwise)

Preceding gene: 159184782

Following gene: 159184780

Centisome position: 52.24

GC content: 61.21

Gene sequence:

>825_bases
GTGGCAATCTACCGTCGCCGCTTCACGGTTCTCGGTTGCGCGTCGTCGCCCGGCGTGCCGCGCATCAACGGCGACTGGGG
TGCCTGCGACCCTCAAAACCCCAGGAACAGGCGCACGCGCGCGGCCTTCATGGTGGAGCAGATCGGTCCGGATGGCGGCA
AAACCACCGTCGTCATCGACACCGGCCCGGATTTCCGCGAGCAGATGATTGCCGCGAAGGTGCAAGCCGTCGATGCTGTG
CTTTACACCCACGCCCACGCCGACCATCTGCACGGCATCGATGACCTGCGCATCTATTTCGCTCTCCAGAAAAGCCGTAT
TCCGATCTGGGCCGATCCCGTCACCATGGCGCGCATCCGCGACGGTTTTGCCTATTGCCTGGAGACGCCGGCGGGCAGCA
ACTATCCGCCGATCGTCAGGCCGCAGCTTATCGCCGATATCAACGACCCTGTTATCATCGACGGGGCAGGCGGGCCGATC
CCCTTCAAGGTGCATATGCAGCAGCATGGCGACGTGCATTCGCTGGGTTTTCGCATCGGCGACGTTGCCTATTGCACCGA
TGTCAGCGATTTTCCGGCGGAAAGCCTGCCCAAGCTTACCGGCCTCGATGTGCTCGTCATCGATGCCTTGCAGTATCGAT
ATCACCCCAGCCATCTTTCGCTGGAACAGGCGCTCGGCTGGATCGAGGCACTCGCACCCAAACGGGCGATCTTGACCCAC
ATGCACATTCCGCTCGATTATGACACGGTGATGCGTGAGACGCCGGATCATGTTGAACCGGCTTACGACCAGATGCGTTT
CGAGGTTGAGATCGAAGCGCCCTGA

Upstream 100 bases:

>100_bases
AGGTTCTGGCCGAAGTGCATGGTGTTTCCTTCGAGCATATGGCCGAAATCACCACCGAAAACGCCTTTCGTTGCTTTTCC
AAGATGACAAGGGTGTAGGT

Downstream 100 bases:

>100_bases
GCACGTCTCCTAAAACCGCATTCGGGTTTTGGACATGACGCGCTTTGAAACAACCAATTAAAGGCGCATGGCGCTTTGGC
GCCGTCTGAAAAGGAACAGC

Product: metal dependent hydrolase

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MAIYRRRFTVLGCASSPGVPRINGDWGACDPQNPRNRRTRAAFMVEQIGPDGGKTTVVIDTGPDFREQMIAAKVQAVDAV
LYTHAHADHLHGIDDLRIYFALQKSRIPIWADPVTMARIRDGFAYCLETPAGSNYPPIVRPQLIADINDPVIIDGAGGPI
PFKVHMQQHGDVHSLGFRIGDVAYCTDVSDFPAESLPKLTGLDVLVIDALQYRYHPSHLSLEQALGWIEALAPKRAILTH
MHIPLDYDTVMRETPDHVEPAYDQMRFEVEIEAP

Sequences:

>Translated_274_residues
MAIYRRRFTVLGCASSPGVPRINGDWGACDPQNPRNRRTRAAFMVEQIGPDGGKTTVVIDTGPDFREQMIAAKVQAVDAV
LYTHAHADHLHGIDDLRIYFALQKSRIPIWADPVTMARIRDGFAYCLETPAGSNYPPIVRPQLIADINDPVIIDGAGGPI
PFKVHMQQHGDVHSLGFRIGDVAYCTDVSDFPAESLPKLTGLDVLVIDALQYRYHPSHLSLEQALGWIEALAPKRAILTH
MHIPLDYDTVMRETPDHVEPAYDQMRFEVEIEAP
>Mature_273_residues
AIYRRRFTVLGCASSPGVPRINGDWGACDPQNPRNRRTRAAFMVEQIGPDGGKTTVVIDTGPDFREQMIAAKVQAVDAVL
YTHAHADHLHGIDDLRIYFALQKSRIPIWADPVTMARIRDGFAYCLETPAGSNYPPIVRPQLIADINDPVIIDGAGGPIP
FKVHMQQHGDVHSLGFRIGDVAYCTDVSDFPAESLPKLTGLDVLVIDALQYRYHPSHLSLEQALGWIEALAPKRAILTHM
HIPLDYDTVMRETPDHVEPAYDQMRFEVEIEAP

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 30497; Mature: 30366

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYRRRFTVLGCASSPGVPRINGDWGACDPQNPRNRRTRAAFMVEQIGPDGGKTTVVID
CCEEEEEEEEEEECCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
TGPDFREQMIAAKVQAVDAVLYTHAHADHLHGIDDLRIYFALQKSRIPIWADPVTMARIR
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEEEECCCCCEEECCHHHHHHH
DGFAYCLETPAGSNYPPIVRPQLIADINDPVIIDGAGGPIPFKVHMQQHGDVHSLGFRIG
CCCEEEEECCCCCCCCCCCCCHHEECCCCCEEEECCCCCCEEEEEECCCCCEEHHCEEEC
DVAYCTDVSDFPAESLPKLTGLDVLVIDALQYRYHPSHLSLEQALGWIEALAPKRAILTH
CEEEECCCCCCCHHHCCCCCCCCEEEEEHHHHEECCCCCCHHHHHHHHHHHCCHHHHHEE
MHIPLDYDTVMRETPDHVEPAYDQMRFEVEIEAP
EECCCCHHHHHHCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
AIYRRRFTVLGCASSPGVPRINGDWGACDPQNPRNRRTRAAFMVEQIGPDGGKTTVVID
CEEEEEEEEEEECCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
TGPDFREQMIAAKVQAVDAVLYTHAHADHLHGIDDLRIYFALQKSRIPIWADPVTMARIR
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEEEECCCCCEEECCHHHHHHH
DGFAYCLETPAGSNYPPIVRPQLIADINDPVIIDGAGGPIPFKVHMQQHGDVHSLGFRIG
CCCEEEEECCCCCCCCCCCCCHHEECCCCCEEEECCCCCCEEEEEECCCCCEEHHCEEEC
DVAYCTDVSDFPAESLPKLTGLDVLVIDALQYRYHPSHLSLEQALGWIEALAPKRAILTH
CEEEECCCCCCCHHHCCCCCCCCEEEEEHHHHEECCCCCCHHHHHHHHHHHCCHHHHHEE
MHIPLDYDTVMRETPDHVEPAYDQMRFEVEIEAP
EECCCCHHHHHHCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]