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The map label for this gene is mcpA [H]

Identifier: 159184286

GI number: 159184286

Start: 378771

End: 380819

Strand: Direct

Name: mcpA [H]

Synonym: Atu0387

Alternate gene names: 159184286

Gene position: 378771-380819 (Clockwise)

Preceding gene: 15887732

Following gene: 15887737

Centisome position: 13.33

GC content: 61.84

Gene sequence:

>2049_bases
TTGAGAATTCGCGGTCGTATCAATCTACTTGTCGGGCTGATGAGCCTTGTGGCCTGTACCATCGGTGGACTGTCCATCTA
TGCGGTCAGCGAATTCCGGGTCCGCACGGTCGAATATGAAAAGGCGGCGGAGCGCGCCTATAAGGGCGAGGCGCTCAACC
GCTTGGTTACCGCGGTCGTGATGGAGGCGCGCGGGGTCTATGCCGCTGCCGATATCGAAAAGGCGGCGCCCTTTGCGGAC
GGCATCGTCAAGAACCTCGATGCCATGGAGAAGCTGATCGCCACATGGACCCCTCTCGTTCCGGCGGAACAGAAGGCAAC
CTTCGATAATCTCTCCAGCCGCTTCAAGGAGTTCAAGACCTTCCGCCTTGAGACCGCGCGGCTTGCCCGTGAAGCTGGCC
CGCAGGCGGCCAACCAGCAGGGCAACAACGAGGCGAACCGGGCCAACCGCAAAGCCTATCAGGCGGAAATCGACGCCGTC
GTGAAGAACGACATTGCCGAGCTTGAGGCCGTCAAGGCCGGCATCGACGGTTTTGTAACGACAACATTCTGGCTGGTCAT
CACCGTCACCGGCAGTGGCATATTGGCCGGCGCGGCCTTCGGTCTTTATATTGGAGCACGGCAATTGAGTGCGCCGATCC
GCAGGGTTTCGGAAGTGATGAACGCCGTGGCTGACGGAAATCTGGACGCGGATGTGCCCTATCTCGGCCAGAACGACGAG
ATCGGTGAAATGGCGGCGGCTGTTGAAGTCTTCAAAAAGAACGGCCGCGAAGTACGCCGCATGAACGCTCAGGAAACAGC
CATGCGCGCCAAGAGCGACGATCTTCAGGCCGGCATGGCTGTTGTCGTCGATGCTGCGGCAGGGGGTGATTTCAGCCGCC
GTATCAACAAGGATTATGGCGACGACAACCTCAACCGTTTCGCAACAACGATCAATGCATTGCTCATCGGGGTAGACAAC
GGCGTCTCCGAGACCAGCCGCGTCATCGAAGGTCTGGCGCGTGGTGACCTGACAGAAAAGATGGACGGCGACTTCCGCGG
CGTCTTCGCCGAACTCAAGGAGAACGTCAACCAGACGCTGACCAAGCTGCGGGAAACGATGCGTGAAGTGCGCGGCAGCA
CGGAAGGCATCAGCGGCAACGCCAACGAGCTGCGCTCGGCCGCCGACGACCTGTCGAAGCGGACGGAACAGCAGGCCGCC
GCACTGGAGGAAACCTCCGCCGCGCTGGACGAAATCACCGCCGTTGTGCGTAATTCCACCGATCGTGCGCAGGAAGCCAG
CGCCATGGTTGCCGAAACCAAACAGAAGACGGAAGAATCCGCCAGTGTCGTGCGTGATGCCGTCTCCGCCATGGATCGCA
TCGAGCACGCCTCGCGCGAAATCAGCCAGATCATCAACGTAATCGATGAGATCGCCTTCCAGACCAACCTGCTGGCGCTG
AATGCCGGTGTGGAAGCGGCGCGTGCGGGCGAGGCTGGCAAGGGCTTTGCCGTCGTCGCCCAGGAAGTGCGCGAACTGGC
GCAGCGTTCCGCAACCGCGGCGAAGGACATCAAGGCGCTGATCACCAAATCCGGCGAGGAGGTTGGCCGCGGTGTGTCGC
TGGTGCAGAGAACGGGCAGCGCGTTGAGCGAGATCGAGACCCGCGTTCTCGCCATCAACGAGCATATCCATTCGATCGCC
ACGGCCGCCAGGGAGCAGTCCACCGGTCTGCACGAGGTGAATACTGCCATCAACCAGATGGACGAGGTGACGCAGCGCAA
CGCCGCCATGGTGGAGGAGACCTCGGCCGCGACCCATAAGCTGAGCAGCGAGGCGGACCATCTCGTAACACTGGTGACGC
GCTTCAATGTCGGCACCGAGACGGCGCAGCGCAGCCATCGTATCGAGCAATCTTTACGGCCGATGACGGCATCCACCGGG
CCGGTTGCCGTCTCCGGCAGGACGGCGGCCGTGTCGTCTCCGGCGCGTAAGCTGATGAACAGCGTCAGCCGTGCGCTCAA
TGCCCAGCCCGCCGCAGCCCCGGCGCATGGCGACTGGCAGGAATTCTAG

Upstream 100 bases:

>100_bases
AAATTCTTTCTTAACGCGGCATTGATAAATCTTGTGACGCGAAAAGTTATGCCAGCGTCCCATTTTCATCTTGGCGCTGG
TTTTTGTTGGGGGAACGAAA

Downstream 100 bases:

>100_bases
ACGACCTACCGTTTTGCCTCAAACCGGCTTAGCCTCAAGCGCCGCCCCTTTTCGGGCGGCGTTCGTTTTTCCGGCACTGA
AGACGTTTGTTTTGCAGCGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MRIRGRINLLVGLMSLVACTIGGLSIYAVSEFRVRTVEYEKAAERAYKGEALNRLVTAVVMEARGVYAAADIEKAAPFAD
GIVKNLDAMEKLIATWTPLVPAEQKATFDNLSSRFKEFKTFRLETARLAREAGPQAANQQGNNEANRANRKAYQAEIDAV
VKNDIAELEAVKAGIDGFVTTTFWLVITVTGSGILAGAAFGLYIGARQLSAPIRRVSEVMNAVADGNLDADVPYLGQNDE
IGEMAAAVEVFKKNGREVRRMNAQETAMRAKSDDLQAGMAVVVDAAAGGDFSRRINKDYGDDNLNRFATTINALLIGVDN
GVSETSRVIEGLARGDLTEKMDGDFRGVFAELKENVNQTLTKLRETMREVRGSTEGISGNANELRSAADDLSKRTEQQAA
ALEETSAALDEITAVVRNSTDRAQEASAMVAETKQKTEESASVVRDAVSAMDRIEHASREISQIINVIDEIAFQTNLLAL
NAGVEAARAGEAGKGFAVVAQEVRELAQRSATAAKDIKALITKSGEEVGRGVSLVQRTGSALSEIETRVLAINEHIHSIA
TAAREQSTGLHEVNTAINQMDEVTQRNAAMVEETSAATHKLSSEADHLVTLVTRFNVGTETAQRSHRIEQSLRPMTASTG
PVAVSGRTAAVSSPARKLMNSVSRALNAQPAAAPAHGDWQEF

Sequences:

>Translated_682_residues
MRIRGRINLLVGLMSLVACTIGGLSIYAVSEFRVRTVEYEKAAERAYKGEALNRLVTAVVMEARGVYAAADIEKAAPFAD
GIVKNLDAMEKLIATWTPLVPAEQKATFDNLSSRFKEFKTFRLETARLAREAGPQAANQQGNNEANRANRKAYQAEIDAV
VKNDIAELEAVKAGIDGFVTTTFWLVITVTGSGILAGAAFGLYIGARQLSAPIRRVSEVMNAVADGNLDADVPYLGQNDE
IGEMAAAVEVFKKNGREVRRMNAQETAMRAKSDDLQAGMAVVVDAAAGGDFSRRINKDYGDDNLNRFATTINALLIGVDN
GVSETSRVIEGLARGDLTEKMDGDFRGVFAELKENVNQTLTKLRETMREVRGSTEGISGNANELRSAADDLSKRTEQQAA
ALEETSAALDEITAVVRNSTDRAQEASAMVAETKQKTEESASVVRDAVSAMDRIEHASREISQIINVIDEIAFQTNLLAL
NAGVEAARAGEAGKGFAVVAQEVRELAQRSATAAKDIKALITKSGEEVGRGVSLVQRTGSALSEIETRVLAINEHIHSIA
TAAREQSTGLHEVNTAINQMDEVTQRNAAMVEETSAATHKLSSEADHLVTLVTRFNVGTETAQRSHRIEQSLRPMTASTG
PVAVSGRTAAVSSPARKLMNSVSRALNAQPAAAPAHGDWQEF
>Mature_682_residues
MRIRGRINLLVGLMSLVACTIGGLSIYAVSEFRVRTVEYEKAAERAYKGEALNRLVTAVVMEARGVYAAADIEKAAPFAD
GIVKNLDAMEKLIATWTPLVPAEQKATFDNLSSRFKEFKTFRLETARLAREAGPQAANQQGNNEANRANRKAYQAEIDAV
VKNDIAELEAVKAGIDGFVTTTFWLVITVTGSGILAGAAFGLYIGARQLSAPIRRVSEVMNAVADGNLDADVPYLGQNDE
IGEMAAAVEVFKKNGREVRRMNAQETAMRAKSDDLQAGMAVVVDAAAGGDFSRRINKDYGDDNLNRFATTINALLIGVDN
GVSETSRVIEGLARGDLTEKMDGDFRGVFAELKENVNQTLTKLRETMREVRGSTEGISGNANELRSAADDLSKRTEQQAA
ALEETSAALDEITAVVRNSTDRAQEASAMVAETKQKTEESASVVRDAVSAMDRIEHASREISQIINVIDEIAFQTNLLAL
NAGVEAARAGEAGKGFAVVAQEVRELAQRSATAAKDIKALITKSGEEVGRGVSLVQRTGSALSEIETRVLAINEHIHSIA
TAAREQSTGLHEVNTAINQMDEVTQRNAAMVEETSAATHKLSSEADHLVTLVTRFNVGTETAQRSHRIEQSLRPMTASTG
PVAVSGRTAAVSSPARKLMNSVSRALNAQPAAAPAHGDWQEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=295, Percent_Identity=40.6779661016949, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787690, Length=289, Percent_Identity=42.9065743944637, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788195, Length=263, Percent_Identity=43.7262357414449, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI2367378, Length=277, Percent_Identity=42.5992779783394, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1789453, Length=258, Percent_Identity=33.7209302325581, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73234; Mature: 73234

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRGRINLLVGLMSLVACTIGGLSIYAVSEFRVRTVEYEKAAERAYKGEALNRLVTAVV
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEARGVYAAADIEKAAPFADGIVKNLDAMEKLIATWTPLVPAEQKATFDNLSSRFKEFKT
HHHCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FRLETARLAREAGPQAANQQGNNEANRANRKAYQAEIDAVVKNDIAELEAVKAGIDGFVT
HHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTFWLVITVTGSGILAGAAFGLYIGARQLSAPIRRVSEVMNAVADGNLDADVPYLGQNDE
HHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
IGEMAAAVEVFKKNGREVRRMNAQETAMRAKSDDLQAGMAVVVDAAAGGDFSRRINKDYG
HHHHHHHHHHHHHCCHHHHHCCHHHHHHHHCCHHHHCCHHHEEECCCCCCHHHHHCCCCC
DDNLNRFATTINALLIGVDNGVSETSRVIEGLARGDLTEKMDGDFRGVFAELKENVNQTL
CCHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHH
TKLRETMREVRGSTEGISGNANELRSAADDLSKRTEQQAAALEETSAALDEITAVVRNST
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DRAQEASAMVAETKQKTEESASVVRDAVSAMDRIEHASREISQIINVIDEIAFQTNLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NAGVEAARAGEAGKGFAVVAQEVRELAQRSATAAKDIKALITKSGEEVGRGVSLVQRTGS
ECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALSEIETRVLAINEHIHSIATAAREQSTGLHEVNTAINQMDEVTQRNAAMVEETSAATHK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSEADHLVTLVTRFNVGTETAQRSHRIEQSLRPMTASTGPVAVSGRTAAVSSPARKLMN
HHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHH
SVSRALNAQPAAAPAHGDWQEF
HHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIRGRINLLVGLMSLVACTIGGLSIYAVSEFRVRTVEYEKAAERAYKGEALNRLVTAVV
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEARGVYAAADIEKAAPFADGIVKNLDAMEKLIATWTPLVPAEQKATFDNLSSRFKEFKT
HHHCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FRLETARLAREAGPQAANQQGNNEANRANRKAYQAEIDAVVKNDIAELEAVKAGIDGFVT
HHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTFWLVITVTGSGILAGAAFGLYIGARQLSAPIRRVSEVMNAVADGNLDADVPYLGQNDE
HHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
IGEMAAAVEVFKKNGREVRRMNAQETAMRAKSDDLQAGMAVVVDAAAGGDFSRRINKDYG
HHHHHHHHHHHHHCCHHHHHCCHHHHHHHHCCHHHHCCHHHEEECCCCCCHHHHHCCCCC
DDNLNRFATTINALLIGVDNGVSETSRVIEGLARGDLTEKMDGDFRGVFAELKENVNQTL
CCHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHH
TKLRETMREVRGSTEGISGNANELRSAADDLSKRTEQQAAALEETSAALDEITAVVRNST
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DRAQEASAMVAETKQKTEESASVVRDAVSAMDRIEHASREISQIINVIDEIAFQTNLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NAGVEAARAGEAGKGFAVVAQEVRELAQRSATAAKDIKALITKSGEEVGRGVSLVQRTGS
ECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALSEIETRVLAINEHIHSIATAAREQSTGLHEVNTAINQMDEVTQRNAAMVEETSAATHK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSEADHLVTLVTRFNVGTETAQRSHRIEQSLRPMTASTGPVAVSGRTAAVSSPARKLMN
HHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHH
SVSRALNAQPAAAPAHGDWQEF
HHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]