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The map label for this gene is deoC

Identifier: 159184174

GI number: 159184174

Start: 135859

End: 136632

Strand: Direct

Name: deoC

Synonym: Atu0132

Alternate gene names: 159184174

Gene position: 135859-136632 (Clockwise)

Preceding gene: 15887486

Following gene: 15887488

Centisome position: 4.78

GC content: 62.02

Gene sequence:

>774_bases
ATGGAACTCCAGCGTCCGCGCGAAGCGGCTGCCCTCACTTTGTCCTTGCTGGACCTGACCAATCTTAGGGAAGACTGCAC
GCCGCAGCAGATCGCAACCCTCTGCCAGCGGGCGCATACGGAGTTTGGCAACACCGCTGCCATTTGCATCTGGCCGCGTT
TCGTCGCGCAGGCCCGAGCGGCGTTCGGAAAAGACCACACGATTCGCATCGCAACGGTCGTGAATTTCCCCTCCGGCGAT
CTCGATGTCGCGACCGTGGTTGCGGAAACGGAAGCTGCAATCGGCGATGGCGCCGACGAAATCGATCTGGTCATTCCCTA
TCGTAAATTCATGGCAGGCGATGAATCGGCGGTGGCCGAAATGATCGCGGCCGTGCGTAAGGCTTGCGCGGCACCTGTGT
TGCTCAAGGTCATTCTTGAGACCGGTGAGCTGAAGGACAAGGCCCTGATCCGCCGTGCCTCGGAAATCGCCATTGCCGAA
GGGGCGGATTTCATCAAGACCTCGACCGGCAAGGTCGCCGTCAATGCCACGCTGGAAGCGGCCGATATCATGCTGCAGGC
GATCCGGGACAGCAAAAAGAAGGTGGGCTTCAAGCCGGCCGGCGGCATCGGCACGGTGGAGGACGCGACACTATACCTGC
GGCTGGCGGAAACCATCATGGCGCCCAACTGGGCCATGCCGTCGACCTTCCGTTTCGGTGCCTCGGGCGTCCTCGATGAT
GTGCTGAACGTGCTGGCCGGCGGCGAACCGGCCAAGGCCGCCAGCGGGTATTGA

Upstream 100 bases:

>100_bases
GCGCGGAACTGAGCCATGAAGAAACCAAGGATATGGCTCCCGTGGGCGGCAAAAGACTTGCCGCCATCCTAAAGGAAATG
ATCGCAGGAGGAGCGTGACC

Downstream 100 bases:

>100_bases
GCTTGATCCCGCAGGAAATCATCCGCCGCAAACGCGATGGCCTGTCGCTCGCGCCACAGGAGATTGCCGCTTTCATCGAA
GCGCTGTCGAAAGACGGCAT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MELQRPREAAALTLSLLDLTNLREDCTPQQIATLCQRAHTEFGNTAAICIWPRFVAQARAAFGKDHTIRIATVVNFPSGD
LDVATVVAETEAAIGDGADEIDLVIPYRKFMAGDESAVAEMIAAVRKACAAPVLLKVILETGELKDKALIRRASEIAIAE
GADFIKTSTGKVAVNATLEAADIMLQAIRDSKKKVGFKPAGGIGTVEDATLYLRLAETIMAPNWAMPSTFRFGASGVLDD
VLNVLAGGEPAKAASGY

Sequences:

>Translated_257_residues
MELQRPREAAALTLSLLDLTNLREDCTPQQIATLCQRAHTEFGNTAAICIWPRFVAQARAAFGKDHTIRIATVVNFPSGD
LDVATVVAETEAAIGDGADEIDLVIPYRKFMAGDESAVAEMIAAVRKACAAPVLLKVILETGELKDKALIRRASEIAIAE
GADFIKTSTGKVAVNATLEAADIMLQAIRDSKKKVGFKPAGGIGTVEDATLYLRLAETIMAPNWAMPSTFRFGASGVLDD
VLNVLAGGEPAKAASGY
>Mature_257_residues
MELQRPREAAALTLSLLDLTNLREDCTPQQIATLCQRAHTEFGNTAAICIWPRFVAQARAAFGKDHTIRIATVVNFPSGD
LDVATVVAETEAAIGDGADEIDLVIPYRKFMAGDESAVAEMIAAVRKACAAPVLLKVILETGELKDKALIRRASEIAIAE
GADFIKTSTGKVAVNATLEAADIMLQAIRDSKKKVGFKPAGGIGTVEDATLYLRLAETIMAPNWAMPSTFRFGASGVLDD
VLNVLAGGEPAKAASGY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=248, Percent_Identity=39.1129032258064, Blast_Score=147, Evalue=8e-36,
Organism=Escherichia coli, GI1790841, Length=249, Percent_Identity=55.421686746988, Blast_Score=233, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17533015, Length=252, Percent_Identity=38.8888888888889, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI19922098, Length=259, Percent_Identity=38.2239382239382, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_AGRT5 (Q8UJ09)

Other databases:

- EMBL:   AE007869
- PIR:   AF2592
- PIR:   H97374
- RefSeq:   NP_353168.2
- ProteinModelPortal:   Q8UJ09
- SMR:   Q8UJ09
- STRING:   Q8UJ09
- GeneID:   1132170
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0132
- eggNOG:   COG0274
- HOGENOM:   HBG636421
- OMA:   CKEACGD
- PhylomeDB:   Q8UJ09
- ProtClustDB:   PRK05283
- BioCyc:   ATUM176299-1:ATU0132-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00592
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 27246; Mature: 27246

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: ACT_SITE 168-168 ACT_SITE 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELQRPREAAALTLSLLDLTNLREDCTPQQIATLCQRAHTEFGNTAAICIWPRFVAQARA
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHH
AFGKDHTIRIATVVNFPSGDLDVATVVAETEAAIGDGADEIDLVIPYRKFMAGDESAVAE
HCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHCCCHHHHHH
MIAAVRKACAAPVLLKVILETGELKDKALIRRASEIAIAEGADFIKTSTGKVAVNATLEA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEHHHH
ADIMLQAIRDSKKKVGFKPAGGIGTVEDATLYLRLAETIMAPNWAMPSTFRFGASGVLDD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
VLNVLAGGEPAKAASGY
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MELQRPREAAALTLSLLDLTNLREDCTPQQIATLCQRAHTEFGNTAAICIWPRFVAQARA
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHH
AFGKDHTIRIATVVNFPSGDLDVATVVAETEAAIGDGADEIDLVIPYRKFMAGDESAVAE
HCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHCCCHHHHHH
MIAAVRKACAAPVLLKVILETGELKDKALIRRASEIAIAEGADFIKTSTGKVAVNATLEA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEHHHH
ADIMLQAIRDSKKKVGFKPAGGIGTVEDATLYLRLAETIMAPNWAMPSTFRFGASGVLDD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
VLNVLAGGEPAKAASGY
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194