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The map label for this gene is deoD [H]

Identifier: 15887486

GI number: 15887486

Start: 135056

End: 135856

Strand: Direct

Name: deoD [H]

Synonym: Atu0131

Alternate gene names: 15887486

Gene position: 135056-135856 (Clockwise)

Preceding gene: 159184173

Following gene: 159184174

Centisome position: 4.75

GC content: 60.3

Gene sequence:

>801_bases
ATGACGGACGGTCTGATCGATATTCTGGTGGAGCGCCTGAACGGCCTCATGCCGCGCGTCGCCATAGTTCTGGGGTCTGG
CCTTGGTTCGCTGGTGGAAGAGGTAAGCGATCCGATCCGCGTGCCCTATGCCAATCTTCCCGGCTTCCCCACAAGCGGCG
TTTCCGGCCATGCGGGCGAGCTGGTGGCTGGTTATCTGGGTGGTGAGCCTGTCATGATGCTCTCCGGCCGGGTGCATTAT
TACGAAAAGGGTGATCCGGCCGCCATGCGCGCGGTCATCGAAGCGCTTGCCGGTCTCGGCGTACAATCGCTCATCCTCAC
CAATTCGGCGGGTTCAGTCAGGCAGGACATGCCGCCCGGCTCGGTCATGCAGATCACTGACCATATCAATTATTCCGGCA
TGAACCCGCTGATCGGTGAAGAAAGCGACCGCCGCTTCGTTGGCATGACTACGGCTTATGATCCGGATCTCATGCTCGCC
ATGCGCAATGCCGCCATCCGCGCGACAGTTCCGCTGTTCGGCGGCGTCTATATGTGGTTTTCGGGACCGAGCTTCGAAAC
GCCGGCAGAAATCCGCATGGCGCGGGTGCTGGGTGCAGATGCCGTCGGCATGTCCACGGTGCCGGAAGTCATCCTTGCGC
GCTTTTTCGGGATGCGCGTTGCTGCCGCATCGGTTATTACCAACTACGGTGCCGGCATGACCGGCGCGGAACTGAGCCAT
GAAGAAACCAAGGATATGGCTCCCGTGGGCGGCAAAAGACTTGCCGCCATCCTAAAGGAAATGATCGCAGGAGGAGCGTG
A

Upstream 100 bases:

>100_bases
CGCCGGAGACGAAGATTTATCTTTGCGACGAAACTGGCGTCCAGAAAGTCATGACCATGGAAGAGCTTTTGCCCTCCGTC
TTCAAGACCGAGCTGCCCTG

Downstream 100 bases:

>100_bases
CCATGGAACTCCAGCGTCCGCGCGAAGCGGCTGCCCTCACTTTGTCCTTGCTGGACCTGACCAATCTTAGGGAAGACTGC
ACGCCGCAGCAGATCGCAAC

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: Inosine phosphorylase; Purine nucleoside phosphorylase I; PNP I; PU-NPase I [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTDGLIDILVERLNGLMPRVAIVLGSGLGSLVEEVSDPIRVPYANLPGFPTSGVSGHAGELVAGYLGGEPVMMLSGRVHY
YEKGDPAAMRAVIEALAGLGVQSLILTNSAGSVRQDMPPGSVMQITDHINYSGMNPLIGEESDRRFVGMTTAYDPDLMLA
MRNAAIRATVPLFGGVYMWFSGPSFETPAEIRMARVLGADAVGMSTVPEVILARFFGMRVAAASVITNYGAGMTGAELSH
EETKDMAPVGGKRLAAILKEMIAGGA

Sequences:

>Translated_266_residues
MTDGLIDILVERLNGLMPRVAIVLGSGLGSLVEEVSDPIRVPYANLPGFPTSGVSGHAGELVAGYLGGEPVMMLSGRVHY
YEKGDPAAMRAVIEALAGLGVQSLILTNSAGSVRQDMPPGSVMQITDHINYSGMNPLIGEESDRRFVGMTTAYDPDLMLA
MRNAAIRATVPLFGGVYMWFSGPSFETPAEIRMARVLGADAVGMSTVPEVILARFFGMRVAAASVITNYGAGMTGAELSH
EETKDMAPVGGKRLAAILKEMIAGGA
>Mature_265_residues
TDGLIDILVERLNGLMPRVAIVLGSGLGSLVEEVSDPIRVPYANLPGFPTSGVSGHAGELVAGYLGGEPVMMLSGRVHYY
EKGDPAAMRAVIEALAGLGVQSLILTNSAGSVRQDMPPGSVMQITDHINYSGMNPLIGEESDRRFVGMTTAYDPDLMLAM
RNAAIRATVPLFGGVYMWFSGPSFETPAEIRMARVLGADAVGMSTVPEVILARFFGMRVAAASVITNYGAGMTGAELSHE
ETKDMAPVGGKRLAAILKEMIAGGA

Specific function: Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI157168362, Length=223, Percent_Identity=43.9461883408072, Blast_Score=163, Evalue=1e-40,
Organism=Escherichia coli, GI1788746, Length=242, Percent_Identity=42.9752066115703, Blast_Score=200, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17541190, Length=250, Percent_Identity=38, Blast_Score=168, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323238, Length=224, Percent_Identity=42.8571428571429, Blast_Score=164, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24656093, Length=270, Percent_Identity=36.2962962962963, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI45552887, Length=270, Percent_Identity=36.2962962962963, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24656090, Length=270, Percent_Identity=36.2962962962963, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI45552885, Length=270, Percent_Identity=36.2962962962963, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24762376, Length=242, Percent_Identity=32.2314049586777, Blast_Score=107, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011268
- InterPro:   IPR000845
- InterPro:   IPR011270
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 27933; Mature: 27802

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGLIDILVERLNGLMPRVAIVLGSGLGSLVEEVSDPIRVPYANLPGFPTSGVSGHAGE
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
LVAGYLGGEPVMMLSGRVHYYEKGDPAAMRAVIEALAGLGVQSLILTNSAGSVRQDMPPG
HHHHHCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHCCCHHHHEEECCCCCHHHCCCCC
SVMQITDHINYSGMNPLIGEESDRRFVGMTTAYDPDLMLAMRNAAIRATVPLFGGVYMWF
CEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCHHEEECHHHCCEEEEE
SGPSFETPAEIRMARVLGADAVGMSTVPEVILARFFGMRVAAASVITNYGAGMTGAELSH
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EETKDMAPVGGKRLAAILKEMIAGGA
HHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDGLIDILVERLNGLMPRVAIVLGSGLGSLVEEVSDPIRVPYANLPGFPTSGVSGHAGE
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
LVAGYLGGEPVMMLSGRVHYYEKGDPAAMRAVIEALAGLGVQSLILTNSAGSVRQDMPPG
HHHHHCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHCCCHHHHEEECCCCCHHHCCCCC
SVMQITDHINYSGMNPLIGEESDRRFVGMTTAYDPDLMLAMRNAAIRATVPLFGGVYMWF
CEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCHHEEECHHHCCEEEEE
SGPSFETPAEIRMARVLGADAVGMSTVPEVILARFFGMRVAAASVITNYGAGMTGAELSH
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EETKDMAPVGGKRLAAILKEMIAGGA
HHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10537218; 8969508; 9384377; 1629150 [H]