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The map label for this gene is appC [H]

Identifier: 15889846

GI number: 15889846

Start: 2566051

End: 2567226

Strand: Direct

Name: appC [H]

Synonym: Atu2589

Alternate gene names: 15889846

Gene position: 2566051-2567226 (Clockwise)

Preceding gene: 159185280

Following gene: 159185281

Centisome position: 90.3

GC content: 58.84

Gene sequence:

>1176_bases
ATGACTTCATCCATTCCGAAATCAGGCGAAGCGCTGCCCCATTACGTCTCGACGGCACCCTTCGACCCGTCGCTCATCGA
ACCCAACACCTCTGGAATGGCGGCCTTCAGCAAGGCATCACAGCTGAAGCTGATGTGGTGGCAATTCCGCCAGCACAAGA
TCGCTGTGTGGTCCGGCGCGTTTCTGGCGCTGATCTATCTTTCGATCCTGATCAGCGAGTTCCTCGCCCCTTACAATCTT
CATACCCGCAATATCGAGCATATCTACGCGCCGCCGCAGGCTATCCACCTCTTCGACGACGGAAAATTTGTCGGTCCCTT
CGTTTATGGCCGGGAAATGACGCTCGACATGGACAATCTGAGGCGCGTCTACCGGGATGTGCCGACGGATATCCAGCCGC
TGCGCTTCTTTTGCAAGGGCGATACCTATCGCTTCTGGGGCATGTTTGAGGGCAGAACCCACTTTGTATGCCCGGCCGAA
GGCGGTGAAATGTTCCTGCTCGGCACTGACAGGCTGGGGCGCGATGTGCTGTCGCGGATTATCTACGGCGCGCGCATCTC
GCTGACCATCGGTCTTCTCGGTGTTGCCATGAGCTTCGTTCTCGGCATTGTGATCGGCGGTCTGGCGGGCTATCGCGGCG
GCACCTTTGACCTGATTGTCCAGCGCATCATCGAGGTGCTGCAATCCATCCCCAGCATTCCTCTCTGGCTGGCGCTGGCG
GCCATCATGCCGGTGACCTGGAGTCCGATCCTCGTCTATCTCGGCATCACCATCATTCTCGGCATGCTGGACTGGACGGG
CCTTGCGCGCGCCGTGCGCTCGAAGCTTCTGGCGCTTCGCGAGGAAGACTATGTTTTATCTGCGCAATTGATGGGTGCCG
GCACACCGCGCATCATCGGCAGACACCTTATCCCCGGCTTCATGTCGCATCTCATCGCTTCGGCCACCCTGACGATACCC
GGCATGATTCTCGGCGAGACCGCCCTGAGCTTCCTCGGCCTGGGTCTCAGGCCACCGATCACAAGTTGGGGAATTCTGCT
CACGGAGGCGCGCAGCGTCAGCGTCATTGCGCTATATCCGTGGCTTCTCATCCCGACGATCCCGGTCGTTCTCGTCATTC
TGGCCTTTAATTTCTTCGGCGACGGACTACGTGATGCTGCGGACCCCTTCAGATAA

Upstream 100 bases:

>100_bases
TGATGTTCCTGGCTTTCCTGACGGTGATCGGCGTTCTGGTGTCGGATATCGCCCTTGCCATACTCGACCCGCGCATCCGC
TTCGGAGGTGGTAACGTCAA

Downstream 100 bases:

>100_bases
AATGGAATACACCTTGATCTATTGCCCTTCAGCCATCGCCTTTTTTGTGGAAGGCAAAAAGAGGTGTGGCCCATGAGCCC
TCGTTTGAACGACGCGCGCA

Product: ABC transporter, membrane spanning protein (oligopeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTSSIPKSGEALPHYVSTAPFDPSLIEPNTSGMAAFSKASQLKLMWWQFRQHKIAVWSGAFLALIYLSILISEFLAPYNL
HTRNIEHIYAPPQAIHLFDDGKFVGPFVYGREMTLDMDNLRRVYRDVPTDIQPLRFFCKGDTYRFWGMFEGRTHFVCPAE
GGEMFLLGTDRLGRDVLSRIIYGARISLTIGLLGVAMSFVLGIVIGGLAGYRGGTFDLIVQRIIEVLQSIPSIPLWLALA
AIMPVTWSPILVYLGITIILGMLDWTGLARAVRSKLLALREEDYVLSAQLMGAGTPRIIGRHLIPGFMSHLIASATLTIP
GMILGETALSFLGLGLRPPITSWGILLTEARSVSVIALYPWLLIPTIPVVLVILAFNFFGDGLRDAADPFR

Sequences:

>Translated_391_residues
MTSSIPKSGEALPHYVSTAPFDPSLIEPNTSGMAAFSKASQLKLMWWQFRQHKIAVWSGAFLALIYLSILISEFLAPYNL
HTRNIEHIYAPPQAIHLFDDGKFVGPFVYGREMTLDMDNLRRVYRDVPTDIQPLRFFCKGDTYRFWGMFEGRTHFVCPAE
GGEMFLLGTDRLGRDVLSRIIYGARISLTIGLLGVAMSFVLGIVIGGLAGYRGGTFDLIVQRIIEVLQSIPSIPLWLALA
AIMPVTWSPILVYLGITIILGMLDWTGLARAVRSKLLALREEDYVLSAQLMGAGTPRIIGRHLIPGFMSHLIASATLTIP
GMILGETALSFLGLGLRPPITSWGILLTEARSVSVIALYPWLLIPTIPVVLVILAFNFFGDGLRDAADPFR
>Mature_390_residues
TSSIPKSGEALPHYVSTAPFDPSLIEPNTSGMAAFSKASQLKLMWWQFRQHKIAVWSGAFLALIYLSILISEFLAPYNLH
TRNIEHIYAPPQAIHLFDDGKFVGPFVYGREMTLDMDNLRRVYRDVPTDIQPLRFFCKGDTYRFWGMFEGRTHFVCPAEG
GEMFLLGTDRLGRDVLSRIIYGARISLTIGLLGVAMSFVLGIVIGGLAGYRGGTFDLIVQRIIEVLQSIPSIPLWLALAA
IMPVTWSPILVYLGITIILGMLDWTGLARAVRSKLLALREEDYVLSAQLMGAGTPRIIGRHLIPGFMSHLIASATLTIPG
MILGETALSFLGLGLRPPITSWGILLTEARSVSVIALYPWLLIPTIPVVLVILAFNFFGDGLRDAADPFR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=223, Percent_Identity=38.1165919282511, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787498, Length=231, Percent_Identity=39.3939393939394, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789964, Length=233, Percent_Identity=39.0557939914163, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1788505, Length=363, Percent_Identity=31.9559228650138, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789889, Length=228, Percent_Identity=32.8947368421053, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787760, Length=223, Percent_Identity=34.0807174887892, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787549, Length=227, Percent_Identity=32.5991189427313, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43238; Mature: 43106

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSIPKSGEALPHYVSTAPFDPSLIEPNTSGMAAFSKASQLKLMWWQFRQHKIAVWSGA
CCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEHHH
FLALIYLSILISEFLAPYNLHTRNIEHIYAPPQAIHLFDDGKFVGPFVYGREMTLDMDNL
HHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEECCCCEECCEEECCEEEECHHHH
RRVYRDVPTDIQPLRFFCKGDTYRFWGMFEGRTHFVCPAEGGEMFLLGTDRLGRDVLSRI
HHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCEEEEECCHHHHHHHHHH
IYGARISLTIGLLGVAMSFVLGIVIGGLAGYRGGTFDLIVQRIIEVLQSIPSIPLWLALA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
AIMPVTWSPILVYLGITIILGMLDWTGLARAVRSKLLALREEDYVLSAQLMGAGTPRIIG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHH
RHLIPGFMSHLIASATLTIPGMILGETALSFLGLGLRPPITSWGILLTEARSVSVIALYP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEHHHH
WLLIPTIPVVLVILAFNFFGDGLRDAADPFR
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure 
TSSIPKSGEALPHYVSTAPFDPSLIEPNTSGMAAFSKASQLKLMWWQFRQHKIAVWSGA
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEHHH
FLALIYLSILISEFLAPYNLHTRNIEHIYAPPQAIHLFDDGKFVGPFVYGREMTLDMDNL
HHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEECCCCEECCEEECCEEEECHHHH
RRVYRDVPTDIQPLRFFCKGDTYRFWGMFEGRTHFVCPAEGGEMFLLGTDRLGRDVLSRI
HHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCEEEEECCHHHHHHHHHH
IYGARISLTIGLLGVAMSFVLGIVIGGLAGYRGGTFDLIVQRIIEVLQSIPSIPLWLALA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
AIMPVTWSPILVYLGITIILGMLDWTGLARAVRSKLLALREEDYVLSAQLMGAGTPRIIG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHH
RHLIPGFMSHLIASATLTIPGMILGETALSFLGLGLRPPITSWGILLTEARSVSVIALYP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEHHHH
WLLIPTIPVVLVILAFNFFGDGLRDAADPFR
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]